Medicament 'Azitsid', cov lus qhia rau kev siv, contraindications

Tshuaj tua kab mob broad-ntau tshuaj "Azitsid" yog hais txog ib tug pab pawg neeg ntawm macrolide (azitsidov). Qhov no ua los ntawm txoj kev ib siab concentration ntawm active tshuaj - azithromycin - qhov ntawm tus kab mob, bactericidal tsim kev tiv thaiv. Muaj yog ib tug high tshuaj ua si tiv thaiv Gram-zoo cov kab mob, thiab nyob rau lwm cov tes, nws twb tsis muaj ntxim rau cov kab-tsis zoo, uas yog resistant rau erythromycin.

"Azithromycin" yog resistant rau acidic ib puag ncig, yog li haum ntawm cov tshuaj los ntawm tus mob huam tshwm sim. Drug nce mus txog ntau tshaj plaws nyob rau hauv concentration cov ntshav ntshav tom qab 3 teev nws muaj ib tug mob loj tsawv bioavailability ntawm 37%. Nws yuav tsum tau muab sau tseg ib tug zoo kev pom rau hauv lub urogenital nruab nrog cev thiab cov nqaij nyob rau hauv lub ua pa ib ntsuj av tau, daim tawv nqaij thiab nqaij mos npaj "Azitsid" cov lus qhia rau kev siv qhia txog qhov no uas tsis muaj ruaj rau cov nqaijrog ntawm cov ntshav ntshav. "Azithromycin" yog xa mus rau lub siab concentration ntawm phagocytes kab mob qhov chaw, thiab yog tso tawm nyob rau hauv tus txheej txheem ntawm phagocytosis, tsis tas yuav ua tej yam tsis zoo rau lawv.

Tsis pub dhau ib lub lim tiam, cov tshuaj yuav tsum tau muab khaws cia nyob rau hauv siab concentration nyob rau hauv lub foci ntawm tus kab mob, tso tawm kom pom lub active muaj nyob rau hauv theem 2, qhov no tso cai rau kom muab cov tshuaj ib hnub ib zaug.

Inflammatory kab mob ntawm txawv cim yog cov indications rau kev kho mob nrog "Azitsid" cov lus qhia rau kev siv los kho lawv xws li cov kab mob, uas yog tshwm sim los ntawm kab mob rhiab mus rau yeeb tshuaj. Qhov no muaj xws li cov nram qab no kab mob:

- urogenital;

- lub Upper pa ib ntsuj av tau, e.g., tonsillitis, tonsillitis, otitis xov xwm , thiab lwm yam thiab otolaryngology ;.

- tsawg pa ib ntsuj av tau, xws li SARS;

- daim tawv nqaij thiab nqaij mos (impetigo, theem nrab dermatoses);

- thawj zaug rau theem ntawm Lyme kab mob;

- duodenal rwj kab mob, pais plab pathology.

Nyob rau hauv lub sij hawm ntawm kev kho mob yog tsim nyog los ua raws li cov dosing regimen "Azitsid" yeeb tshuaj, phau ntawv qhia xav noj cov tshuaj tom qab ib tug noj mov ib zaug ib hnub twg rau ntawm koob tshuaj tshuaj rau ib tug neeg zus.

Los ntawm ib co systems ntawm lub cev tshwm sim muaj tshwm sim raws li ib tug tshwm sim uas tau txais "Azitsid" npaj qhia piav tau tsis zoo ces cov me nyuam thiab urinary system, nyob rau hauv daim ntawv ntawm cov kev tsis haum los yog dermatological tshua. Nyob rau hauv cov me nyuam, kev kho mob tej zaum yuav ua rau khaus, conjunctivitis thiab urticaria.

Loj lub raum thiab hepatic tsis ua hauj lwm pom tau hais tias ua discontinuation ntawm kev kho mob siv yeeb tshuaj "Azitsid" phau ntawv qhia hais txog mus rau ob peb contraindications nrog hwm rau lub cuab tam:

- cov me nyuam muaj hnub nyoog nyob rau hauv 3 hlet los yog uas tsawg tshaj li 25 kg:

- High rhiab heev mus rau yeeb tshuaj:

- High rhiab heev rau macrolide tshuaj tua kab mob.

Kev Kho Mob txhais tau tias "Azitsid" thaum lub sij hawm cev xeeb tub yog ua tau, tiam sis tsuas yog nyob rau hauv cov ntaub ntawv ntawm superiority pab los ntawm kev noj cov tshuaj no rau cov poj niam nyob rau hauv lub peev xwm uas yuav muaj rau tus me nyuam.

Nrog ib tug overdose ntawm cov tshuaj "Azitsid" pom tau tib tsos mob li hais tias ntawm lub sab los, tab sis lawv yuav tshwm sim nyob rau hauv amplified daim ntawv. Qhov no tej zaum yuav ntuav, mob xeev siab thiab raws plab, tau ib ntus tsis hnov lus. Raws li kev kho mob coj tshuab txais hluav ncaig, pais plab lavage thiab lwm yam symptomatic txoj kev kho.

Ua ntej lub sij hawm teem ntawm cov tshuaj "Azitsid" raws li ib tug tshuaj yuav tsum tau them rau kev mloog kom nws sis raug zoo nrog lwm yam tshuaj. Ua ntej ntawm tag nrho cov, nws yuav tiv thaiv ib tug ua tau overdose, uas tshwm sim vim hais tias ntawm lub kev sib nrig sib qhov cuab lub zog ntawm tej nyiaj. Piv txwv li, ua ntawv thov "Azitsid" ua ke nrog digoxin cai nce concentration ntawm lub yav tas rau hauv lub cev thiab chloramphenicol thiab tetracycline txhim khu qhov kev txiav txim ntawm azithromycin. Zoo ib yam li tus neeg mob cov tshuaj cov kev sib tshuam yog piav nyob rau hauv kom meej nyob rau hauv cov lus qhia mus rau yeeb tshuaj.

Qhov siab tshaj plaws txee lub neej ntawm cov tshuaj yog 2 xyoo, nws yog muab tawm hauv lub ncav cuag ntawm cov me nyuam thiab ib qhov chaw txias.