Noj qab haus huv, Npaj
Xav paub cov lus qhia rau kev siv "procainamide"
Nyob rau hauv peb lub teb chaws, tus tuag tus nqi los ntawm cov hlab plawv tus kab mob no yog ib tug ntawm cov uas qhov chaw ntawm lub lwm yam ua. Cuam tshuam cov neeg tsis saib tsis xyuas lawv cov kev kho mob, cov neeg pluag noj cov zaub mov, quav cawv thiab haus luam yeeb, ib tug sedentary txoj kev ua neej. Tam sim no muaj nyob rau ib tug loj tus naj npawb ntawm cov tshuaj uas tsis tsuas pab tau kom tiv nrog kab mob plawv, tab sis kuj yuav tiv thaiv lawv tshwm sim. Ib tug xws li tshuaj yog "novokainamid", cov lus qhia rau kev siv yuav tsum tau tham hereinafter.
cov tshuaj
Manufacturers tsim "procainamide" nyob rau hauv ob hom: cov ntsiav tshuaj thiab txhaj tshuaj.
Lub active tivthaiv ntawm txhua pwm yog procainamide, uas yog muaj nyob rau hauv cov ntsiav tshuaj ntawm 250 mg txhua, thiab ib tug tov ntawm 100 mg. Raws li koom haum pab tshuaj yog muaj nyob rau hauv lub ntsiav tshuaj: calcium stearate, starch thiab lactose.
Yog hais tias peb coj tus yeeb tshuaj tov, ntxiv Cheebtsam yog dej rau txhaj thiab sodium disulfide.
Pharmacodynamics "procainamide"
Yog hais tias peb tham txog ib tug kho "procainamide" Instruction txhais tes muaj raws li nram no: yog hais txog mus rau lub anti-arrhythmic tshuaj. Procainamide, uas yog ib feem ntawm lub ntsiab tshuaj raws li lub active ingredient muaj zoo membrane stabilizing nyhuv.
Nws mechanism ntawm qhov kev txiav txim yog ua raws li braking cov khoom ndlwg ntawm sodium ions thiab txo depolarization nqi pes tsawg theem. "Procainamide" quab yuam conductivity, thiaj li muaj cov excitability ntawm lub plawv mob nyob rau hauv lub ventricles thiab atria.
Procainamide yog muaj peev xwm muab thiab vagolytic vasodilating nyhuv, uas ua rau yus txo cov ntshav siab thiab tshwm sim ntawm tachycardia.
Thaum nws qhia tau hais tias ib daim ntawv thov ntawm cov tshuaj
Lub plawv tshuaj no yeej loj heev tshuaj, uas nyob rau hauv txhua rooj plaub yuav tsis tau muab tsis muaj ib tug kws kho mob tshuaj. Tsuas yog ib tug kws, muab lub mob thiab cov yam ntxwv ntawm tus neeg mob tej zaum yuav kom qhov tseeb kev khwv. Indications Siv "procainamide" raws li nram no:
- Cov neeg mob muaj kev txhawj xeeb tachycardia.
- Muaj yog ib tug ventricular ntxov ntxov ntaus.
- Atrial Flutter.
- Ventricular arrhythmia.
- Atrial ntxov ntxov ntaus.
- WPW syndrome.
- Atrial fibrillation.
- Lub plawv atherosclerosis teeb.
Tag nrho cov mob yog tsim tsuas yog tom qab ib tug meej kev soj ntsuam ntawm tus neeg mob.
Contraindications
nyob rau hauv daim ntawv thov ntawm "procainamide" Guide kuj muaj cov lus qhia rau contraindications rau kev siv ntawm cov tshuaj. Tau txais cov tshuaj no yog tsis qhia rau:
- Arrhythmia, uas yog tshwm sim los ntawm ib tug overdose ntawm mob glycosides.
- AV blockade 2 thiab 3 degrees.
- Yog hais tias muaj yog leukopenia.
