Streptomycin rau cov tsiaj: cov lus qhia rau kev siv, kev piav qhia thiab kev txheeb xyuas

Yuav ua li cas yog tus nqi li cas thiab yog muaj ib tug Veterinary tshuaj raws li "streptomycin"? Cov lus qhia rau kev siv, tus nqi, thiab lub sij hawm ntawm cov tshuaj yuav tsum tau muab los sib tham li hauv qab no.

Daim ntawv piav qhia ntawm veterinary chaw

Kev npaj "streptomycin Sulfate" (kho tsiaj) yog ib tug organic puag ntsev uas yog ua los ntawm radiant me pwm.

Cov muag khoom ntawm no txhais tau tias yog nkag raws li ib tug hygroscopic hmoov los yog ntxeem tau loj ntawm dawb xim, ab saj, tsis muaj tsw thiab yog yooj yim soluble nyob rau hauv dej, novocaine thiab saline.

"Streptomycin" rau kev kho tsiaj yog li ntawd feem ntau siv raws li xav tau. Nws yuav tsum tau muab sau tseg tias nws yog ruaj khov nyob rau hauv ib tug weakly acidic nruab nrab, tab sis zoo lawm nyob rau hauv alkaline daws teeb meem (nrog cua kub) thiab muaj zog acids.

pharmacology medicament

Yuav ua li cas puas cov tshuaj "streptomycin" rau cov tsiaj? Cov lus qhia rau kev siv ua dlejnum hais tias qhov no neeg sawv cev muaj bactericidal thiab bacteriostatic zog tiv thaiv ntau gram-tsis zoo thiab gram-zoo pathogenic cov kab mob.

Antimicrobial hauj lwm zoo ntawm cov tshuaj no yog txiav txim los ntawm nws muaj peev xwm inhibit protein synthesis nyob rau hauv microbial hlwb nyob rau hauv ribosome theem. Nws kuj sau tseg tias cov tshuaj muaj tsis ntxim rau ib tug kab mob tshwm sim los ntawm Clostridia thiab lwm yam co kab mob, fungi, plasmodia, cov kab mob thiab rickettsia. Tsis tas li ntawd, tej yam kab mob muaj zoo heev kuj mus streptomycin, thiab cov kab mob proliferating nyob rau hauv tsis kam mus rau tshuaj tua kab mob tshwm sim nyob rau hauv ib ob peb hnub. Feem ntau ntawm cov tshuaj-resistant hom tsim los ntawm tus kawg ntawm lub ob hlis ntawm kev kho mob. Yuav kom tiv thaiv no tshwm sim thiab mus rau tshem tawm tus kab mob no, koj yuav tsum tau siv loj koob tshuaj ntawm cov tshuaj, raws li zoo raws li mus ua ke nrog lwm cov antimicrobial agents.

Lub pharmacokinetic yam ntxwv ntawm cov tshuaj

seb cov tshuaj yog absorbed, "streptomycin" rau cov tsiaj? Cov lus qhia rau Siv hais tias thaum nkag tau rau hauv nws tsis yog absorbed thiab tag tshem tawm los ntawm cov quav.

Rau intramuscular tshuaj lub active ingredient ntawm cov tshuaj yog absorbed sai li sai tau mus rau hauv cov hlab ntsha, thiab yog tseem pom nyob rau hauv lub pleural thiab peritoneal kab noj hniav, cov kua tsib, vitreous lom zem, zis, thiab ob lub qhov muag.

Nyob rau hauv mob o nyob rau hauv lub pleural kab noj hniav ntawm tus concentration ntawm cov tshuaj tua kab mob tus neeg saib xyuas yuav ncav cuag hais txog 50% ntawm cov theem nyob rau hauv cov ntshav.

Nyob rau hauv tsim meningitis streptomycin tau txeem mus rau hauv cov leeg nrob kwj dej hauv tus nqi ntawm 10-50%.

Cov kev kawm neeg sawv cev yuav yooj yim kis los ntawm tej lub tsev me nyuam. Nyob rau hauv lag luam, streptomycin siab accumulates nyob rau hauv siab ntau nyob rau hauv lub hepatic tubules. Thaum ntxhov muaj nuj nqi ntawm no lub cev nws nkag mus rau hauv cov kua tsib nyob rau hauv me me qhov ntau, thiab cholecystitis nws cov ntsiab lus nyob rau hauv lub tsib zais zis yog hais txog 85% ntawm cov theem nyob rau hauv cov ntshav.

Therapeutic streptomycin concentration nyob rau hauv ntau yam ntaub so ntswg thiab kabmob khaws cia rau 8-13 teev. Qhov no cov ntaub ntawv uas zoo nkauj sai sai tas nyob hauv cov zis.

Indications rau tshuaj

Uas hlub cov kab mob ntawm cov nyiaj? Yuav ua li cas no hais tias cov lus qhia rau kev siv ntawm cov tshuaj? "Streptomycin sulfate" teev:

• nrog leptospirosis, tularemia, mob ntsws;
• edema kab mob ntawm npua thiab erysipelas, catarrhal ua npaws (phem);
• diplokokkovyh kab mob, mastitis, endometritis;
• endocarditis, meningitis, puerperal sepsis thiab mob;
• actinomycosis ntawm nyuj thiab campylobacteriosis, raws li zoo raws li lwm yam kab mob, kab mob uas yog rhiab heev rau streptomycin.

Bans siv

Thaum koj yuav tsum tsis txhob muab cov tshuaj "streptomycin" rau cov tsiaj? Cov lus qhia rau Siv nkag nrog cov tshuaj, hais tias cov nram qab no contraindications:

• siab tsiaj rhiab heev rau aminoglycoside tshuaj tua kab mob;
• muaj plawv thiab raum kab mob.

