"Dorzopt" (qhov muag dauv): daim ntawv qhia, kev txheeb xyuas, analogs

GLAUCOMA - ib tug es loj pab pawg neeg ntawm qhov muag cov kab mob, uas yog yus muaj los ntawm periodic los yog tas mus li nce nyob rau hauv intraocular siab nrog tom ntej txoj kev loj hlob tsis zoo, ua optic Atrophy thiab ib tug txo nyob rau hauv nrig txog kev pom pom tseeb tseeb.

Rau cov kev kho mob ntawm cov kab mob siv ntau tshuaj. Feem ntau cov tshuaj yog "Dorzopt" (qhov muag dauv). Consumer xyuas, cov lus qhia rau kev siv cov tshuaj no yuav tsum tau tham hauv qab no.

Cov thiab muaj pes tsawg leeg

Yuav ua li cas tshuaj muaj ib tug yeeb tshuaj "Dorzopt" (qhov muag dauv)? Lub active feem ntawm cov tshuaj yog dorzolamide (raws li hydrochloride). Tsis tas li ntawd lub medicament muaj cov nram qab no koom haum pab tshuaj: Benzalkonium chloride, gietelloza, mannitol, sodium hydroxide, citric acid monohydrate, purified dej.

Saib khoom ua nyob rau hauv polyethylene vials nrog 5 ml dropper nozzle.

pharmacodynamics

Yuav ua li cas yog qhov muag dauv "Dorzopt"? Phau Ntawv Qhia hais tias qhov cuab tam yog ib lub zos carbonic anhydrase inhibitor. Nws muaj ib tug depressing ntxim rau cov intraocular kua secretion thiab cheeb qhov uas cov tsim ntawm hydrogen carbonate thiab dej tsis muaj zog txog cov kev hloov thiab sodium.

Qhov no tshuaj tsis ua miosis los yog hmo ntuj dig muag, raws li zoo raws li lub spasm ntawm kev pab.

tshuaj

seb cov tshuaj yog absorbed, "Dorzopt" (qhov muag dauv)? Haum ntawm cov tshuaj yuav siv sij hawm qhov chaw los ntawm cov cornea thiab los ntawm cov povtseg thiab sclera. tshuaj mauj haum nqi yog heev tsawg.

Ib zaug nyob rau hauv cov hlab ntsha, cov tshuaj active ingredient sai penetrates mus rau hauv cov ntshav liab nrog ib tug high school cov ntsiab lus ntawm carbonic anhydrase 2.

Kev sib txuas lus nrog ntshav cov nqaijrog tshwm sim los ntawm 33%. Cov tshuaj no yog hloov dua siab tshiab rau N-dezetilirovanny metabolite, uas yog tsis heev kom nquag plias tiv thaiv carbonic anhydrase 2, tab sis muaj peev xwm sawv ntawm thaiv cov hlab ib carbonic anhydrase.

Heev siv ntawm cov tshuaj ua rau nws cia hnab khib nyob rau hauv erythrocytes.

Tso tawm cov tshuaj los ntawm ob lub raum. Lawv tshem tawm muaj 2 tshem tawm theem: ceev thiab qeeb. Cov yav tas yog tshwm sim los ntawm lub tsheb txhob sibtsoo tso tawm ntawm lub active tivthaiv ntawm cov ntshav liab.

ib nrab-lub neej sij hawm ntawm hais txog 4 lub hlis.

zaj lus tim khawv

Thaum prescribers "Dorzopt"? Qhov muag dauv zoo heev nyob rau hauv cov kev kho mob ntawm kom intraocular siab nyob rau hauv cov neeg uas muaj ocular tawg los yog qhib-pseudoexfoliative glaucoma (xws li theem nrab).

Contraindications

Nyob rau hauv dab tsi ntau, koj muaj peev xwm siv tsis tau cov tshuaj "Dorzopt"? Qhov muag dauv tsis kho rau:

• hyperchloraemic acidosis;
• Npau taws me ntsis rau cov constituent ntsiab;
• mob loj heev raum mob;
• raws li ib tug me;
• nyob rau hauv lub lactation lub sij hawm.

Nrog huab ceev faj yuav tsum raug siv qhov cuab tam:

• mob ntshav qab zib;
• cov neeg mob uas hepatic puas;
• cov neeg uas muaj me me ceev ntawm lub cornea endothelium hlwb ntawm lub qhov muag (ntawm lub high school yuav corneal edema).

dosing

Muab ntshai lub cuab tam rau cov kev kho mob ntawm lub qhov muag cov kab mob tsuas muaj ib tug nqaim specialist tom qab ceev faj kev soj ntsuam ntawm tus neeg mob. Faus formulation desirably ib tug nco rau hauv lub conjunctival sac ntawm peb lub sij hawm ib hnub.

