Poov xab-zoo li fungi ntawm lub genus Candida

Yog li ntawd lub ntiaj teb no uas peb txhua tus yog surrounded los ntawm txhiab ntawm me me creatures. peb yog cov liab qab qhov muag yuav tsis pom lawv, tab sis tuaj rau hauv kev sib cuag nrog lawv txhua txhua feeb. Ib txhia "pom" pab tau peb, lwm leej lwm tus raug tua, thiab lwm tus neeg yuav coj, thiab cov kev tsim txom thiab kev pab. Poov xab-zoo li fungi ntawm lub genus Candida yog xws li microbes uas tsis tiv thaiv kom txhob rau peb kom peb nyob kaj siab lug puas tau tom qab, tab sis nyob rau hauv tej lub sijhawm pib coj aggressively, ua kab mob Candidiasis los yog qhov ncauj tawm. Vim hais tias cov kab tsis yog ib txwm txawm, lawv hu ua opportunistic. Tag nrho cov sab 186 hom fungi ntawm lub genus Candida, tab sis qhov kev nyab xeeb ntawm tsuas yog ob tug teb hom. Nyob rau lawv yuav tsum tau tham nyob rau hauv no tsab xov xwm.

Lub genus Candida fungi: yam ntxwv

Candida poov xab teej tug mus rau lub genus. Feem ntau ntawm hom yog kiag li txawm thiab nyob rau hauv lub cev ntawm cov tshuaj yej pwm nyob rau hauv yogurt, lwm yam khoom noj siv mis, raws li zoo raws li nyob rau hauv lub mob huam ntawm tus txiv neej, uas qhia ib tug ib feem ntawm ib tug noj qab nyob zoo plab hnyuv muaj. Yog ho nphav kiag ntawm lub genus Candida yog aerobic, piv txwv li, muaj ib tug active lub neej nyob rau hauv lub xub ntiag ntawm oxygen. Lawv yuav muaj nyob rau hauv ob hom - poov xab thiab micellar. Nyob rau hauv poov fungi yog yeej los yog dawb budding blastospores thiab multiply. Lub micellar daim ntawv ntawm fungal hlwb elongate, xa mus rau hauv pseudomycelia. Tsis zoo li yeej muaj tseeb, yog tsis muaj partitions, tab sis muaj ib tug constriction. Lawv nyob blastospores, thiab davhlau ya nyob twg expansions hlamidiospory double-clad. Lub micellar daim ntawv ntawm fungi yuav tau mus ua niam txiv.

Lwm yam creatures dimorphic fungi ntawm lub genus Candida yog txawv nyob rau hauv hais tias lawv yuav ua tau nyob rau hauv lub cev ntawm nws tus tswv nyob rau hauv ob ntawm nws cov ntaub ntawv, tab sis tsis tau hloov lawv nyob rau hauv lub ambient kub.

Ib qho tseem ceeb cov khoom teejtug uas Candida - lawv yog cov muaj peev xwm mus ferment maltose thiab piam thaj.

Candidiasis kab mob, raws li tsis ntev los no kev tshawb fawb, qhov ua rau ntawm txog 20 hom ntawm fungi, thiab yog cov feem ntau txaus ntshai C.Albicans (60%) thiab C.Tropicalis (20%). Qhov seem 18 hom lug faib thiab tsawg yam teeb meem loj rau cov xwm txheej ntawm Candidiasis tsis muaj.

Qhia qhov tseemceeb txog pathogenic hom

Cov feem ntau ces yuav tsum fungi ntawm lub genus Candida, hu ua C.Albicans. Lawv muaj cov kwv yees li 8 tawm ntawm 10. Feem ntau ntawm cov fungi nkag mus rau hauv lub cev rau tus me nyuam thaum yug los thiab ua neej nyob tsis muaj disturbing, nyob rau hauv lub qhov ncauj kab noj hniav, txoj hlab nqos mov thiab cov hnyuv. Nyob rau hauv cov poj niam, lawv kuj yog ib feem ntawm lub paum microflora. Nws yog ib qhov zoo ntawm Candida feem ntau lub luag hauj lwm rau qhov tshwm sim ntawm Candidiasis.

