Cov tshuaj "Prosulpin": phau ntawv qhia, kev xyuas thiab analogues

Tshuaj "Prosulpin cov lus qhia rau kev siv yog positioned raws li ib tug haib antipsychotic tshuaj uas yog siv nyob rau hauv cov kev kho mob los ntawm ntau yam mob ntawm poob siab system thiab lwm yam kab mob. Yog xav paub ntxiv txog cov saum toj no kev npaj, nyeem rau.

Luv hauj lwm ntawm cov kev npaj

Qhov no tshuaj belongs rau cov pab pawg neeg ntawm pawg -benzenamine. Nyob rau hauv lwm txoj kev, peb yuav hais tias yog ib tug raug antipsychotic tshuaj "Prosulpin". Guest kws txawj taw tes kom paub tias qhov kev txiav txim yog aimed ntawm thaiv cov hlab dopamine receptors (D2i D3). Vim lub aforementioned antipsychotic tshuaj ua ib tug kho nyhuv.

50 los yog 200 mg ntawm ib ntsiav tshuaj muaj sulpiride "Prosulpin" kev npaj.

Sab los thaum peb noj lub tshuaj, ntawm chav kawm, tshwm sim nyob rau hauv tej rooj plaub. Yog li ntawd, ib tug neeg mob thaum lub sij hawm hauv chav kawm ntawm kev kho saum toj no antipsychotic yuav tsum muaj nyob rau hauv nruj kho mob saib xyuas.

Qhov no tshuaj muaj ob peb cov ntaub ntawv. Nws yog muaj nyob rau hauv cov ntsiav tshuaj daim ntawv thiab nyob rau hauv daim ntawv ntawm cov tshuaj, ib tug tov rau intramuscular thawj coj thiab cov kua rau haus.

Cov tshuaj yuav tsum tau muab cia rau hauv ib txwm chav tsev kub, tab sis tsis muaj ntau tshaj li 25 degrees Celsius. Qhov chaw yuav tsum zoo tiv thaiv los ntawm lub teeb thiab ya raws. Ze li ntawm ob xyoos ntawm txee lub neej "Prosulpin" tshuaj. Analogues nws tsis yog nyuaj mus nrhiav. Tshuaj rau lub lag luam ntau ntau yam ntawm tej yam saum toj no-hais cov tshuaj.

Lub pharmacological kev txiav txim ntawm lub aforementioned kho neeg sawv cev

Tshuaj "Prosulpin" uas nws yees duab yog muab hauv qab no, yog ib qho antipsychotic neeg sawv cev uas yog ib tug neuroleptic. sulpiride tshuaj vim thaiv cov hlab ntawm dopamine receptors nyob rau hauv tuberoinfudibulyarnoy cheeb tsam txhawb ib tug tseem ceeb nce nyob rau hauv prolactin theem. Nws yuav tsum tau muab sau tseg tias nyob rau hauv cov kab 60-80% degree txawv thaiv cov hlab dopamine receptors.

Cov yav tas txawv sufficiently siab kev zoo sib thooj rau cov benzamide, uas yog cov yam ntxwv ntawm xws li ib tug feature li bifazicheskoe ntxim rau cov neurotransmitter dopamine system. Nyob rau hauv tas li ntawd, lawv thaiv lub nce nyob rau synaptic dopamine synthesis cheeb tsam, i.e. thaiv kev presynaptic pib receptor D2 D3.

Nws yuav tsum tau muab sau tseg tias saum toj no formulation yog mob me me neuroleptic kev ua si. Cov yav tas yog ua ke nrog lwm tus timoanalepticheskim thiab stimulating kev txiav txim ntawm lub cuab tam.

Qhov saum toj no tshuaj muaj cov nram qab pharmacological los:

• antiemetics (dopamine receptor blockade yog ua txhais ntuav center tsam);
• antidepressant;
• antipsychotic.

Sulpiride qhia tau hais tias antidepressant los ntawm koob tshuaj mus rau 600 mg. Saum toj no no kev twb tau cai antipsychotic los ntawm cov tshuaj no rau ntawm lub cev.

Nyob rau hauv tas li ntawd, cov tshuaj "Prosulpin" qhia hais nws ua ib tug xim ntxim rau cov hypothalamus, cov tsos mob ntawm pais plab rwj thiab gastroduodenitis. Yog li suppressed siab excitation chaw ntawm lub sympathetic lub paj hlwb, pab txoj kev ntshav mov rau lub plab, ceev loj hlob ntawm Granulation ntaub so ntswg, cov txheej txheem ntawm hnoos qeev secretion nyob rau hauv lub plab, yog tsim regenerated epithelium, loj hlob ntawm cov hlab ntsha pab cov ntaub so ntswg.

