Lub causative tus neeg saib xyuas ntawm diphtheria, nyob rau hauv cov tshuaj lub npe hu ua Corynebacterium diphtheriae, twb pom, thiab ces ntse zoo tu qab tso rau as xov xwm nyob rau hauv cov ntshiab kab lis kev cai 100 xyoo dhau los. Ces, tom qab ntau xyoo ntawm intensive kev tshawb no, nws tau tsim muaj lub luag hauj lwm nyob rau hauv qhov tshwm sim thiab kev loj hlob ntawm pathological kab mob. Qhov no tsuas yog sai tau tom qab tau txais daim ntawv ntawm ib lub taug uas tus kab mob ua. Nws ua rau tus tuag ntawm lub sim tsiaj, uas yog tsim los ntawm cov pathological cov tsos mob uas zoo sib xws rau cov neeg cai nyob rau hauv cov neeg mob uas mob qa hawj foob.
Diphtheria belongs rau lub genus Corynebacterium. Tab sis nws raug xa mus rau ib tug nyias muaj nyias ib pab pawg neeg ntawm coryneform kab mob. Nws yog ib nyuag nkhaus rods uas tau raug nthuav tawm los yog tapering rau hauv lub xaus. Lawv kuj muaj ib tug atypical division, raws li yog hais tias lawv yog lawm rau hauv ob qhov chaw, nrog ib tug txawv lwm qhov chaw nyob rau hauv daim ntawv ntawm cov Latin tsab ntawv V. Tab sis nyob rau hauv lub xeem smears yuav pom thiab raug rho tawm, sib nrug nyob sticks. Lub causative tus neeg saib xyuas ntawm diphtheria - comparatively loj cov kab mob, nws kav ntev npaum yog 8 microns. Lawv tsis muaj flagella, tus tiv thaiv kaus mom tsis tsim. Ib qho tseem ceeb khoom teejtug uas yog diphtheria bacilli yog lub peev xwm tsim tau muaj zog heev toxins.
Tag nrho cov hom ntawm cov Corynebacterium yog facultative anaerobes. Lawv xav tias zoo ob leeg nyob rau hauv lub xub ntiag ntawm oxygen, thiab tsis muaj nws. Resistant mus kom qhuav, txawm hais tias lawv muaj tsis muaj kev sib cav. Thaum raug tshav kub nyob rau hauv ib tug dawb huv kab lis kev cai ntawm 60 degrees, nws yuav crumble thaum lub sij hawm ib teev. Tab sis nyob rau hauv pathological cov ntaub ntawv, i.e. yog hais tias lawv muaj ib tug tiv thaiv protein, cov causative tus neeg saib xyuas ntawm diphtheria tau kom lawv cov muaj peev xwm mus nyob ntawm 40 mus rau 60 feeb. ntawm ib tug kub ntawm 90 degrees. Nrog hais txog qhov uas tsis muaj kub, tej dejnum ntxim rau cov kab mob yog cai. Nyob rau hauv ib txwm tsi ntsees ntawm disinfectants kab mob tuag sai sai.
Pathogen Diphtheria yog tseem yus muaj los ntawm loj polymorphism. Nws manifests nws tus kheej tsis tau tsuas yog nyob rau hauv kev hloov nyob rau hauv lub thickness ntawm cov tsis, tab sis kuj nyob rau hauv kev hloov rau hauv daim ntawv nws tus kheej. Nyob rau hauv smears paub qhov txawv branching, xov-li, segmented, o thiab hwj-zoo li tus sticks. Nyob rau hauv cov ntaub ntawv no, nyob rau ntawm lawv xaus rau ob sab tom qab 12 teev los ntawm thaum pib ntawm kab lis kev cai kev loj hlob muaj peev xwm yuav pom thooj kab mob yuav siv sij hawm rau hauv daim ntawv ntawm ib tug dumbbell. Cov thickenings ntawm tshwj xeeb xim kuaj thiaj hu ua grain-Babes Ernst (valyutina grain pawg).
Diphtheria yog saprophytes. Lawv xa mus rau cov neeg kab mob uas yog tas li nyob rau hauv kev xav tau ntawm cov organic teeb meem. Uas yog vim li cas lub siv kab lis kev cai tshaj tawm rau cov sau qoob rau ntawm no microbe nyob rau hauv txoj kev kuaj yuav tsum tau yuav muaj li ntawm amino acids. Qhov no tej zaum yuav cystine, alanine, methionine, valine. Xaiv nruab nrab rau coryneform kab mob yog cov uas muaj ntshiab, ntshav los yog ascites kua. Raws li nyob rau hauv no, nws twb xub tsim as nruab nrab Leffler, ua raws li los ntawm ib puag ncig thiab Tyndall Clauberg.