Qhov thib ob hom yog hu ua ib tug txaus ntshai C.Tropicalis. Cov fungi yuav tau txeem mus rau hauv cov ntshav thiab siv nws los populate lub peripheral kabmob. Tsis ntev los no kev tshawb fawb tau qhia ib tug feature ntawm Candida C.Tropicalis ua hauj lwm nyob rau hauv tandem nrog Serratia marcescens thiab Escherichia coli, thiab qhov ua rau ntawm Crohn tus kab mob.

Tsis heev, tab sis pom tau hais tias yuav tsum tau lub feem ntau txaus ntshai fungi ntawm lub genus Candida poov xab hom C.Krusei. Lawv yog cov resistant mus rau yeeb tshuaj "Fluconazole", siv nyob rau hauv cov kev kho mob ntawm fungal kab mob, li ntawd, nws yog ib qho tseem ceeb qha lub hom pathogenic pwm afflicting tus neeg mob.

Yog ho nphav kiag Candida hom C.Glabrata xam tau tias yog non-pathogenic. Lawv muaj nyob rau hauv nws lub poov xab daim ntawv thiab cov me nyuam tsuas budding. Nyob rau hauv feem ntau tus neeg mob, Candida Glabrata kuaj txog urinary catheters, qhov twg nws cov ntaub ntawv ib tug nyias biofilm. Qhov no pwm ua urogenital Candidiasis.

Candida hom C.Parapsilosis feem ntau ua ib tug ua ntawm sepsis. Nws muaj peev xwm sawv ntawm kis tus mob, tshwj xeeb tshaj yog yog hais txawv teb chaws cov khoom tau mus rau hauv lawv.

Hom ntawm fungi thiab C.Rugosa C.Lusitaniae thiab lwm tus neeg ntawm cov genus Candida yog tsis tshua muaj heev. Piv txwv li, C.Lusitaniae nyob rau hauv lub sij hawm ntawm 1979 rau 1990 twb ntes tau xwb nyob rau hauv 30 cov neeg mob.

Txoj kev uas kab mob

Conditionally - pathogenic fungi poov ntawm lub genus Candida nyob rau hauv lub chav kawm ntawm evolution tau tsim mechanisms uas pab kom lawv ua tau ib tug cab hav zoov. Lawv yog cov tau mas ntev-lub sij hawm khov thiab kom qhuav. Sau cov tib neeg lub cev, lawv yuav ua tau ib tug qias neeg thiab tsis zoo ua zaub mov uas muaj qias neeg ob txhais tes thiab lwm yam khoom, xws li nceb C.Parapsilosis kis txhab nrog lub infiltration ntawm txawv teb chaws tej khoom, xws li thiab tsis sterilized kho mob seev thiab nceb C.Glabrata nrog urinary los yog tso dej catheters. Feem ntau cov feem ntau ua kab mob los ntawm fungi hom C.Albicans, thiab cov thawj feeb ntawm ib tug me nyuam lub neej. Qhov no tshwm sim thaum lub sij hawm yog tau me nyuam, Yog hais tias leej niam chaw mos los yog populated nrog cov kab mob. Muaj kuj yog speculation uas C.Albicans nkag mus rau hauv tus me nyuam lub cev yog tseem nyob rau hauv lub embryo theem, vim hais tias cov nceb tau pheej tau pom nyob rau hauv amniotic kua. Yog hais tias ib tug poj niam nyob rau hauv zog yog ib feem ntawm lub me me feem pua ntawm cov neeg uas tsis muaj cov nceb, nws tus me nyuam thaum lub sij hawm thawj xyoo ntawm lub neej yuav tau txais lawv los ntawm lub txiv mis, cov khoom ua si thiab thiaj li nyob. Panic vim hais tias qhov no yog tsis tsim nyog, vim hais tias Candida, ib zaug nyob rau hauv lub cev ntawm nws tus tswv tsev, coj ntsiag to, txawm pab nws, tswj txoj kev loj hlob ntawm lwm yam pathogens.