- Npau taws me ntsis mus rau yeeb tshuaj.
- Yog hais tias muaj yog irregularities nyob rau hauv lub siab los yog lub raum.
- Nyob rau hauv lub xub ntiag ntawm myasthenia Heavy kev.
- Heart attack myocardial infarction kuj yog ib tug contraindication rau kev siv ntawm cov tshuaj.
- Kom cov ntshav siab.
- Atherosclerosis.
- Bronchial hawb pob.
- Cov lus qhia rau kev siv "procainamide" ceeb toom ceev faj lub sij hawm ntawm cov tshuaj rau cov neeg laus.
- Cardiogenic poob siab.
- Mauj lupus erythematosus, xws li tus kab mob no yav dhau los.
- Thaum lub sij hawm lub sij hawm ntawm kev pub niam mis.
- Nws yog undesirable rau siv nyob rau hauv cov me nyuam nyob rau hauv 18 lub xyoos laus "procainamide" phau ntawv qhia tsis muaj cov lus qhia txog cov hauj lwm zoo thiab kev ruaj ntseg ntawm cov tshuaj nyob rau hauv lub hnub nyoog no.
Ntau npaum thiab kev kho mob regimen
Cov tshuaj yuav tsum noj lus nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, tshuaj intravenously los yog intramuscularly.
Yog hais tias muab rau ib tug "novokainamid" tshuaj, cov lus qhia rau kev siv nyob rau hauv ampoules muaj ncauj lus kom ntxaws qhia txog ntawm cov ntawv thov kev pab.
Tso dej raws leeg thawj coj ntawm 100-500 mg procainamide yaj nyob rau hauv saline thiab muab maj mam, ntawm ib tus nqi tsis muaj ntau tshaj li 50 mg rau ib feeb. Thaum lub sij hawm zoo tas yuav mus tswj cov ntshav siab.
Muaj tej yam teeb meem uas yuav tsum rov thawj coj ntawm lub tib lub npaum li cas ntawm cov tshuaj mus cuag lub Desired nyhuv. Nyob rau hauv kev txiav txim arrhythmia tiv thaiv Txoj kev lis ntshav yog nqa tawm ntawm ib tus nqi ntawm 2-6 mg ib feeb.
Thaum docked nres, yuav muaj cov nyhuv ntawm intramuscular txhaj ntawm ib tug yeeb tshuaj nyob rau hauv ib tug npaum li ntawm 0.5-1 grams.
Raws li ib tug kho tus neeg saib xyuas "novokainamid" muab intramuscularly nyob 50 mg rau ib kg ib tus neeg mob ib hnub twg, cov tshuaj yuav tsum tau muab faib ua ob peb tshuaj.
Qhov siab tshaj plaws tshuaj rau cov neeg laus los tso dej los yog intramuscular thawj coj yog 1 gram ib txhaj tshuaj, los yog 3 grams tauj ib hnub.
Txhais tau hais tias rau "procainamide" cov lus qhia rau kev siv tshuaj thaum pib ntawm kev kho mob yog pom zoo kom noj ib teev ua ntej noj mov los yog 2 teev tom qab noj mov. Zom cov ntsiav tshuaj yog tsis tsim nyog, thiab haus dej haus kom txaus dej.
Yog hais tias muaj yog tsis muaj kev phiv, ces koj yuav pib tau txais cov kev kho koob tshuaj, nws yuav tsum yog los ntawm ib mus rau peb cov ntsiav tshuaj. Rau txij nkawm kev kho mob cov kws kho mob prescribes ib ntsiav tshuaj txhua txhua 6 teev.
undesirable los
Yog hais tias prescribers "procainamide" cov lus qhia rau kev siv yuav tsum tau zoo to taub. Nyob rau hauv nws koj yuav nrhiav tau cov lus qhia txog qhov tshwm sim ntawm cov kev phiv thaum lub sij hawm kev kho mob nrog cov tshuaj no. Cov muaj xws li:
- Ataxia.
