Cov lus qhia rau kev siv "tiapridal". Analogs thiab xyuas

"Tiapridal" - antipsychotic tshuaj manufactured los ntawm tiapride. Cov tshuaj yog thov raws li ib tug sedative, analgesic thiab hypnotic. Hauv paus ntawm antipsychotic txiav txim - thaiv cov hlab qhov dopamine receptors, uas ho cuam tshuam rau hauj lwm ntawm lub Cns. Nyob rau hauv no tsab xov xwm peb piav qhia txog nyob rau hauv kom meej txog cov tshuaj.

Muaj pes tsawg leeg muaj cov tshuaj

Cov tshuaj no muaj nyob rau ob cov ntaub ntawv, cov ntsiav tshuaj yuav tau muas thiab cov tshuaj:

• Ib tug ntsiav tshuaj raws li ib tug ampoule comprises 100 milligrams ntawm lub ntsiab tivthaiv thiab koom haum pab tshuaj. Raws li koom haum pab khoom xyaw uas siv nyob rau hauv nyob tus yeees ntawm povidone, magnesium stearate, mannitol. Muaj pes tsawg leeg yog tseem supplemented nrog ib tug aqueous colloidal dioxide, silicon thiab microcrystalline cellulose.
• Sib nrug los ntawm lub ntsiab tivthaiv ntawm cov tshuaj muaj sodium tshuaj dawb thiab dej rau txhaj tshuaj.

Nyob rau hauv ib lub thawv uas muaj 20 ntsiav tshuaj (2 hlwv nrog 10 ntsiav tshuaj) los yog 12 vials (2 hlwv ntawm 6 vials). Cov lus qhia rau kev siv "Tiapridal" nyob rau hauv daim ntawv ntawm ib tug tov rau txhaj pub muab intravenously thiab intramuscularly. Qhov no daim ntawv ntawm cov tshuaj no tsuas yog tsim rau cov kev kho mob rau cov neeg laus cov neeg mob.

Pharmacodynamics "tiapridal"

Lub medicament muaj neuroleptic, analgesic thiab anxiolytic kev txiav txim. Raws li cov phau ntawv qhia, "Tiapridal" xyua blocks hauj lwm ntawm D ₂ receptors ntawm central dopamine. Yog li nyob rau hauv D ₁ receptors muaj tsis ntxim. Cov tshuaj twg thiaj li raug tshem ntawm psoriasis, thaum uas siv nyob rau hauv cov neeg laus pab txoj kev xav.

Tshuaj "tiapridal"

Intramuscular thawj coj ntawm cov tshuaj (200 mg) ntawm nws cov qib siab tshaj plaws nyob rau hauv lub cev yog kuaj tom qab 30 feeb, siv lub ntsiav tshuaj nyob rau tib lub koob tshuaj - 60 feeb. Lub bioavailability ntawm cov tshuaj thaum uas siv tam sim ntawd ua ntej noj mov nrog 75% nce 95%. Vim hais tias cov tshuaj xws siv nce thiab nws cov qib siab tshaj plaws nyob rau hauv ib tug kab tsiaj txhuv (40%).

Haum nyob rau hauv lub cev yog qeeb qeeb nyob rau hauv cov neeg laus cov neeg mob. "Tiapridal" cov lus qhia rau kev siv hais txog ib tug neeg sawv cev crosses lub placental thiab cov ntshav-hlwb teeb meem. Nws yog lub npe hu hais tias thaum lub sij hawm kev kho mob cov tshuaj yog tam sim no nyob rau hauv nyob tus yeees ntawm cov kua mis. Nyob rau hauv cov poj niam, ib nrab kev tshem tawm ntawm cov tshuaj sai dua hais tias ntawm cov txiv neej (tshaj 2.9 teev), qhov txawv yog 0.7 sij hawm. Metabolism hauv yus li hauj sim. Lub ntsiab yog ib feem ntawm cov tshuaj (70%) yog muab tshem tawm los ntawm lub cev los ntawm ob lub raum unchanged.