Thaum lub fungi Candida kab mob yuav mob

Ib tug neeg yuav ua tau ib cov cab kuj los ntawm cov kab mob rau lub neej thaum uas seem kiag li noj qab nyob zoo. Yog ho nphav kiag ntawm lub genus Candida ua pathogenic tsuas yog thaum lawv loj hlob tau tawm ntawm kev tswj. Yog vim li cas:

- cev xeeb tub;

- ntau yam kab mob;

- exacerbation ntawm tus kab mob cov kab mob;

- hypothyroidism los yog vitamin tsis muaj peev xwm;

- long-term kev kho mob nrog tshuaj tua kab mob;

- corticosteroids;

- hormonal ntshawv siab.

Lub ntsiab yog vim li cas uas ua rau Candidiasis, ib tug tsis tshua muaj kev tiv thaiv. Qhov no mob no yuav tshwm sim nyob rau hauv ntau zaus, nrog rau cov neeg pluag noj haus, txom nyem nyob tej yam kev mob, heev nyuaj siab.

Nyob rau hauv tas li ntawd, cia li kev loj hlob ntawm fungi Candida tshwm sim thaum lub nram qab no concomitant kab mob:

- AIDS (los yog kab mob HIV);

- mob ntshav qab zib;

- kab mob ntsws;

- hnyuv kab mob;

- kab mob ntawm lub genitourinary system;

- hypothyroidism;

- Ib txhia ntshav kab mob;

- vaginosis.

pathogenicity yam

Qhov ntev ntawm lub pwm genus Candida tsuas yog 2-5 microns, li ntawd, lawv yuav pom tau tias tsuas nyob rau hauv ib tug tshuab kuaj kab mob. Cov dawb los yog yellowish-greyish plenochki uas loj hlob nyob rau hauv agar los yog cov quav hniav uas yog pom nyob rau cuam tshuam qhov chaw ntawm lub cev - qhov no yog tag nrho cov zos ntawm fungi, numbering pua pua txhiab tus neeg microorganisms. Ib zaug nyob rau tus tswv tsev kab, tus cwj pwm ntawm cov fungi ntawm lub genus Candida? Microbiologists txoj kev tshawb no pom tias txhua mushroom sib zog los tsim adhesion, uas yog, nyob ze rau niam txiv, ib tug tej zaum yuav hais tias, loj hlob mus rau hauv tib neeg epithelial hlwb. Nws microbes tswj qhov yooj yim dua qhov tsawg dua cov kev tiv thaiv ntawm lawv cov neeg raug, thiab lub siab nws endocrine ntshawv siab. Qhov tseem active ib feem ntawm lub clutch mushroom hom C.Albicans. Ib zaug rau cov qog ua kua week, nws adheres nyob rau hauv 100% ntawm cov neeg. Feem ntau cov passive mushroom hom C.Krusei. Nws yuav kho tsis tau, ces muaj yog tsis muaj kab mob. Pab fungi txeem nto cov nqaijrog thiab nto cov nqaijrog, ib co molecules, e.g., polysaccharides thiab glycoproteins, thiab molecules nyob rau hauv lub qhov ncauj qaub ncaug. Feem ntau, Candida yog glikogenofilami (glycogen zoo li no), li ntawd, feem ntau colonizes cov ntaub so ntswg uas nws muaj ntau yam, e.g., lub paum mucosa thiab lub qhov ncauj kab noj hniav. Nyob rau hauv cov kev tshwm sim ntawm cov poov xab fungi ntawm lub genus Candida nyob rau hauv ib tug smear coj los ntawm cov kabmob qhia ib tug siab yuav qhov muaj tseeb uas yuav pab kev ua yuam kev-free mob.

