Tshuaj "primidone": cov lus qhia rau kev siv thiab cov tswv yim

Niaj hnub nimno kws tuam txhab uas muag tsim ib tug loj tus naj npawb ntawm antiepileptic tshuaj. Yuav ua li cas to taub ntau yam ntawm cov tshuaj? Ua li no, tig mus rau tej tub txawg. Nws yuav tau mus xaiv rau koj qhov zoo tshaj tshuaj, uas yuav ua rau kom muaj teeb meem loj lub vaj txiaj ntsim ntawm tus neeg mob.

Cov feem nrov antiepileptic tshuaj cov neeg mob thiab cov kws kho mob yog cov tshuaj "primidone". Cov lus qhia rau kev siv ntawm hais tias cov tshuaj, qhov kev tso tawm daim ntawv thiab nws cov khoom yuav tsum tau nthuav tawm ib tug me ntsis rau yav tom ntej.

Muaj pes tsawg leeg, zoo lawm thiab ntim

Yuav cov tshuaj "primidone" yuav ua tau nyob rau hauv ob hom sib txawv. Nws yog muaj raws li ib tug hmoov uas yog fej nyob rau hauv ib tug dual-txheej hnab yas thiab cov duab los qhia lub thawv, ntsig txog. Nws kuj txhais tau tias koj yuav yuav nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nyob rau hauv sawv hlwv packs thiab cartons.

Lub active muaj nyob rau hauv cov tshuaj no ua primidone. Tsis tas li ntawd nws muaj koom haum pab (nyob ntawm seb qhov kev tso tawm ntaub ntawv).

Qhov kev txiav txim ntawm cov tshuaj

Yuav ua li cas yog tus kho rau "primidone"? Cov lus qhia rau kev siv qhia hais tias qhov no antiepileptic tshuaj. Nws muaj txhawb rau me me hypnotic nyhuv, tab sis kuj txo lub excitability ntawm lub neurons uas muaj nyob rau hauv lub epileptic kom pom tseeb.

Yuav ua li cas lwm yam khoom xam qhovkev nyob rau hauv lub medicament "primidone"? Qhov tseem ceeb co thaum nws eliminates ntshav concentration ntawm 12 .mu.g / ml.

kev tig tau zog

Tshuaj "primidone" (ntsiav tshuaj thiab hmoov) haum sai thiab yuav luag tag nrho absorbed los ntawm cov hnyuv ib ntsuj av. Qhov siab tshaj plaws concentration ntawm cov tshuaj tiav tom qab peb teev. Lub bioavailability ntawm cov tshuaj no yog 90-100%. Nyob rau hauv cov ntshav nws uake rau cov nqaijrog me ntsis (kwv yees li 20%).

Ib nrab-lub neej ntawm no neeg uas sawv cev 7-15 teev.

Nyob rau hauv lub siab, lub medicament yog cov hloov siab los ntseeg phenobarbital (txog 20%) thiab feniletilmalonamid. Cov metabolites muaj antiepileptic kev ua si. Lawv tas los ntawm ob lub raum.

Tus neeg mob cov ntshav yog tsim nyog kom muaj ib tug kho yeeb tshuaj concentration ntawm 12 ug / ml. Nws yog ib cov indicators ua rau kom tseg qaug dab peg. Thaum lwm cov ntaub ntawv ntawm qaug dabpeg (e.g., uas tsis yog-convulsive ntaub ntawv ntawm polymorphous qaug dab peg thiab lwm yam), cov nyhuv ntawm txoj kev kho yog tsis ib txwm tau tiav. Nyob rau hauv cov ntaub ntawv no, lub complex kev kho mob.

Indications rau kev siv ntawm cov tshuaj

Nyob rau hauv tej rooj plaub, tus neeg mob yog tshuaj xws li "primidone"? Xyuas tau qhia hais tias qhov no lub cuab tam zoo hlub qaug dab peg ntawm ntau yam keeb kwm, raws li tau zoo raws li ib nrab thiab generalized qaug dab peg. Nrog rau txoj kev loj hlob ntawm focal, myoclonic thiab akinetic qaug dab peg tshuaj no tsis tshua zoo.

Contraindications tshuaj

Nyob rau hauv tej rooj plaub, tsis txhob muab cov tshuaj "primidone"? Cov lus qhia rau kev siv ntawm cov lus ceeb toom hais tias nws yog txwv tsis pub siv txhais tau tias nyob rau hauv lub xub ntiag ntawm ib tug npau taws me ntsis (xws li barbiturates), raws li zoo raws li anemia, daim siab thiab lub raum tsis ua hauj lwm, cev xeeb tub, tawg thiab pub niam mis.

Tshuaj "primidone": cov lus qhia rau kev siv

Nyob rau hauv dab tsi ntau npaum yog tshuaj ib tug yeeb tshuaj peb xav? Nws yog coj lus tom qab noj mov noj nyob rau hauv ib tug ib zaug xwb-lub sij hawm txhaj koob tshuaj ntawm 125 mg. Tom qab hais tias, txhua txhua peb hnub, hais tias lub xov tooj ntawm cov tshuaj muaj zog los ntawm 250 mg rau cov neeg laus cov neeg mob thiab 125 mg rau cov me nyuam uas tau mus txog lub hnub nyoog ntawm 9.