Indications "Tiapridal" npaj

Yuav kom siv txoj kev kho nrog tshuaj "Tiapridal" nyeem ntawv raws li nram no:

• dyskinesia (tardive, tshwm sim);
• Gilles de la Tourette syndrome;
• chorea;
• tus cwj pwm mob (txhoj puab heev xeev, ntxhov siab thiab al.), uas ua nyob rau hauv ib tug ntau yam pauv loj txaus mob alcoholism thiab cov neeg laus cov neeg mob;
• tsis zoo ces nyob rau hauv tus cwj pwm, xws li txhoj puab heev xeev thiab ntxhov siab;
• mob intensive cim (mob daim ntawv no).

Contraindications, cov kev txwv tau txais "Tiapridal" tshuaj

Txwv tsis pub imposition ntawm "Tiapridal" cov lus qhia rau kev siv rau cov me nyuam uas nws muaj hnub nyoog yog tsawg tshaj li rau lub xyoo. Nyob rau hauv xyuas txoj kev kho yog nqa tawm tsuas tshuaj. Cov tshuaj yuav tsum tsis txhob yuav kho cev xeeb tub cov poj niam thiab cov neeg mob uas pub niam mis. Tshuaj yog tsis siv nyob rau hauv cov ntaub ntawv ntawm npau taws me ntsis rau nws lub Cheebtsam, thiab lwm yam xws li txhais tau tias. Contraindications xws li tej lub xeev:

• hepatic thiab lub raum tsis ua hauj lwm, uas muaj ntau heev heev;
• prolaktinzavisimogo diagnosing hlav, lub sijhawm twg los ntawm nws xub ntiag;
• hypertensive ntsoog;
• mob ntawm pheochromocytoma, ib tug suspicion ntawm nws lub neej.

Ntsiav tshuaj thiab cov tshuaj no yog siv ua ke nrog "sultopride" thiab dopamine receptor agonists (tsuas yog yog cov kev kho mob ntawm cov neeg mob nrog Parkinson tus kab mob) yuav tsis ua ke nrog tej hom neuroleptics, anti-arrhythmic cov neeg ua hauj teej tug mus rau cov chav kawm ntawv kuv thiab III A.

Medicating "Tiapridal" qhia tsis pub ib txhij siv "Moxifloxacin", "sparfloxacin", "Difemanila", "Erythromycin", "bepridil," "mizolastine", "levodopa", "cisapride" thiab nrog tso dej "vincamine" .

Yog hais tias tus neeg mob (tshwj xeeb tshaj yog cov neeg laus) raug kho nrog cov tshuaj uas tej zaum yuav ua rau txoj kev loj hlob ntawm hypokalemia, mob conduction deterioration, lengthening QT luv, qhov tshwm sim ntawm bradycardia qhia tus cwj pwm, siv lub "Tiapridal" yuav tsum tau ua tib zoo. Ceev faj yog yuav tsum tau nyob rau hauv xws li mob:

• Parkinson tus kab mob;
• congenital QT luv elongation cim;
• hypokalemia;
• mob raum tsis ua hauj lwm;
• bradycardia;
• cov kab mob nyob rau hauv uas cuam tshuam cov hlab plawv system (decompensation kauj ruam);
• qaug dab peg.

Kev kho mob nrog "Tiapridal"

nyob rau hauv daim ntawv thov ntawm "Tiapridal" phau ntawv xav siv ib tug thawj nyob rau hauv me me koob tshuaj, maj mam ua lawv, nyob rau hauv thiaj li yuav tau lub siab tshaj plaws cov nyhuv.

tus cwj pwm mob

Rau lawv nyem yog tsim nyog los thov 200 mg ntawm cov tshuaj txhua txhua hnub (mus txog rau 300). Qhov zoo nyhuv yog tiav nyob rau hauv rau lub lim tiam nyob rau nruab nrab. Laus cov neeg mob muab ib tug tsawg dua koob tshuaj - 50 mg. Ib tug tib koob tshuaj yuav tsum tau noj ib hnub ob zaug, thiab nws nce yog tso cai nyob rau hauv kev ua raws cai nrog rau cov qee luv, qhov kev txiav txim yog ua maj, noj mus rau hauv tus account tswv yim pab. Lub hnub koob tshuaj yuav tsum tsis txhob ntau tshaj 300 mg.

