"Prepidil" (gel): piav qhia, cov lus qhia rau kev siv thiab cov tswv yim. Gel rau induction of labor

Vim li cas siv xws li ib tug yeeb tshuaj raws li "Prepidil" (gel)? Tswv yim rau cov hauj lwm zoo ntawm cov tshuaj, raws li zoo raws li indications ntawm no lub cuab tam yuav tau piav me ntsis qis. Peb kuj muab cov lus qhia yuav ua li cas mus thov cov hais tias cov tshuaj, ntau npaum li cas nws cov nqi thiab dab tsi yog nws kev khiav hauj lwm hauv paus ntsiab lus.

Hauj lwm, ntim thiab muaj pes tsawg leeg

Uas pob yog muaj tshuaj "Prepidil"? intracervical gel yog muag nyob rau hauv hnab yas pov tseg koob txhaj tshuaj nrog ib tug catheter. Lawv muab tso rau hauv lub hlwv thiab lub thawv ntawv, ntsig txog.

Translucent thiab khov tshuaj "Prepidil" (gel) muaj xws li ib active ingredient li dinoprostone. Raws li koom haum pab tshuaj ntxiv thereto colloidal anhydrous silica thiab triatsetilglitserol.

mechanism ntawm qhov kev txiav txim

Yuav ua li cas yog cov tshuaj "Prepidil"? Gel thaum lub sij hawm yog tau me nyuam nkoos ncauj tsev menyuam ripening. Nws active neeg sawv cev yog ib qho unsaturated fatty acid uas yog tsim nyob rau hauv physiological tej yam kev mob.

Cov tshuaj txiav txim hauv paus ntsiab lus nyob rau hauv nws cov intratservikalno siv tsis tau kawm. Txawm li cas los, cov kws txawj ntseeg tau hais tias dinoprostone kom nrov loj lub ncauj tsev menyuam cov ntshav khiav, li no accelerating nws maturation (softening, smoothing thiab qhib). Tej yam ua siab SIB nquag ntws generic kev hloov uas ua rau ib tug txo nyob rau hauv lub tsev me nyuam kuj thiab ua rau kom myometrial contraction, raws li zoo raws li tus me nyuam.

Peb kuj yuav tsum nco ntsoov hais tias ib tug siv tau lub caij ntawm cov nyiaj kuj yuav muaj ib tug stimulating nyhuv on cov nqaij ntshiv ntawm lub digestive ib ntsuj av. Nyob rau hauv tsawg zaum nws provokes xeev siab thiab ntuav nyob rau hauv cev xeeb tub poj niam.

Thaum siab noj tshuaj npaum cas dinoprostone muaj peev xwm ntawm tej ntshav siab (vim los ntawm cov vascular du nqaij, thiab cov hlab ntsha), thiab los tsa lub cev kub. Txawm li cas los, nws yuav tsum tau muab sau tseg tias tag nrho cov los yog tsis cai thaum zoo noj cov tshuaj, uas yog, nyob rau pom zoo koob tshuaj rau lub tsev me nyuam ripening.

kinetics

Yuav ua li cas yog lub xam qhovkev kev tig tau tsis medicament "Prepidil"? Cov gel, uas muaj tus nqi ntxiv intracervical tom qab thawj coj ntawm 500 .mu.g nce mus txog ntau tshaj plaws nyob rau hauv concentration cov ntshav tom qab 35-45 feeb. Tom qab ntawd, cov ntsiab lus ntawm active tshuaj yog sai txo mus rau thawj lub theem (tsis hais txog ntawm uterine kev ua si).

Dinoprostone nrog tib neeg albumin uake 73%. Yog li lub active ingredient ntawm cov tshuaj yog muab faib rau tag nrho cov ntaub so ntswg thiab kua nruab nrog cev parturient.

Lom zem ntau dinoprostone metabolized nyob rau hauv lub ntsws, thiab lub raum thiab lub siab. Nyob rau hauv tib neeg cov ntshav thiab zis nrhiav tsawg kawg yog cuaj metabolite prostaglandin E 2.

Feem ntau ntawm cov active ingredient "Prepidila" yog outputted los ntawm ob lub raum, tab sis nyob rau hauv me me - ua ke nrog cov quav.

zaj lus tim khawv

Yog vim li cas kuv yuav tsum tau noj tshuaj "Prepidil"? Cov gel pab tsim kho lub tsev me nyuam ripening. Nws yog tsuas yog siv thaum qhia ua hauj lwm.