Leej twg yuav tsum noj cov tshuaj no tshuaj?

Yuav ua li cas yog tshuaj "Prosulpin" indications rau siv? Rau kho cov hom phiaj, cov saum toj no cov tshuaj siv nyob rau hauv xws kab mob:

• psychosomatic kab mob;
• kev nyuaj siab ulcers ntawm lub digestive ib ntsuj av tau;
• symptomatic ulcers;
• gastroduodenitis;
• plab lub rwj;
• chim siab plob tsis so tswj (nyuv);
• tshuaj ulcers;
• nonspecific ulcerative mob plab;
• Kev nyuaj siab ntau etymology;
• neuroses;
• reactive kev nyuaj siab;
• dysphoric teeb meem;
• schizophrenia;
• mob puas siab puas ntsws ;
• migraine;
• mob hlwb kev ntshawv siab;
• kiv tauv hau sib txawv etymology (vestibular neuritis, vertebrobasilar insufficiency, basilar, Meniere tus kab mob, otitis xov xwm).

Tshuaj "Prosulpin" cov lus qhia rau kev siv muaj mus thov rau cov kev kho mob ntawm kev coj xeeb ceem mob thiab psychoses nyob rau hauv cov tub ntxhais cov neeg mob, piv txwv li cov me nyuam. Qhov no mob xws li self-mutilation, ntxhov siab, stereotypes. Tsis tas li ntawd cov tshuaj "Prosulpin" cov lus qhia rau kev siv insistently tswv yim rau siv raws li ib feem ntawm ib lub chav kawm ntawm txoj kev kho ntawm infantile tsi txawj has lug. Qhov cuab yeej no yog siv los kho cov tub ntxhais cov neeg mob muaj hnub nyoog 6 xyoo.

Contraindications rau kev siv ntawm lub aforementioned tshuaj

Tshuaj "Prosulpin cov lus qhia rau kev siv tsis pom zoo yog hais tias tus neeg mob muaj cov tsos mob li nram qab no cov kab mob:

• npau taws me ntsis mus rau yeeb tshuaj;
• hyperprolactinemia;
• prolaktinzavisimye hlav (cancer ntawm lub mis, pituitary prolactinoma);
• mus ob peb vas kev ntshawv siab;
• mob lom cov dej qab zib uas muaj haus dej haus cawv;
• txhoj puab heev coj tus cwj pwm;
• pheochromocytoma;
• Mob lom los ntawm cov tshuaj los yog cov tshuaj tsaug zog tshuaj;
• manic psychosis.

Tag nrho cov kas no nruj contraindications. Tsis tas li ntawd cov tshuaj "Prosulpin" cov lus qhia rau kev siv txwv hlo tsis pub muab rau cov poj niam uas lub mis-pub lawv tus me nyuam, cov me nyuam nyob rau hauv lub hnub nyoog ntawm 18 (rau 200 mg tshuaj), cov tub ntxhais cov neeg mob mus txog 6 xyoo (50 mg tshuaj).

Nyob rau hauv tas li ntawd, nws yuav tsum tau nco ntsoov hais tias, yog tseem undesirable siv cov tshuaj "Prosulpin" congenital tsis muaj peev xwm ntawm lactose, qabzib-galactose malabsorption, lactose intolerance. Contraindications rau kev siv ntawm cov saum toj no kho cov neeg ua hauj kuj thov tau mus rau cev xeeb tub cov poj niam. Siv nws rau tej neeg mob yog tso cai tsuas yog hais tias tus yuav tsum kev pab cuam ntawm cov tshuaj yuav tsum tau npaum li cas siab tshaj lub peev xwm uas yuav muaj rau lub fetus los ntawm nws.

phiv

Thaum tau txais "Prosulpin" npaj (phau ntawv qhia no), tej zaum koj yuav muaj kev ib co mob tshwm sim:

• nyob rau ib feem ntawm lub endocrine system - galactorrhea, dysmenorrhea, amenorrhea, frigidity, impotence;
• los ntawm paj - tshuaj kom tsaug zog, tshee, kiv taub hau, thaum ntxov dyskinesia, extrapyramidal syndrome, somnolence, akinesia nrog npag hypertonicity, akathisia, lub cev muaj zog excitation;
• kom nyob rau hauv cov kev ua ntawm enzymes (los ntawm lub plab zom mov);
• hemolytic anemia, leukocytosis, aplastic anemia, granulocytosis, purpura, thrombocytopenic tshwm sim nyob rau ntau dua koob tshuaj "Prosulpin" npaj (los ntawm qhov kev txiav txim ntawm cov ntshav thiab cov qog tshuab);
• tachycardia, orthostatic hypotension, tsis los yog nce ntshav siab, lengthening lub luv QT, nyob rau hauv tej rooj plaub txoj kev loj hlob ntawm txaus ntshai kab mob xws li torsade des pointes syndrome (ntawm lub plawv thiab nws cov system).