Thaum thawj zaug rau theem ntawm adhesion fungi yog cov poov xab daim ntawv no, tab sis sai sai lawm, txoj kev ua ntev filaments (hyphae), uas yog yooj yim los mus txeem mus rau hauv lub puas party hlwb thiab phagocytosis ntawm leukocytes nws tsawg.

Ntsaub thiab tus tswv, cab thaum lub sij hawm lawv lub neej nyob rau hauv tus tswv tsev kab cais ntau yam tshuaj lom:

- kandidotoksin (protein ua rau basophils thiab mast hlwb thiab yuav ua tau rau pseudo-teb);

- 6 hom ntawm tsawg molecular yuag toxins (nce vascular permeability, txo cov ntshav siab);

- lipid toxins (leukocyte ua zos tshua thiab ua rau kom cov tsos ntawm Granulation ntaub so ntswg).

Candidiasis nyob rau hauv cov me nyuam

Raws li sau tseg saum toj no, cov me nyuam mos kis tau kab mob Candida yog nyob rau hauv lub plab los yog thaum yug los thaum lub sij hawm tso cai ntawm lub yug kwj dej. Nyob rau hauv lub neej yav tom ntej, lub pwm yuav tau txais tus me nyuam nyob rau hauv lub qhov ncauj nrog ib tug tsis zoo kho lub txiv mis qhuav, rattles, nrog teats kis tus kab mob leej niam. Cov cim qhia tias tus me nyuam tau muaj ntawv cog lus qhov ncauj tawm, cov nram qab no:

- dawb, tsev cheese zoo li txheej ntawm tus nplaig, rau lub puab nto desenok thiab lub puab tsaig;

- moodiness;

- tsis kam ntawm cov zaub mov.

Yog tsis muaj kev kho mob, cov pwm tseem khom thiab tsis ntev nkaus li nyob rau ob daim di ncauj ntawm tus me nyuam.

Yog ho nphav kiag ntawm lub genus Candida nyob rau hauv lub gut dysbiosis manifest cov tsos mob xws li:

- raws plab;

- nkees;

- kub;

- tsis ntawm qhov ceeb thawj.

Zawv plab nyob rau hauv cov me nyuam mos yog txaus ntshai vim hais tias nws ua rau yus sai lub cev qhuav dej, yog li ib tug me nyuam mob yuav tsum tau pw tsev kho mob. Tsuas yog nyob rau hauv lub tsev kho mob muaj peev xwm muab nws nrog tus tsim nyog kho mob (nrog) los mus tiv thaiv cov kua tsis tau.

Nyob rau hauv tas li ntawd mus rau lub mob huam thiab lub qhov ncauj kab noj hniav, qhov ncauj tawm nyob rau hauv cov me nyuam mos tej zaum yuav tshwm sim ntawm daim tawv nqaij. Nyob rau hauv cov ntaub ntawv no, tsis muaj dawb, thiab liab me ntsis zoo li pob tw ntse. Tus me nyuam ua heev capricious raws li tej kev kov erosions ua nws kev txom nyem. Feem ntau cov feem ntau, cutaneous Candidiasis nyob rau hauv cov me nyuam mos zoo nkaus li nyob rau hauv lub folds rau ob txhais ceg, pob tw thiab puab tais. Preceded los ntawm lub pob tw ntse, ua nyob rau hauv pawj dhau lawm ntev, cov neeg pluag kev tu cev thiab tsis tsim nyog (hluavtaws, zawm dhau) cov khaub ncaws.

Kev kho mob ntawm infantile Candidiasis

Yog hais tias lub fungi ntawm lub genus Candida pathogenic txheej txheem pib nyob rau hauv lub qhov ncauj ntawm tus me nyuam, kev kho mob feem ntau yog nqa tawm zos. Nws muaj nyob rau hauv cov kev ntawm cov chaw uas muaj yog ib tug dawb zaj duab xis, tshwj xeeb npaj. Yav tas los, cov kws kho mob ntaus nqi mus rau grease tus me nyuam lub qhov ncauj nrog ntsuab xim. Qhov no tshuaj no zoo heev, tab sis qhuav txheej. Tam sim no siv "Akriderm", "Fukortsin" tshuaj ntawm borax nyob rau hauv lub glycerine.