Contraindications

Gel rau induction ntawm zog yog tsis siv nyob rau hauv tej yam kev mob uas yog contraindicated rau cov ntev uterine contractions. Cov muaj xws li:

• ntau yam uas cev xeeb tub;
• tsis tuaj kawm ntawv ntawm zoo ntawm lub me nyuam hauv plab lub taub hau;
• los ntawm 6 full-lub sij hawm me nyuam;
• puas los yog tsis yooj yim yug (xws li keeb kwm);
• phais nyob rau lub tsev me nyuam los yog phais plab seem (xws li keeb kwm);
• loj mismatch plab mog niam thiab me nyuam hauv plab lub taub hau;
• me nyuam hauv plab nyuaj siab (ua ntej);
• qhov teeb meem no nyob rau hauv uas phais pab yog preferable;
• teeb nyob rau hauv lub me nyuam hauv plab lub plawv atherosclerosis;
• ntshav tawm hauv qhov chaw mos huam thaum lub sij hawm cev xeeb tub (tsis paub hais tias keeb kwm);
• deev zig (sab kev sib cais);
• txawv txav me nyuam hauv plab kev nthuav qhia ;
• npau taws me ntsis rau cov khoom xyaw gel.

Ceev faj ntshai neeg sawv cev no yog siv nyob rau hauv tawg, kab mob plawv, hepatic kawg, bronchial hawb pob, impaired raum muaj nuj nqi, uas qhia sac, ocular tawg los yog glaucoma.

Tshuaj "Prepidil" (gel): Cov Lus Qhia

Raws li ib tug thawj zaug ntau npaum siv rau tag nrho cov txheem ntawm lub koob txhaj los ntawm kev siv rau qhov no daim ntawv catheter. Nws yog nkag tau rau hauv lub tsev me nyuam kwj dej, uas yog nyob rau hauv qab rau theem ntawm cov internal os.

Thaum lub gel tau nkag mus hauv, ib tug poj niam nyob rau hauv zog yuav tsum ¼ teev dag rau nws rov qab. Qhov no yog tsim nyog nyob rau hauv thiaj li yuav txo tau to ntawm cov tshuaj.

Yog hais tias lub stimulation ntawm ib tug thawj zaug koob tshuaj tsis tshwm sim, tus medicament yog muab dua (tom qab 6 teev). Cov koob tshuaj rau rov thawj coj ntawm cov tshuaj tseem unchanged.

Qhov yuav tsum tau rau lub ntxiv siv cov gel yog txiav txim los ntawm tus soj ntsuam qhov teeb meem no.

Qhov siab tshaj plaws txhua txhua hnub koob tshuaj xam tau tias yog medicament yog 1.5 mg.

dosing

Yuav ua li cas kuv yuav tsum tau siv gel rau induction ntawm zog? Cov lus qhia muaj cov nram qab no incremental cov kauj ruam:

• Unpack muaj menyuam tsis taus koob txhaj thiab catheter.
• Tshem tawm cov koob txhaj ntsis hau.
• Ntxig rau lub koob txhaj hau (rau lwm sab) rau siv raws li ib tug piston.
• Swb tus catheter (nruj nreem) mus rau lub ntsis ntawm cov xiaslias cawv tshwm sim.
• Sau ib tug tshiab niam tag nrho tus txheem ntawm lub syringe.

phiv tshua

Yuav ua li cas yog cov kev phiv los ntawm cov tshuaj yuav ua rau "Prepidil"? Gel nyob rau hauv parturient muaj peev xwm ntawm provoking Titanic uterine contractions (kom nws laus, zaus thiab ntev ntawm cov lus), raws li zoo raws li xeev siab, uterine rupture, ntuav, rov qab mob, raws plab, kub taub hau, npau taws me ntsis kev tshua thiab sov nov ntawm nqaij tawv nyob rau hauv qhov chaw mos.

Nyob rau hauv lub me nyuam hauv plab kev loj hlob ntawm cov tshuaj yuav ua rau kev nyuaj siab, syndrome, raws li zoo raws li hloov lub plawv dhia, txo qhov kev soj ntsuam ntawm tus me nyuam mos lub xeev ntawm lub Apgar tau rau 7 cov ntsiab lus. Ntawm lwm yam, cov kev siv ntawm cov tshuaj yog tsis tshua muaj pom tau hais tias, tab sis tseem ua rau stillbirth.

Tshuaj "Prepidil" (gel): xyuas thiab tus nqi

Tus nqi ntawm cov nyiaj yog heev siab heev. Ib tug koob txhaj nrog lub gel yuav tau muas rau 580-650 rubles. Nws yuav tsum tau muab sau tseg tias kev siv ntawm cov tshuaj no yuav tsum tau xwb nyob rau hauv lub tsev kho mob.

Cov kws kho mob hais tias kev siv ntawm "Prepidila" yuav tsum thawj ntsuam xyuas kev ruaj ntseg ntawm lub plab mog ntawm cov poj niam thiab me nyuam hauv plab lub taub hau loj. Yog hais tias lawv tsis phim, ces cov tshuaj tsis siv.

Raws li rau cov neeg mob, cov kev kawm neeg sawv cev muaj peev xwm ua rau ib tug lossis loj npaum li cas ntawm cov kev phiv, xws li txoj sia me nyuam. Yog li ntawd, feem ntau ntawm lawv tsis kam mus siv no gel, tshwj xeeb tshaj yog tom qab ncav 35 xyoo ntawm lub hnub nyoog.