Ib tug uas nws kim heev pab pawg neeg ntawm cov tshuaj - tshuaj tua kab mob tetracycline

Tetracycline tshuaj tua kab mob - nws yog ib tug loj pawg ntawm cov tshuaj. Medicaments muaj ib tug zoo tshuaj qauv. Nws yuav tsum tau muab sau tseg tias cov nyiaj yog ib tug ntawm cov uas lub qhov chaw ntawm ib sab spectrum ntawm kev ua si ntawm cov tshuaj.

Tetracycline tshuaj tua kab mob. piav qhia

Tshuaj nyob rau hauv pab pawg neeg no muaj ib tug depressing ntxim rau cov tu tub tu kiv thiab kev loj hlob ntawm gram-tsis zoo, gram-zoo cov kab mob, nrog (ntawm acid), loj cov kab mob, lwm cov kab mob. Cov qeb muaj xws li tshuaj xws li "chlortetracycline hydrochloride", "Oxytetracycline hydrochloride", "tetracycline" thiab lwm tus neeg. Tshuaj kev tshawb no yog pib nyob rau hauv 1948. Vim ib co teeb meem nyob rau hauv tau txais hluavtaws tshuaj ntawm hnub no yog tsim siv biosynthesis. Tag nrho tetracycline tshuaj tua kab mob txawv amphoteric cim. Lawv yooj yim zoo vim dimethylamino pab pawg neeg. Nws cov tshuaj muaj acidic zog vim yog lub phenolic hydroxyl ntawm D-ntiv nplhaib. Raws li ib tug amphoteric compound soluble nyob rau hauv acid thiab alkali, txoj kev ua rau ntsev. Lawv, nyob rau hauv lem hydrolyzed nyob rau hauv aqueous daws teeb meem. Kom ntau tiv thaiv acid hydrolysis txheej txheem, thiab los nag puag precipitate.

Tag nrho tetracycline tebchaw muaj spectra uas zoo xws li txhua lwm yam. Nyob rau hauv lub lwg me me ntawm lub phenolic hydroxyl ua rau lub hloov xim los ntawm cov tshuaj tiv thaiv nrog ferric chloride (3). Tetracycline tshuaj tua kab mob decompose tsim alkali izotetratsiklinov. Nyob rau hauv lem, qhov no yog nrog los ntawm ib tug nce nyob rau hauv lub painting. general cov tshuaj tiv thaiv cov yam ntxwv ntawm tag nrho cov tetracycline tebchaw. Npaj paub qhov txawv ntawm txhua lwm yam yog tau ua tsaug rau txawv uas tseg tau nyob rau hauv tus ntawm sulfuric acid (feeb meej). Qhov no yog nrog los ntawm cov tsim ntawm lub tebchaw, dawb lias rau txhua tetracycline nyob rau hauv nws cov xim. Yog li ntawd, piv txwv li, rau ib tug muaj ib cov ntshav-liab Hawj txawm, rau lwm - ntshav. Ib tug ntawm cov yam ntxwv yog xav tau cov tshuaj muaj peev xwm mus fluoresce nyob rau hauv tus ntawm UV teeb. Nws yog feem ntau siv raws li pov thawj ntawm lawv authenticity.

Pharmacological tetracycline

Tej kev npaj no txawv sufficiently sab spectrum ntawm kev ua si. Nws bacteriostatic nyhuv yog vim inhibition ntawm cov protein synthesis causative tus kab mob. tshuaj ua si no yog muaj txheeb ze rau aerobic gram-zoo cov kab mob, xws li kab mob los ua penicillinase. Cov tshuaj kuj muaj feem xyuam rau lub gram-tsis zoo kab mob. Sau tshuaj kuj me me kab mob, feem ntau fungi thiab ib tug xov tooj ntawm lwm yam kab mob los.

Ib txhia tshuaj tua kab mob nkag cai. phiv tshua

Nws yog pom zoo kom siv cov tshuaj nyob rau hauv ib koob tshuaj ntawm 0.3 grams ntawm thawj ob lub hnub, 0.2 grams ntawm tsib lub sij hawm nyob rau hauv lub nram qab no hnub. Gonorrhea (subacute thiab mob uncomplicated) rau hauv chav kawm tshuaj rau 5 g, nrog rau lwm cov ntaub ntawv - 10. Nws yog pom zoo kom noj cov tshuaj ua ntej los yog thaum lub sij hawm ib tug noj mov. Tawm tsam tom qab ntawm yuav mob plab, ntuav, xeev siab.