Tsis tas li ntawd ua lwm yam kev phiv cov tshuaj no. Tshuaj "Prosulpin" (qhia cov lus teb los ntawm cov kws kho mob thiab cov neeg mob cov lus teb ua tim khawv rau qhov no) yuav ntxias xws unpleasant tshwm sim raws li tardive dyskinesia, uas yog yus cov tsis zoo taw ntawm lub ntsej muag los sis tus nplaig (nrog ib tug ntev kho cov hoob kawm neuroleptics tag nrho cov pab pawg), hyperthermia. Kws txawj ceeb toom hais tias nyob rau hauv lub caij nyoog kawg no cov ntaub ntawv yog tshwj xeeb tshaj yog ib qho tseem ceeb nyob rau hauv lub sij hawm mus rho cov saum toj no txhais tau tias, txij thaum lub kub sawv tej zaum yuav qhia ntawm tej kab mob txaus ntshai xws li neuroleptic phem syndrome.

Koj qhov hnyav nce, nce tawm hws, daim tawv nqaij ua pob liab vog thiab khaus - tag nrho cov sab los kuj ua tshuaj "Prosulpin". Cov lus qhia, cov lus los ntawm cov kws txawj pom zoo kom nyob rau hauv xws li mob kom tsis txhob noj cov tshuaj saum toj no thiab nrhiav kev tam sim ntawd kws kho mob kom tau kev pab thiab tswv yim.

Siv lub sij hawm uas cev xeeb tub saum toj no lub tshuaj neeg sawv cev

Teratogenicity ntawm cov tshuaj tsis tau pom raws li ib tug tshwm sim ntawm cov tsiaj thwmsim. Ib txhia poj niam uas tau siv cov tshuaj thaum lub sij hawm koj cev xeeb tub, thiab ho tsis saib lub saum toj no-hais nyhuv. Tab sis cov neeg mob tau txais tsawg koob nruj me ntsis txhais tau tias "Prosulpin". Cov lus qhia rau kev siv, tiag tiag kws txawj tsis muaj kev qhia txog cov kev siv ntawm ib tug ntau dua tus nqi ntawm ib yam khoom xws li sulpiride. Muaj kuj yog tsis muaj ntaub ntawv nyob rau hauv cov nyhuv uas cov aforementioned formulation rau txoj kev loj hlob ntawm lub me nyuam hauv plab lub hlwb.

Raws li ib tug yuam cov kws txawj tsis qhia siv cov tshuaj no rau cov poj niam nyob rau hauv lub xeev. Txawm tias nyob rau hauv tej rooj plaub, tseem tso cai rau kev kho mob ntawm cov saum toj no-hais kev npaj ntawm cov neeg mob, lawv cia siab tias ib tug me nyuam, tab sis nruj me ntsis nyob rau hauv tsawg heev koob tshuaj.

Kws txawj nco ntsoov tias yog hais tias tus niam yog tau txais neuroleptics txoj kev kho ntev lub sij hawm, tus me nyuam mos noj muaj teeb meem nrog cov hnyuv ua hauj lwm (xws li tsam plab).

Yog hais tias ib tug poj niam siv cov tshuaj thaum lub sij hawm lub sij hawm ua ntej rau tus me nyuam, cov tswj nws lub cev thiab txoj kev loj hlob ntawm lub fetus los ntawm ib tug kws kho mob yog yuav tsum tau.

Nws yuav tsum tau nco ntsoov hais tias uas kis tau mus rau hauv niam cov kua mis tshuaj "Prosulpin". Cov lus qhia rau kev siv, tiag tiag kws txawj tsis pom zoo kom noj nws thaum lub sij hawm lactation.

Yuav ua li cas mus noj cov tshuaj "Prosulpin"?

