Drug 'Atenolol Nycomed'

Rau tshuaj "Atenolol Nycomed" muaj tshuaj, thiab thoob ntiaj teb tsiaj ntawv nrog lub npe ntawm "Atenolol". Nyob rau hauv cov lus ntawm chemists pharmacologists structurally tshuaj tshwm li (REYE) -4- (2-hydroxy -3- (isopropylamino) phenyl-acetamide. Ntsiav tshuaj "Atenolol" sawv cev oboevypuklye coated tshuaj dawb xim, muaj ib tug capsule zoo. Lub cev lub ntsiab yog muab thais rau ib tug so nyob rau hauv ib tes, muaj tej yam tshwm sim AV55 thiab AV57.

Nyob rau hauv ib ntsiav tshuaj, nyob ntawm seb qhov kev tso tawm daim ntawv tej zaum yuav muaj tsib caug los yog ib puas milligrams ntawm atenolol. Raws li koom haum pab Cheebtsam siv talc, gelatin, propylene glycol, titanium dioxide, magnesium stearate, ipromeloza 2910 (15sP), pob kws starch, sodium lauryl sulfate, hnyav magnesium carbonate.

Tshuaj "Atenolol Nycomed" ua raws li ib tug beta1-xim (cardioselective) adrenoceptor thaiv cov hlab neeg sawv cev, daim nyias nyias stabilizing kev ua si yog tsis. Qhov cuab yeej no qhia tau hais tias antianginal, antiarrhythmic thiab hypotensive nyhuv. Nws muaj peev xwm sawv ntawm thaiv cov hlab beta-adrenergic receptors ntawm lub plawv, txo myocardial stimulation ntawm lub sympathetic division nyob rau hauv lub autonomic lub paj hlwb thiab catecholamines, uas circulate nyob rau hauv cov ntshav. Tshuaj "Atenolol" nyhuv rau kom txhob muaj qhov ntswg automaticity, normalizes lub lub plawv dhia mus rau ib tug standstill thiab thaum lub sij hawm ib ce muaj zog. Qhov no stabilizes tus txheej txheem thiab excitation ntawm myocardial contractility, tseg ntxim rau cov AV-conduction. Nyob rau hauv nws daim ntawv thov yog ib tug txo nyob rau hauv myocardial oxygen thov. Favorably muaj feem xyuam rau lub systematic siv cov tshuaj "Atenolol" rau txos cov ntshav siab. Stabilization ntawm lub antihypertensive nyhuv tshwm sim los ntawm tus kawg ntawm lub lim tiam thib ob ntawm kev txais tos.

Kev npaj "Atenolol Nycomed" raws li qhov ncauj txais tos txoj kev muaj peev xwm absorbed nyob rau hauv cov hnyuv nyob rau hauv lub ntim ntawm 50-60% ntawm cov muab koob tshuaj. Tas nyob hauv cov zis nrog ib tug ib nrab-lub neej ntawm 6-7 teev. Cov sij hawm nyob rau hauv cov neeg mob uas raum tsis ua haujlwm zoo, nyob ntawm seb tus nqi ntawm glomerular filtration.

Indications rau cov tshuaj yog "Atenolol Nycomed" cov ntaub ntawv ntawm tawg thiab tachyarrhythmias (xws li qhov ntswg). Thov cov tshuaj thiab raws li ib tug tiv thaiv kev neeg sawv cev rau angina sib cem.

Lub sij hawm ntau npaum ntawm cov tshuaj rau cov neeg laus nyob rau hauv cov kev kho mob ntawm angina thiab tawg nce mus txog 50-100 mg. Nkag ntsiav tshuaj ua los rau ob lub sij hawm ib hnub twg nyob rau hauv view ntawm lub fact tias cov hnub koob tshuaj yuav tsum tsis txhob ntau tshaj 200 mg. Yuav kom ntxuav cia cov tshuaj yuav tsum tau ib tug me nyuam npaum li cas ntawm cov dej.

Cov tshuaj no yog siv nyob rau hauv nruj raws li cov tswv yim pom zoo ntawm cov kws kho mob. Self-tshuaj yog tsis tau tso cai. Cov tshuaj "Atenolol Nycomed" muaj kev phiv. Lub plawv system yuav teb cov tsos ntawm bradycardia, AV-conduction ua cuam tshuam, tej zaum koj yuav muaj kev ncus ntawm paresthesia thiab txias nqua, nyob rau hauv tej rooj plaub tshwm sim tsos mob ntawm lub plawv tsis ua hauj lwm. Hnyuv reacts tsis zoo mus rau yeeb tshuaj xeev siab, cem quav, raws plab, qhov ncauj qhuav (muaj tsawg heev), lub endocrine system - cov tau txoj kev loj hlob ntawm ib tug hypoglycemic mob nyob rau hauv cov neeg mob kev txom nyem los ntawm cov ntshav qab zib, urogenital system - tau txo nyob rau hauv potency. Cns phiv tshuaj tej zaum yuav tshwm sim nyob rau hauv mob taub hau, kiv taub hau, pw tsis taus, kev nyuaj siab, kev xav ntawm qaug zog. Nws tseem yog tau kev tsis haum tshuaj, khaus, thiab liab. Mob amplification perspiration, yuav txo tau ntawm tsim kua muag kua secretion raug kaw, tshwm sim ntawm conjunctivitis.

Tsis tas li ntawd, muaj ib tug xov tooj ntawm contraindications. Nyob rau hauv lawv daim ntawv teev muaj xws li tus neeg theem ntawm mob hauv lub plawv tsis ua hauj lwm, bradycardia, hypotension, nce rhiab heev mus rau yeeb tshuaj, thiab lwm tus neeg.

Khaws cov tshuaj nyob rau hauv ib tug qhuav qhov chaw, kev tiv thaiv los ntawm lub teeb, cov cais tawm ntawm cov me nyuam. Room kub rau 25 ° C. Ib tug yeeb tshuaj koom tes nws lub zog rau tsib lub xyoos.