Nrog ua ke nrog cov tshuaj nrog beta-blockers tshuaj pleev tshuaj rau siv ib tug nco ib hnub ob zaug.

Yog hais tias ocular kab mob kev kho muaj xws li ob peb ophthalmic agents, lub luv nruab nrab ntawm lawv instillation yuav tsum muaj tsawg kawg yog kaum feeb.

phiv

Yog hais tias koj siv qhov muag dauv "Dorzopt" Cov nram qab no lub zos tshua yuav tsim nyob rau hauv cov neeg mob:

• Khaus thiab kub nov ntawm nqaij tawv nyob rau hauv lub ob lub qhov muag, conjunctivitis, paresthesia, daim tawv muag edema, tearing, blepharitis, impaired clarity uas tsis pom kev, photophobia thiab ces dag punctate keratitis.
• Heev tsis tshua tiv thaiv daim ntawv thov ntawm cov tshuaj no yog: iridocyclitis, nce lub thickness ntawm lub cornea, koob tshuaj tiv thaiv, hypotension qhov muag thiab retinal detachment tom qab antiglaukomatoznyh hauj lwm.

Mauj kev phiv:

• zoo nkaus li xeev siab, ntsim saj nyob rau hauv lub qhov ncauj, nefrourolitiaza txoj kev loj hlob, qaug zog, migraine, malignant exudative erythema multiforme, tshuaj lom epidermal necrolysis, aplastic anemia, daim tawv nqaij ua pob liab vog thiab agranulocytosis.

tus neeg mob ntawm overdose

Yuav ua li cas cov tsos mob tshwm sim thaum uas siv cov "Dorzopt" high koob tshuaj ntawm cov tshuaj? Eyedrops, analogs uas muaj qhia hauv qab no, yuav pab txhawb:

• acidosis txoj kev loj hlob;
• kev cuam tshuam ntawm cov dej electrolyte tshuav nyiaj li cas;
• Cns phiv.

Rau cov kev kho mob ntawm xws tej yam kev mob ua hauj lwm symptomatically, nrog los ntawm cov tswj lub theem ntawm electrolytes thiab cov ntshav pH.

tshuaj cov kev sib tshuam

• Thaum ua ke nrog cov tshuaj antiglaucoma agents (beta-blockers, "dipivefrin", "pilocarpine", "Carbachol") amplifies nws cov nyhuv.
• Nrog "acetazolamide" tsub kom qhov uas yuav ntawm muaj quag kev phiv.
• Nrog loj noj tshuaj npaum cas ntawm acetylsalicylic acid tsub kom lub toxicity ntawm cov tshuaj.

tej tswv yim pom zoo

Kev siv cov multidose vials tej zaum yuav ua txoj kev loj hlob ntawm cov kab mob keratitis. Qhov no yog vim inadvertent kis ntawm lawv txheem.

Thaum lub sij hawm kev kho mob "Dorzoptom" yuav tsum tsis txhob siv lo ntsiab muag li benzalkonium chloride yuav ua tau tshuaj lom thiab ua voos rau lub qhov muag.

Analogs thiab tshuaj nqi

Hloov qhov suav hais tias cov tshuaj rau hauv lub qhov muag yuav ua tau los ntawm txhais tau tias xws li "Trusopt" thiab "Floksal". Nqe ntawm cov tshuaj yog hais txog 350 rubles.

neeg xyuas

Tu siab, cov neeg xyuas txog cov tshuaj "Dorzopt" tsis tshua muaj. Ntawm cov ntsiab zoo ntawm cov tshuaj no ceeb toom xws li txaus thiab hauj lwm zoo. Txawm li cas los, ib co kev pab yog muaj kev txhawj xeeb, lub zos thiab mauj kev phiv tshuaj uas tshwm sim thaum lub sij hawm kev kho mob nrog rau. Nyob rau hauv no hais txog, cov kws txawj yuav pom zoo kom siv ntawm cov tshuaj nyob rau hauv lub npe "Dorzopt Plus".

Eyedrops hais saum toj no muaj xws li xws ntxiv tshuaj, xws li timolol. Nws txhawb nqa lub kua intraocular kua.