Raws li kev tiv thaiv yog tsim nyog nyob rau hauv thawj lub hlis ntawm lub neej grudnichka rhaub mis thiab fwj, ntxuav rattles. Niam yuav tsum lis ua ntej pub mis noj tshuaj.

Thaum cov tsos mob ntawm dysbiosis pass quav grudnichka rau bakposev. Nws yog ntseeg hais tias cov fungi ntawm lub genus Candida nyob rau hauv cov quav nyob rau hauv cov me nyuam nyob rau hauv lub hnub nyoog ntawm 12 lub hlis tej zaum yuav tam sim no nyob rau hauv ntau tsis tshaj 103KOE / g, thiab ntau tshaj 12 lub hlis nyob rau hauv tus nqi ntawm cov 104KOE / g. Yog hais tias tus nqi yog ua zoo tshaj, muab cov tshuaj uas rov qab kho cov muaj thiab ntxiv dag zog rau lub cev.

Thaum Candidiasis daim tawv nqaij cuam tshuam qhov chaw ntawm lub noj tshuaj pleev smeared - nystatin, levorinovoy. Heev tseem ceeb rau tus da dej uas tus me nyuam mus rau hauv cov dej nrog qhov sib ntxiv ntawm broth succession, Calendula, chamomile. Tag nrho cov ntaub pua chaw thiab cov pawm yuav tsum hlau, thiab hloov pawm ntau txaus, tsis tos rau lawv mus ua kom tiav filling.

Yog hais tias cov kev kho mob tsis pab, koj tus me nyuam siv ib tug ntxiv kev soj ntsuam thiab muab noj txoj kev kho.

Candidiasis nyob rau hauv cov poj niam thiab cov txiv neej

Nyob rau hauv cov laus, Candida fungi yuav, zoo li cov me nyuam, kis tau rau lub qhov ncauj, daim tawv nqaij thiab cov hnyuv. Candidiasis yog manifested nyob rau hauv lub qhov ncauj caseous kov, exciting tus nplaig, cov pos hniav, palate, lub puab tsaig, thiab ib tug sab hauv sab nrog mob ncus. Tej zaum ulcerate txheej. Candidiasis ntawm daim tawv nqaij yus muaj los ntawm liab me ntsis nyob rau hauv qhov chaw ntawm cov kev taw qhia ntawm cov pwm (qhov tso, nyob rau hauv lub ob lub mis nyob rau hauv cov poj niam, nyob rau hauv lub puab tais, yam tsawg kawg nyob rau hauv lub hauv caug). Cov me ntsis khaus thiab tev, thaum khawb ulcerate. Tab sis feem ntau ntawm tag nrho cov neeg laus raug kev txom nyem los ntawm candida urinary kabmob. Cov poj niam ho nphav kiag Lodge nyob rau hauv qhov chaw mos thiab chaw mos, li ntawd, tus kab mob no yog hu ua vulvovaginitis. nws cov tsos mob nyob rau hauv thawj zaug rau theem raws li nram no:

- dawb (xws li qaub mis nyuj) paum paug;

- khaus, tsis dhau, tab sis nyob rau hauv tsis tooj, tom qab ntxuav lub loj hlob thiab nyob rau hauv thaum sawv ntxov;

- tsis kaj siab tsw ris tsho hauv qab;

- Mob thaum lub sij hawm com.

Qhov tseem qhia cov tsos mob - fungi ntawm lub genus Candida nyob rau hauv ib tug smear coj los ntawm qhov chaw mos.

Yog tsis muaj kev kho mob, cov tsos mob yog mob heev. , Mob tsis tau tsuas yog thaum lub sij hawm com, tab sis kuj nyob rau txhua tso zis, paum mucosa swells, ulcerate, paug yuav thicker.

Nyob rau hauv cov txiv neej, cov kab mob no yog hu ua Candida balanoposthitis. cov tsos mob:

- faib ntawm cheesy hom ntawm kev sib deev hloov khoom nruab nrog;

- khaus, mob thaum tso zis;

- mob com.