Qhov no txoj kev kho yog txuas ntxiv txog thaum lub Desired tshwm sim.

Qhov siab tshaj plaws txhua txhua hnub koob tshuaj rau cov me nyuam yog 1 g (nyob rau hauv ob ua sawv) thiab cov laus - 1.5 g

phiv

Tu siab, ua ntej peb antiepileptic tshuaj feem ntau ua rau undesirable los. Cov no muaj xws ntev tsaug zog, mob taub hau, kiv taub hau, ntxhov siab vim, nkees, xeev siab, anemia, ntuav, leukopenia, allergic kev tig cev, thiab lymphocytosis.

Heev tsis tshua active medicament yuav ua nystagmus, ataxia, "lupus" syndrome, psychotic tshua, arthralgia, megaloblastic anemia, thiab lub caij nyoog siv - tshuaj dependence.

tus neeg mob ntawm overdose

Noj loj koob tshuaj ntawm cov tshuaj yuav ua rau cov tsos mob xws li kiv taub hau, ataxia, xeev siab, thiab kev nyuaj siab ntawm lub hauv paus poob siab system ua hauj lwm. Rau cov kev kho mob ntawm xws tej yam kev mob rau tus neeg mob yog ntxuav lub plab, tshuab txais hluav ncaig thiab symptomatic kev kho mob.

Compatibility nrog lwm yam tshuaj

Kev npaj "primidone" derivative potentiates cov nyhuv ntawm cyclophosphamide, methotrexate thiab sulfonylureas raws li hypnotics. Nws kuj accelerates metabolism, tsub kom cov kev ua ntawm microsomal siab enzymes, thiaj li muaj cov nyhuv ntawm corticosteroids, acetaminophen, ISS, tricyclic antidepressants, anticoagulants, "chloramphenicol", "DTIC", "Cyclosporin" mob glycosides "disopyramide", "Levothyroxine", "Doxycycline "" theophylline "," metronidazole "," Quinidine "," mexiletine "ntawm vitamin D,« fenoprofen, "caffeine" Aminophylline "thiab" oxtriphylline. "

Saib medicament tej Cns kev nyuaj siab nyob rau hauv ua ke nrog nrog txhais tau tias ib tug central depremiruyuschim kev txiav txim thiab haus dej cawv.

Tshuaj "amphetamine" slows qhov haum ntawm phenobarbital.

Nyob rau hauv ua ke nrog nrog carbonic anhydrase inhibitors amplified osteopenia.

Qhov no thiaj li haum ntawm griseofulvin neeg sawv cev uas thiaj li nws noj ua si. Nws kuj pab tau lom los "enflurane", "methoxyflurane" thiab "halothane".

"Methylphenidate" txhawb inhibition ntawm metabolism thiab primidone rau kom nws cov concentration hauv cov ntshav.

"Leucovorin" loj koob tshuaj thiaj li cov nyhuv ntawm anticonvulsant primidone. Tib yam siv rau cov tshuaj "phenylbutazone".

tej tswv yim pom zoo

Tshuaj "primidone" yuav siv tau nyob rau hauv txoj anticonvulsant kev kho mob. Tshem tawm thiab hloov ntawm cov tshuaj yog maj.

Nrog zoo saib xyuas, nws raug tsa cov neeg laus thiab immunocompromised neeg. Nrog rau txoj kev loj hlob ntawm megaloblastic anemia medicament rho thiab muab kev kho mob uas muaj vitamin B12 los yog folic acid.

Cov kev kawm neeg sawv cev thiaj li tib neeg psychomotor tshua. Yog li ntawd, nws tsis txhob muab tus tsav tsheb ntawm cov tsheb thiab cov neeg uas nws ua hauj lwm yog kev cob cog rua nrog yus machinery.

Nrog kev saib xyuas cov tshuaj no yog siv nyob rau hauv cov me nyuam.

zoo xws li cov txhais tau tias

Cov tshuaj yuav tau muab hloov los ntawm "primidone"? Analogues ntawm no lub cuab tam yuav yuav tau nyob tej chaw muag tshuaj los yog kev txiav txim los ntawm lub ntiaj teb dav Web.

Raws li cov kws tshwj xeeb, muaj zoo xws li cov zog xws tshuaj raws li "hexamidine", "Benzonal" thiab "Phenobarbital".

Testimonials

Tau txais kev pab uas tau antiepileptic tshuaj xws li "primidone" tawm nws tsuas zoo lub tswv yim. Raws li lawv qhia, cov tshuaj copes zoo nrog nws cov neeg ua hauj lwm. Nws tiv thaiv qhov tshwm sim ntawm ib nrab thiab generalized qaug dab peg. Tsis tas li ntawd, qhov no tshuaj pab txo cov tsos mob ntawm tus qaug dab peg.

Raws li rau qhov tsis zoo xyuas, yuav luag tag nrho cov ntawm lawv taw tes rau lub fact tias no lub cuab tam muaj txhawb rau rov tshwm sim ntawm ib tug loj tus naj npawb ntawm cov kev phiv. Yog li ntawd, mus thov xws li ib tug tshuaj yuav tsum tsuas yog rau tus kws kho mob lub sij hawm.