Phau Ntawv Qhia muaj cov neeg mob siv cov saum toj no antipsychotic txhua 8 teev rau ib tug hluas cov ntsiav tshuaj. Yog tsis pom zoo kom noj cov tshuaj tom qab 16,00, raws li nws cov kev ua si yog heev tsub kom lub sij hawm no. Nws yuav tsum tau muab sau tseg tias siv tsis hais txog ntawm rooj noj mov thiab ntxuav nrog ib tug txaus tus nqi ntawm ib tug kua npaj "Prosulpin".

Ntsiav tshuaj uas muaj 200 mg ntawm sulpiride, yog txais rau hauv lub mob cov tsos mob schizophrenia, delirious psychosis thiab kev nyuaj siab. Cov tshuaj yuav tsum noj nyob rau hauv faib koob tshuaj. Nws siab tshaj plaws txhua txhua hnub koob tshuaj yog 100 mg, los yog hais txog 5 tshuaj.

Ntsiav tshuaj, uas muaj xws li 50 mg ntawm sulpiride, muaj kev qhia ntawv rau noj, yog hais tias tus neeg mob muaj cov tsos mob ntawm neurosis, ntxhov siab vim. Tsis pub dhau 4 lub lis piam, cov neeg mob yuav tsum tau noj ib tug tsawg kawg nkaus ntawm ib tug thiab ib tug tshaj plaws ntawm 3 ntsiav tshuaj ib hnub twg.

Tsis tas li ntawd, cov tshuaj yuav tsum tau noj rau cov me nyuam uas muaj teebmeem tus cwj pwm muaj teeb meem. Lub hnub nyoog ntawm xws cov neeg mob yuav tsum nco ntsoov muaj ntau tshaj li 6 xyoo. Qhov siab tshaj plaws txhua txhua hnub koob tshuaj rau cov neeg mob nyob rau hauv pawg no yog los ntawm 5 mus rau 10 mg rau ib 10 kg lub cev hnyav.

overdose

Phau ntawv ntawd hais tias overdose sulpiride ntaub ntawv no xwb. Cov nram qab no cov tsos mob tej zaum yuav muaj cai nyob rau hauv tus mob no nyob rau hauv ib tug neeg mob:

• tus nplaig protrusion;
• dyskinesia nrog spasmodic torticollis;
• qhov muag plooj tsis pom kev;
• qhov ncauj qhuav;
• tau txoj kev loj hlob ntawm NSAs;
• extrapyramidal cov tsos mob;
• nce tawm hws;
• xeev siab;
• tshuaj kom tsaug zog;
• gynecomastia;
• Parkinson tus kab mob;
• kom nyob rau hauv cov ntshav siab.

Kev kho mob ntawm lub saum toj no lub xeev ntawm tus neeg mob yog nqa tawm raws li nram no:

• ntxuav lub plab ntawm tus neeg mob;
• taw los ntawm lub tshuab txais carbon;
• ib tug systematic txoj kev kho.

Yog hais tias tsim nyog, nyob rau hauv loj heev zaum, tus kws kho mob yuav muab tshuaj rau ntxiv manipulation, xws li diuresis Txoj kev lis ntshav dlaws ntawm alkali los yog saib xyuas tseem ceeb heev lub cev functions.

Nws yuav tsum tau muab sau tseg hais tias qhov no npaj muab tej nyob rau hauv hemodialysis.

Tej yam pawg ntawm cov neeg mob yuav tsum tau tshwj xeeb kev ceev faj thaum uas siv cov "Prosulpin" tshuaj. Qhov no siv feem ntau rau cov poj niam nrog cov lus sij hawm, cov neeg mob uas muaj mob loj hypotension thiab tawg.

Nws tseem ceeb heev rau cov neeg mob uas tau qaug dab peg yam ua ntej electrophysiological thiab soj ntsuam kev xeem. Nws yuav tsum tau nco ntsoov tias cov tshuaj "Prosulpin" lowers tus Harbor rau qaug dab peg kev ua si.

Tsis tas li ntawd, thaum tsav tsheb thauj yuav tsum tau kev pab tshwj xeeb thaum lub sij hawm kev kho mob nrog rau cov saum toj no cov tshuaj. Nws tseem ceeb heev kom tsis txhob ua tej yam uas yuav tsum tau sai psychomotor tshua thiab siab concentration.

Sis nrog rau lwm cov tshuaj cov neeg ua hauj

Cov lus qhia yog tsis nruj me ntsis xav kom cov saum toj no-hais tshuaj nyob rau hauv lub neej coj txoj kev kho nrog levodopa. Lub ob active tshuaj yog antagonists. Yog hais tias ib tug neeg mob, uas suffers los ntawm Parkinson tus kab mob, yuav siv sij hawm levodopa, tus kws kho mob yog tus neeg saib xyuas yuav tsum tau xaiv hais tias muaj ib tug tsawg heev extrapyramidal los.

