Glycosylated hemoglobin thiab physiological tseem ceeb

Lub ntsiab qauv tshau rau cov kev kho mob ntawm cov ntshav qab zib yog mus cuag ib tug ruaj khov physiological concentration ntawm qab zib (glucose) nyob rau hauv cov ntshav. Tswj cov ntshav qab zib muaj peev xwm yuav ua nyob rau hauv tsev siv ib portable zib meters, raws li zoo raws li nyob rau hauv cov kev kuaj. Raws li kev soj ntsuam ntawm ib tug tib txoj kev tshawb no ntawm lub concentration ntawm qab zib nyob rau hauv cov ntshav yog tsis tau mus txiav txim rau lub xeev ntawm carbohydrate metabolism hauv lub cev. Tam sim no, tsim ib txoj kev txiav txim rau qhov nyiaj ntawm glycosylated hemoglobin nyob rau hauv uas lub sij hawm los mus ntsuam xyuas tus txheej xwm ntawm carbohydrate metabolism. Heev heev cov kev tshawb fawb ua DCCT (Mob ntshav qab zib Control Committee thiab nws cov kev soj ntsuam mob), nws twb pom hais tias cov piam thaj theem yog zoo correlated nrog tus neeg mob cov ntshav qabzib. Glycated hemoglobin - zoo qhia ntawm cov hauj lwm zoo ntawm tshuaj kho mob rau cov kab mob ntawm cov ntshav qab zib.

Glycated hemoglobin yog tsim nyob rau hauv tas li ntawd mus rau lub nitrogen hexose davhlau ya nyob twg cov cheeb tsam ntawm beta-globin chains ntawm hemoglobin A1 chav kawm ntawv (HbA1c). Tsim HbA1c tso nyob rau hauv cov ntshav liab (erythrocytes) thiab muab khaws cia tseg muaj ib puas thiab kaum-ib puas thiab peb caug hnub (lub sij hawm ntawm lub neej ntawm lub cell). Raws li qhov ntsuas no, koj yuav txiav txim seb lub theem ntawm qab zib nyob rau hauv tus neeg mob rau 2-3 lub hlis ua ntej rau txoj kev tshawb.

Glycosylated hemoglobin, thiab nws cov concentration yog ncaj qha proportional rau tus nqi ntawm zib nyob rau hauv cov ntshav. Yuav ua li cas Kuv yuav txiav txim cov theem nyob rau hauv cov ntshav? Yuav kom txiav txim no parameter yog qhov zoo tshaj plaws los mus siv tshwj xeeb xeem systems. Nws yog tseem tau mus siv lwm yam instrumental diagnostic txoj kev: gas-kua chromatography thiab affinity electrophoresis, immunoelectrophoresis, etc. Glycosylated hemoglobin tus nqi rau cov neeg noj qab yog nruab nrab ntawm 4 thiab 6%. Ntshav qab zib cov neeg mob uas hyperglycemia glycosylated hemoglobin nce ob mus rau peb lub sij hawm.

Hemoglobin nyob rau hauv cov me nyuam yog ntawm kev tseem ceeb vim hais tias nyob rau hauv lub loj hlob kab mob metabolism yog ho muaj dua piv rau cov neeg laus. Yog li ntawd, cov niam txiv yuav tsum tau paub txog thiab soj ntsuam cov theem ntawm hemoglobin nyob rau hauv cov ntshav ntawm tus me nyuam. Qhov no yog tsim nyog los tiv thaiv kom txhob hlau tsis muaj peev xwm anemia. Hauv plawv ntawm txoj kev loj hlob ntawm tus kab mob no yog Ferum tsis muaj peev xwm nyob rau hauv lub cev, uas yog kev koom tes nyob rau hauv lub synthesis ntawm hemoglobin. Pa deprivation adversely muaj feem xyuam rau txoj kev loj hlob ntawm lub paj hlwb, lub cev tsis thiab kab systems. Qhov tseem raug rau hlau tsis muaj peev xwm anemia nyob rau hauv cov me nyuam muaj hnub nyoog 9 hlis mus rau 5 xyoo.

Tam sim no, mob ntshav qab zib tswj yog nqa tawm nrog kev pab los ntawm daim ntawv lub Accu-Chek 360 °. Nrog daim ntawv no ntawm tus kws kho mob npe tus neeg mob lub zib theem nyob rau hauv kev yoo mov thiab postprandial. Qhov zoo tshaj txoj kev uas yuav txo cov ntshav qab zib concentration yog siv cov ntev-kuj insulin. Siv cov Accu-Chek 360 ° txhawb kom xaiv regimen insulin. Yog li peb txo cov theem ntawm cov ntshav qab zib mus rau lub qub physiological ntau yam. Muaj ntau cov kws txawj hais lus cam uas siv daim ntawv no ntawm cov ntshav qab zib tswj yuav ua tau zoo rau ib tug ob peb lub hlis mus rau txo lub theem ntawm glycated hemoglobin mus rau tsib-rau units (physiological cai).

Yog li ntawd, yog hais tias koj tau raug tshuaj lawm "cov ntshav qab zib", tsis txhob tag kev cia siab, muab thiab tau daig rau lub tswv yim hais tias lub neej no twb tshaj. Rau lawv noj qab haus huv yuav tsum tau nyob. Cov neeg uas muaj ntshav qab zib yuav pheej saib xyuas lub concentration ntawm qab zib nyob rau hauv cov ntshav. Nws yog yooj yim npaum li mus nqa tawm cov kev tshawb fawb nyob rau hauv lub tsev tshaj nyob rau hauv lub queues lub tsev kho mob. Nrog rau kev siv uas niaj hnub ntaub ntawv ntawm qhov Accu-Chek 360 ° glyukomerov koj yuav tau yooj yim tswj koj cov ntshav qab zib theem.