Mob mob mob heev

Lub hnub koob tshuaj ntawm cov tshuaj rau kev kho mob ntawm xws tej yam kev mob yog los ntawm 200 mus rau 400 mg.

Chorea, Gilles de la Tourette syndrome

Thaum nqa tawm kev kho mob ntawm tus me nyuam txhua txhua hnub koob tshuaj yog xaiv kev noj mus rau hauv tus account lub cev hnyav thiab hais txog 3-6 mg / kg. Yog hais tias koj xav tau los xyaum ua ib tug neeg laus txoj kev kho, thawj siv 25 mg ntawm cov tshuaj ib hnub twg, tom qab ntawd (tom qab ib tug gradual nce nyob rau hauv koob tshuaj) - 300-800 mg.

Ntxhov siab, aggression

Cov pom zoo txhua hnub koob tshuaj medicament yog los ntawm 100 mus 150 mg.

tus cwj pwm mob

Cov pom zoo koob tshuaj rau nruab hnub siv (los ntawm 200 mus rau 300 mg) nyob rau hauv cov ntaub ntawv ntawm delirious lub xeev los yog predelirioznogo nce mus rau 400-1200 mg. Qhov siab tshaj plaws tau koob tshuaj uas yuav tsum tsis txhob yuav zoo tshaj, yog 1800 mg. Cov kev taw qhia ntawm cov tshuaj ua nyob rau nruab nrab txhua tsib teev. Yog hais tias kev kho mob yog tsim nyog rau cov neeg laus neeg, txhua txhua hnub yog 2-3 tshuaj ntawm uas cai luv ntawm 6 teev. Rau cov kev kho mob ntawm xws cov neeg mob pom zoo txhua hnub kom tsawg ntawm 200 mus rau 300 mg ntawm medicament ntawm ib lub sij hawm yog tau tso cai rau nkag mus rau tsawg tshaj li 100 mg "tiapridal".

Khaus qhia ntawm ib tug mob xwm ntawm kev mob

Kev kho mob raws li cov xeem txhua txhua hnub koob tshuaj coj mus rau 200-400 mg ntawm cov tshuaj.

Sab los thaum noj "Tiapridal" tshuaj

Thaum kho cov tshuaj "Tiapridal" phau ntawv qhia, xyuas paub meej tias cov ntxim yuav zoo siv ntawm tej yam kev phiv tshuaj. Kev ua txhaum tej zaum yuav tshwm sim nyob rau hauv lub urogenital, lub paj hlwb, endocrine thiab kab systems. Nyob rau hauv tas li ntawd, muaj ib tug uas yuav muaj teeb meem nrog cov tsis totaub. Rau lwm tsis zoo los muaj xws li ua xua, daim tawv nqaij ces nrog koj qhov hnyav nce, orthostatic hypotension.

Overdose "tiapridal"

Yog hais tias koj siv ntev li koob tau overdose thiab nws cov tsos mob muaj xws li teeb nco qab, lub feem ntau loj heev ntawm uas - coma, neuroleptic syndrome (phem, mob forms). Nyob rau hauv thiaj li yuav kho lub xeev no ntawm tus kab mob yog nqa tawm kev kho mob raws li anticholinergic agents. Tom qab lub abolition ntawm cov tshuaj tsim nyog los nqa tawm symptomatic kev kho mob thiab plasmapheresis.

ceev faj

Ua ntej siv tshuaj "Tiapridal" phau ntawv qhia xav kom koj kho hypokalemia. Thaum lub sij hawm txoj kev kho nws yog ib qho tseem ceeb rau lossi saib xyuas ntsha tshuav nyiaj li cas, kev ib electrocardiogram, saib xyuas cov soj ntsuam daim duab hloov.