- Psychotic tshua.
- Cov tsos mob chua leeg hlwb.
- Kiv taub hau.
- Nyob rau hauv loj heev zaum, nws los mus rau hallucinations.
- Myasthenia Heavy kev.
- Muaj heev mob taub hau.
- Tus neeg mob yuav pib txom nyem los ntawm kev nyuaj siab.
- Muaj tej lub sij hawm ntawm kev tsim txom ntawm medullary hematopoiesis.
- Disturbed saj.
- Mob anemia.
- Muaj ventricular tachycardia.
- Arterial ntshav siab yog txo.
- Cuam tshuam intracardiac conductivity.
Yog hais tias "procainamide" txoj kev kho yog kho rau ib ntev lub sij hawm, nws muaj peev xwm tsim lupus. Ib txhia neeg kuj tau qhia hais tias thaum lub sij hawm kev kho mob nrog microbial kab mob muaj peev xwm tua, thiab muaj yog ib tug ntev lub sij hawm ntawm kev kho neeg mob.
Symptomatology tshuaj overdose
Cov ntawv twb yog ib tug kho "procainamide" qhia piav qhia, tus duab hauv qab no qhia tau hais tias, uas tej zaum yuav tsos mob ntawm overdose thaum lub sij hawm kev kho mob.
Nws yuav tsiag ntawv los ntawm cov nram qab no cov tsos mob:
- Loj kiv taub hau.
- Somnolence.
- Tej zaum tsaus muag.
- Tsis meej pem.
- Ntuav.
- Quickens lub plawv dhia.
- Muaj yog ib tug paroxysmal tachycardia.
- Tus neeg mob loses qab los noj mov.
- Zawv plab pib.
- Txo cov ntshav siab.
- Cev qhuav dej.
Rau thawj pab yuav tsum tau muab rau tus neeg mob, "Phenylephrine" thiab "norepinephrine" yog hais tias cov ntshav siab poob. Txhais tau tias zoo ntawm kev pab yog pais plab lavage, hemodialysis.
Drug sis raug zoo nrog lwm yam tshuaj
nyob rau hauv daim ntawv thov ntawm "procainamide" phau ntawv muaj cov lus qhia rau kev siv yeeb tshuaj cov kev sib tshuam nrog lwm yam tshuaj. Koj yuav tsum paub ua ntej koj pib txoj kev kho nrog hais tias:
- Cov tshuaj yuav pab cov nyhuv ntawm kev noj hnaiv, anticholinergics.
- Amplifies tej yam uas antihypertensive tshuaj.
- Yog hais tias coj nyob rau tib lub sij hawm, antihistamines, atropine yog kho kom zoo.
- Yog hais tias tus txais tos yog nqa tawm nyob rau tib lub sij hawm "Pimozoda" uas yuav pom nyob rau ib qho electrocardiogram lengthening ntawm lub luv QT.
- Cov tshuaj tsub kom lub sab los thaum noj "bretylium tosylate."
- Nws tsub kom qhov yuav tsim arrhythmogenic nyhuv yog ob qho tib si tsa los ntawm antiarrhythmic tshuaj.
- Tau txais ib leeg "Cimetidine" tsub kom lub ib nrab-lub neej "procainamide" thiab thiaj li muaj lub raum clearance.
Ua ntej lub sij hawm teem ntawm cov tshuaj tus kws kho mob yuav tsum nug dab tsi tshuaj tus neeg mob yuav siv sij hawm, coj mus rau hauv tus account tag nrho cov tau kev sib tshuam.
Tseem ceeb sau ntawv thaum tau txais "procainamide"
Nws tau hais tias koj yuav tsum noj cov ntsiav tshuaj ntawm cov tshuaj nyob rau hauv ib qho kev npliag plab los yog tom qab ib tug ob peb teev tom qab noj mov. Ntxuav cia nrog ib tug yuav pab tau cov mis los yog dej. Yog hais tias tsa txhaj tshuaj, cov tshuaj yuav tsum tau diluted ua ntej thawj coj.