Nws yuav tsum tau muab sau tseg tias cov tshuaj tsis tau ua ke nrog rau lwm cov aminoglycoside tshuaj (xws li "neomycin" kanamycin "," monomitsin, "Gentamycin") vim hais tias ntawm cov tau nce lub nephrotoxic nyhuv.

Coj mus rau hauv kev npaj "streptomycin Sulfate" (nyob rau daim ntawv thov rau cov tsiaj)

Ua ntej siv, nws twb yaj nyob rau hauv xam tau tias yog txhais tau tias saline, muaj menyuam tsis taus dej, los yog 0.25-0.5% m novocaine tshuaj. Yog li ua raws li cov nram qab no kev sib raug zoo: 0.25 g streptomycin thiab 1 ml ntawm kuab. Los ntawm txoj kev, ib tug zib tov raws li ib lub xeem siv yog txwv tsis pub.

Ntau concentrated nyiaj tej zaum yuav mob heev heev. Lub tiav lawm tov yuav tsum muab cia rau hauv chav tsev kub rau ib lub lim tiam (dua li comprise ib tug txias chamber).

Yuav ua li cas kuv yuav tsum tau siv cov tshuaj "streptomycin" rau cov tsiaj? Cov lus qhia rau kev siv hais tias hauv lub tiav lawm tov yuav tsum muab intramuscularly thiab topically, topically, hais lus, vnutrivymyanno, intraperitoneal, intratracheal, intrauterine, thiab intracisternally.

Intramuscular tshuaj tsiaj yog sib sib zog nqus rau hauv cov nqaij. Tej kev kho yog nqa tawm rau 4-7 hnub. Lub medicament yog muab ib hnub ob zaug ntawm ib tug caij nyoog ntawm 12 teev tom qab noj tshuaj npaum cas:

• Nyuj zoo - 10 mg / kg ntawm cov laus cov tsiaj thiab 20 mg / kg ntawm cov tub ntxhais tsiaj;
• nees - 5 mg / kg ntawm cov laus cov tsiaj thiab 10 mg / kg ntawm cov tub ntxhais tsiaj;
• Nyuj loj - 5 mg / kg ntawm cov laus cov tsiaj thiab 10 mg / kg ntawm cov tub ntxhais tsiaj;
• dev, npua - 10 mg / kg ntawm cov laus cov tsiaj thiab 20 mg / kg ntawm cov tub ntxhais tsiaj;
• poj qaib - 30 mg / kg ntawm cov laus cov tsiaj thiab 40 mg / kg ntawm youngsters.

Nyob rau hauv leptospirosis tshuaj "streptomycin" muab rau 4-10 hnub nyob rau hauv ib tug ntau npaum ntawm 25 mg / kg. Nyob rau hauv ntau loj heev zaum, qhov no xov tooj tsub kom.

Nws yuav tsum tau muab sau tseg tias cov tshuaj no ua ke nrog "polymyxin B", "penicillin" thiab sulfanilamidnymi txhais tau tias yog tsim nyog. Qhov no ua ke nrog ntawm cov tshuaj yog ib synergistic txiav txim, raws li zoo raws li txwv tsis pub cov tsos ntawm pathogens resistant rau streptomycin.

phiv

Tam sim no koj paub tias dab tsi yog tsim nyog tshuaj "streptomycin sulfate." Cov lus qhia rau kev siv ntawm cov tsiaj tau raws li tau piav saum toj no.

Rau intramuscular tshuaj nyob rau hauv cov nyuj yuav manifested sai tsim kev tsis haum tshuaj, uas yog ib tug kev hem thawj rau lub noj qab haus huv thiab lub neej ntawm cov tsiaj. Cov tshwm sim ntawm tej teeb meem txuam nrog nta ntawm nws lub cev thiab tsis yog nyob ntawm seb ntau npaum ntawm lub tshuaj tua kab mob siv.

Tsis tas li ntawd, ntau yam teeb meem yuav tshwm sim tom qab cov thawj tswj hwm ntawm cov tshuaj, uas feem ntau yog tshwm sim los ntawm sensitizing ib tug tsiaj nrog rov kawm ntawm txoj kev kho.

Nyob rau hauv cov kev kho mob nrog cov tshuaj no nyob rau hauv cov tsiaj txhu yuav muaj cai tshuaj lom tshuaj, raws plab, tachycardia, dermatitis, lag ntseg thiab impaired lub cev muaj zog sib haum.

Nqi thiab xyuas

Tus nqi saib xyuas txhais tau tias (vial 1 g) yog hais txog 18 rubles.

Ib txhia kws txawj tsis pom zoo kom mus sib tov "streptomycin sulfate" thiab "penicillin" nyob rau hauv tib syringe. Txawm li cas los, lwm yam vets heev ntse siv no thaum lawv tseem nyob rau hauv cov kev kho mob ntawm cov tsiaj nyeg.

Cov neeg rau ib ntev lub sij hawm nyob rau hauv kev sib cuag nrog veterinary tshuaj, sib ceg hais tias xws li hu rau feem ntau ua rau lawv dermatitis txoj kev loj hlob.

Raws li cov kws txawj, lub slaughter ntawm cov tsiaj, uas "streptomycin" twb qhia, muaj cai los tuav tsuas yog ib lub lim tiam tom qab kawg thawj coj ntawm cov tshuaj. Cov nqaij ntawm cov tsiaj tua ua ntej lawv them, yuav tsum tau siv rau zus tau tej cov hmoov.

Raws li rau cov mis nyuj, nws yuav siv tau rau nws cov zaub mov hom phiaj kom txog rau thaum ob hnub tom qab kawg tshuaj thawj coj.