Yog hais tias nws yog tsim nyog los thov anticholinergic tshuaj ua tau txais neuroleptics extrapyramidal syndrome tsim es tsis txhob ntawm dopamine receptor agonist.

Thaum lub sij hawm ntawm kev kho mob yuav tsum tso tseg tej yam uas ua rau ib tug tej zaum kev hem thawj, nws yog tsis pom zoo kom ua hauj lwm uas yuav tsum tau kev pab tshwj xeeb thiab ceev cov lus teb.

Sis nrog rau lwm cov tshuaj

Ib txhia lawv tseem npaj nrog noj tshuaj "Tiapridal" kev qhia ntawv, cov tswv yim txuam nrog qhov tshwm sim ntawm tshwm sim ntawm undesired tshua. Nws tsis pom zoo thaum lub sij hawm kev kho mob muaj ntaub ntawv "Clonidine", antihistamines, anxiolytics, barbiturates thiab opioids, raws li "tiapridal" nyhuv yuav muaj ntau pronounced. Vim incompatibility yuav tsum tsis txhob coj "levodopa" thiab dej caw. Tshuaj yuav muab tag nrho nrog rau kev siv neurotrophic tshuaj, analgesics, antidepressants, neuroleptics. High kev pheej hmoo ntawm orthostatic hypotension, muaj lub simultaneous siv antihypertensive tshuaj nrog "Tiapridalom".

Tus nqi ntawm cov tshuaj analogues, xyuas txog cov tshuaj "Tiapridal"

Yog hais tias tsim nyog kho mob "Tiapridal" txhais tau tias kev qhia ntawv piav qhia qhia rau koj paub li ib tug yeeb tshuaj yog. Tus nqi ntawm cov tshuaj yog ib yam uas tseem ceeb heev nyob rau hauv cov kev xaiv ntawm ib tug medicament rau kev kho mob. Cov tshuaj nyob rau hauv lub vials yuav yuav rau txog 995 rubles, thiab cov ntsiav tshuaj - rau 1,400 rubles.

Ntawm cov analogues ntawm cov tshuaj - "Eglonil", "Betamax". Ntawm hloov tej zaum yuav xaiv "Sulpiride" los yog "Prosulpin". Yog lwm analogue ntawm cov tshuaj - "tiaprid", nws yog suav tias yog lub feem ntau mus siv cuag, nws yog ib tug heev nrov xaiv, lub domestic tshuaj ntau lawm uas tseem ua hauj lwm nrog lub tuam txhab "Organic". Raws li ib feem ntawm "tiaprid" tuaj rau tib active tshuaj, uas yog ib feem ntawm cov tshuaj "Tiapridal". Pab analogs Guide qhia rau xaiv, thaum tus thawj yuav siv tsis tau ib txhij nrog ib co tshuaj ua mob tshwm sim thiab tsis muaj ib yam nyhuv. Mus rau yeeb tshuaj yog zoo tshaj plaws, coj mus rau hauv tus account ntau ntawm cov ntsiab lus xaiv.

Thaum lub sij hawm kev kho mob, nws yog ib qho tseem ceeb ua raws li tag nrho cov kws kho mob lub tswv yim thiab cov tswv yim, uas muaj cov lus qhia rau kev siv. "Tiapridal", raws li qhia los ntawm lub tswv yim, nyob rau hauv Feem ntau, yog siv los mus tshem tawm cov tej yam kev mob nrog tshee excitement thiab txhoj puab heev cwj pwm, dej psychosis. Feem ntau, cov neeg mob thiab cov kws kho mob yog txaus siab nrog lub txiaj ntsim ntawm txoj kev kho. Yeej, ib tug rov Hoob no yog tsis yuav tsum tau rau cov yog vim li cas hais tias cov nyhuv yog tsim tom qab qhov kev siv ntawm cov thawj cov hoob kawm. Xyuas qhia tias rau cov neeg mob tshuaj "Tiapridal" ib qho yooj yim mus use.