Arrhythmias xws li torsades de pointes tej zaum yuav tshwm sim los ntawm ib tug ua ke "Prosulpin" tshuaj nrog:

• antiarrhythmic tshuaj, uas nyob rau hauv cov chav kawm ntawv Ia (tshuaj "Dizopiramid" "quinidine");
• tshuaj "pimozide," "Haloperidol", "thioridazine" "Cisapride", "Pentamidine" imipraminovymi antidepressants;
• antiarrhythmic tshuaj uas muaj nyob rau hauv lub thib peb hauv chav kawm ntawv (txhais tau tias "Sotalol", "Kakamiodaron");
• cov tshuaj uas ua rau cov tsos mob ntawm cov kab mob xws li bradycardia (beta-blockers, calcium channel blockers);
• cov tshuaj uas ua rau kom cov tsos ntawm cov cim ntawm hypokalemia (cov tshuaj ntaus cev uas yog stimulatory, hypokalemic diuretics, tetracosactide, glucocorticoids);
• dopamine antagonists (antiparkinson): "apomorphine", "Amantadine" "Lisuride", "Ropinirole", "Entacapone" "Bromocriptine", "selegiline" "Pramipexole" "Piribedil");
• antipsychotic tshuaj uas muaj peev xwm ua rau cov tsos mob ntawm torsades de pointes ( "Chlorpromazine" "Amisulpride," "Tsiamemazin" "pimozide," "Droperidol" "levomepromazina" "tiapride," "Sertindole" "Veraliprid" "Sulpiride") ;
• tshuaj uas muaj lithium (tus tom kawg considerably tsub kom kev pheej hmoo ntawm extrapyramidal mob).

Tsis tas li ntawd, nyob rau hauv txhua rooj plaub, cov tshuaj "Prosulpin" yuav tsum tsis txhob yuav siv tau nrog rau haus dej haus cawv. Xeem potentiates lub sedative nyhuv ntawm neuroleptics.

Nyob rau hauv tas li ntawd, yog hais tias peb coj lub saum toj no-hais tshuaj nyob rau hauv ua ke nrog nrog centrally stimulating tshuaj (anti-asthmatics, anorectics), tus neeg mob tej zaum yuav muaj cov tsos mob ntawm muaj zog excitation, nervousness, ntxhov siab vim, kev txhawj xeeb.

Nws yuav tsum tau nco ntsoov tias antipsychotic tshuaj txo cov theem ntawm cov hauj lwm zoo ntawm ropinirole.

Hloov "Prosulpin" kho neeg sawv cev

Analogs ntawm lub saum toj no antipsychotic:

• "Betamak T100";
• "Vero Sulpiride";
• "Betamax T50";
• "Depral";
• "Betamax";
• "Lub dogma ntawm";
• "Betamax T200";
• "Sulpiride";
• "Eglonil";
• "Sulpiril";
• "Eglek".

Tab sis hloov tsis tau ua ntej kev sib tham nrog tus kws kho mob tsis pom zoo kom "Prosulpin" phau ntawv qhia. Nws analogues kuj muaj lawv ib tug neeg sab zoo. Lawv muaj peev xwm coj zoo raug mob rau tus neeg mob lub cev.

Cov lus teb ntawm kev kho mob txhais tau tias "Prosulpin"

Xyuas ntawm lub saum toj no cov tshuaj feem ntau zoo. Ib tug ntau ntawm cov neeg mob uas noj nws nyob rau hauv depressive lub xeev. Lawv hais tias qhov no cuab tam yuav pab tshem tawm cov tsos mob ntawm tus kab mob no yog yuav luag 100%.

Tsis tas li ntawd, muaj ntau yam cov neeg mob txaus cov lus teb, uas nyob rau hauv cov kab mob xws li schizophrenia, enterocolitis, mob plab, psychosis, enteritis, ulcerative kab mob, chim siab plob tsis so tswj syndrome, coj cov tshuaj "Prosulpin". Xyuas ntawm qhia tau tias nyob rau hauv tag nrho cov mob, lub cuab tam ua ib qho zoo kawg zoo nyhuv. Nyob rau hauv tas li ntawd, cov neeg mob qhia tias muaj kev phiv tshwm sim heev tsis tshua muaj.

Qhov saum toj no tshuaj muaj kev phiv loj heev, li ntawd, siv nws tsis muaj ua ntej kev sib tham nrog tus kws kho mob txwv tsis pub.