Thaum lub sij hawm kev kho mob "procainamide" yuav tsum lossi saib xyuas ntshav siab, ntshav leukocytes thiab ua ib qho electrocardiogram.
Tom qab kev kho mob ntau tus neeg mob kaw kom ntau ntau cov antinuclear antibody titer. Yog hais tias ntev-lub sij hawm kev siv ntawm cov tshuaj tom qab phais rau hauv lub plawv, ces tej zaum yuav tsim leukopenia.
Cov laus cov neeg mob uas muaj feem yuav rau hypotension, li ntawd, koj xav tau kom lub siab nyob rau hauv kev tswj. Kev ceev faj yuav tsum tau siv thaum muab cov tshuaj no rau cov me nyuam. Ntau npaum yuav tsum tau ua tib zoo xam.
Txais tos "procainamide" muaj feem xyuam rau koj concentration, yog li ntawd koj yuav tsum caiv txhob tsav tsheb thaum lub sij hawm txoj kev kho nrog cov tshuaj no. Tsis tas li ntawd ua tib zoo saib thiab cov kev ua ub uas yuav tsum nce mloog thiab concentration, thiaj li tsis tau raug mob.
Noj cov tshuaj thaum lub sij hawm cev xeeb tub
nyob rau hauv daim ntawv thov ntawm "procainamide" phau ntawv ceeb toom hais tias cov kev siv ntawm cov tshuaj thaum lub sij hawm cev xeeb tub yuav ua rau ib tug txo nyob rau hauv cov ntshav siab, uas, nyob rau hauv lem, feem ntau ua rau cov utero-placental insufficiency.
Drug analogues thiab txhais
Analogues ntawm tej tshuaj yog cov tshuaj uas muaj ib tug zoo feem nyob rau hauv lub cev. Yog hais tias peb xav txog cov tshuaj "procainamide" (piav qhia, analog yees duab), ces nws muaj ib tug ob peb ntawm cov tshuaj:
- "Ajmaline" raws li ib tug concentrate rau tov.
- "Aymalin" nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj.
- "Quinidine Sulfate".
- "Hinipek" tshuaj.
Txawm tias muaj tseeb hais tias tag nrho cov analogues muaj ib tug zoo ua hauj lwm, tom qab tag nrho, nws yog tsis tsim nyog los muab lawv tus kheej cov tshuaj nws tus kheej. Tus kws kho mob noj mus rau hauv tus account nta ntawm tus kab mob, thiab kuj assigns tus neeg mob ib tug yeeb tshuaj uas yuav ua tau zoo dua.
Nyob rau hauv tas li ntawd mus cim, muaj cov tseem synonymous nyob rau hauv "procainamide", yog tshuaj nrog tib yam kom nquag plias khoom sib ua zaub mov. Rau cov neeg muaj xws li:
- "Novokainamid-Verein" - yog ib tug tov rau tso dej thiab intramuscular txhaj tshuaj.
- "Procainamide-Escom" kuj yog ib tug tshuaj rau kev txhaj tshuaj.
Nrog tej yam kab mob koj yuav yeej ib txwm xaiv lub analogues thiab txhais ntawm kev yeeb tshuaj, uas yog tus kws kho los ntawm ib tug kws kho mob. Muaj ntau cov neeg mob yuav ua los ntawm cov nqi thiab sim mus yuav cheaper counterparts, tab sis nws yuav tsum tau nco ntsoov tias active ingredient tej zaum yuav tib yam, tab sis ua ke nrog lwm yam ua ke nrog yuav muab ib tug txawv kiag li cov nyhuv. Prisushivaytes lub tswv yim ntawm cov kws txawj, thiab tsis self-medicate, ntxiv tsis ua phem rau koj noj qab haus huv.
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