Nyob rau hauv tas li ntawd mus rau lub genitourinary system, Candida fungi yog cab rau sab lub cev ntawm cov neeg. Ntsia kab mob hu ua "onycha" thiab prinogtevogo menyuam - "paronychia". Cov ua rau cov kab mob yuav ua tau ib tug hangnail, ua ib tug manicure kis tus kab mob seev.

Analysis nyob rau fungi ntawm lub genus Candida

Candidiasis yog teem raws li nyob rau hauv cov kev tshwm sim ntawm cov kev tshawb fawb:

- ib tug smear los ntawm lub qhov ncauj kab noj hniav los yog koj qhov chaw mos;

- sowing;

- ELISA;

- PCR.

Nyob rau hauv tas li ntawd, tus kws kho mob tej zaum yuav txiav txim kom ntsuam xyuas ntawm cov zis thiab ntshav.

Yog hais tias koj npaj yuav siv ib tug kua ntswg los ntawm qhov chaw mos thiab / los yog zis, koj yuav tsis pub rau ntxuav nws, tab sis tsuas tso zis rau 2 teev ua ntej yuav noj cov smear, tsis pub. Yog hais tias koj npaj yuav siv ib tug kua ntswg ntawm lub qhov ncauj, nws yog txwv tsis pub mus ntxuav cov hniav.

Rau sowing siv quav, hnoos qeev, zis, scrapings los ntawm cov cuam tshuam qhov chaw ntawm daim tawv nqaij thiab qog ua kua week. Tom qab peb hnub, tau ib lo lus teb, yog los yog tsis muaj nyob rau hauv cov ntaub ntawv uas cov fungi ntawm lub genus Candida. Cai - yog tsis zoo. Yog hais tias kev ntsuam xyuas paub meej tias cov xub ntiag ntawm lub pwm, txiav txim nws hom thiab rhiab heev rau cov tshuaj.

ELISA tsom xam yog hu ua enzyme immunoassay. Nws yuav pab kom paub tias cov tshuaj mus rau lub pwm thiab khiav muaj zog ntawm tus txheej txheem. Material kev tshawb fawb rau cov EIA yog ib tug ntshav los ntawm ib tug hlab ntsha. Feem ntau, nws yog ua ua ke nrog bakposeve.

Nws yog suav hais tias yog feem ntau muaj tseeb PCR tsom xam ntawm dab tsi nws txhais tau hais tias polymer saw tshuaj tiv thaiv ntawm DNA molecules ntawm lub pwm. Nws detects cov xub ntiag ntawm lub pathogen txawm nyob rau hauv thawj zaug rau theem ntawm tus kab mob. Cov khoom siv rau lub PCR yog hnoos qeev feem, cov ntshav.

kev kho mob

Yog hais tias tus neeg mob yog muaj nyob fungi ntawm lub genus Candida, cov kev kho mob yog cov tshuaj. Hauv muab:

- "Fluconazole".

- "Nizoral".

- "Diflucan".

Externally siv tshuaj pleev:

- "clotrimazole".

- "Sertokanazol".

- "Miconazole".

- Taws tswm ciab nrog pumafitsinom thiab lwm yam txhais tau tias kom inhibit qhov kev loj hlob ntawm cov pwm. Lawv yuav tsum tau muab thiab antiinflammatory tshuaj pleev.

Kev kho mob ntawm cev xeeb tub cov poj niam yog nqa tawm tsuas yog lwm txhais tau tias. Tsuas yog nyob rau hauv ib tug ob peb tus neeg mob muab "Pumafitsin" hais lus.

Thaum Candidiasis urogenital huam yog cov kev kho mob ntawm tag nrho ob qho kev sib deev nrog ib tug neeg.

Nyob rau hauv tas li ntawd mus rau lub noj tshuaj yog kws vitamins thiab lwm yam txhais tau tias, txhawb lub cev.