"Nimesulide" tshuaj. Cov lus qhia rau kev siv, tiag tiag counterparts

Mob - yog ib yam ntawm cov kev sim ntawm lub cev mus rau nyiam cov xim uas tus neeg, hu rau cov kev pab. Yog li ntawd tsis ncaj ncees lawm uas ib yam dab tsi "nyob rau hauv lub Danish nceeg vaj", thiab cov kev pab ntawm lub cev yog tsis txaus rau kev txhim kho qhov teeb meem, peb yuav tsum tau kev pab los ntawm sab nraum.

Consumer kws ua lag luam ntawm Lavxias teb sab Federation hais pua pua ntawm cov tshuaj los pab cov neeg paub daws qhov mob. Tag nrho cov tshuaj sib txawv muaj pes tsawg leeg, tau thiab mechanism ntawm lub hwj. Ib tug ntawm qhov zoo tshaj yog cov tshuaj los ntawm cov pab pawg neeg uas tsis yog-tshuaj anti-inflammatory siv tshuaj. Cov lawv yog cov ncua kev kawm ntawv thiab cov ntsiav tshuaj "Nimesulide".

Qauv thiab pes tsawg leeg

Round ntsiav tshuaj muaj ib tug lenticular zoo. Nyob rau hauv cov xim tej zaum yuav daj ntseg daj los yog tsuas yog daj. Lub ntsiab active tivthaiv - ib yam khoom uas Nimesulide nyob rau hauv txhua ntsiav tshuaj - 100 mg. Los ntawm ib tug xov tooj yuav hu ua ntxiv microcrystalline cellulose, starch (maize), sodium cov hmoov txhuv nplej glycolate, colloidal silicon dioxide.

Nyob rau hauv tas li ntawd, cov tshuaj no yog muaj rau cov tau txais kev pab nyob rau hauv daim ntawv ntawm cov hmoov rau ncua kev kawm ntawv "Nimesulide." Muaj pes tsawg leeg yog tib yam li hais tias ntawm cov ntsiav tshuaj, txhua 100 mg sachet ntsiab active tivthaiv.

pharmacodynamics

Nimesulide xyua cheeb cyclooxygenase-2, cyclooxygenase-1, nws cov nyhuv yog mus rau ib tug npaum li cas tsawg raws li. Nyob rau hauv no hais txog, cov inhibition ntawm prostaglandins synthesis cai provoked inflammatory cov tshuaj tiv thaiv. Txawm li cas los, tus tsim ntawm prostaglandin-hom ntxawg nimesulide niamntiav NW nyuam qhuav perceptible nyhuv, uas ua rau tsawg heev collateral paub txog tus digestive system.

Nyob rau hauv tas li ntawd, lub zoo kev txiav txim ntawm nimesulide manifested nyob rau hauv inhibition ntawm cov tsim ntawm dawb radicals. Txawm li cas los, cov kev ntawm hemostasis thiab phagocytosis tsis raug kev txom nyem los ntawm no substance. Lub mechanism ntawm anti-inflammatory nyhuv sib sib zog tsa medicament occupies loj qhov chaw thiab nws muaj peev xwm mus suppress qhov kev tso tawm ntawm myeloperoxidase (nyob rau hauv ntau inflammatory kab mob yuav ua rau cov ntaub so ntswg kev puas tsuaj, nws yog ib tug ntawm cov tshaj plaws yog diagnostic yam ntxwv indicative ntawm tej mob plawv los yog mob stroke).

Indications rau kev siv

Dav txaus duav txhua yam ntawm cov tshuaj "Nimesulide". Nyob rau dab tsi ua rau cov tshuaj no? Vim hais tias cov tshuaj muaj nyob rau hauv tib txoj nyhuv - antioxidant, analgesic, antipyretic thiab anti - ces nws yog muab nrog ib tug xov tooj ntawm inflammatory kab mob. Pib siv yeeb tshuaj thiab nyob rau hauv lub xub ntiag ntawm osteoarthritis (mob ob leeg kab mob nyob rau hauv thawj qhov chaw puas articular pob txha mos), tendinitis (o ntawm txog leeg thiab cov nqaij mos degeneration), bursitis (o ntawm lub qog ua kua hnab, prevails nyob rau hauv cov pob qij txha).

Zoo tau qhia "nimesulide" nyob rau hauv cov kev kho mob ntawm kev mob caj dab rheumatoid, ntxiv-articular rheumatic kab mob. Ntse sib ntaus sib tua tiv thaiv kab mob cov kab mob uas yog nrog inflammatory dab. Heev feem ntau, "Nimesulide" ntsiav tshuaj siv nyob rau hauv Gynecology, cov kev kho mob ntawm kev raug mob ntawm txawv keeb kwm. Cov neeg mob hais zoo tshem tawm ntawm kev mob thaum lub sij hawm postoperative kev ncaj ncees.

Contraindications "nimesulide"

Txij li thaum lub medicament hais txog ib tug pab pawg neeg ntawm cov niaj hnub National lub rooj sib tham Square, nws muaj heev uas nws kim heev daim ntawv teev cov contraindications. "Nimesulide" (los ntawm dab tsi yuav pab kom cov tshuaj - tau los sib tham yav tas los) yuav tsum tsis txhob coj cov neeg uas muaj hypersensitivity rau tej tivthaiv nyob rau hauv nws muaj pes tsawg leeg. Tsis tshuaj muab rau cov neeg cov neeg mob uas muaj keeb kwm tshwm sim hepatotoxic tshua thiab npau taws me ntsis tshua ua rhinitis, bronchospasm, urticaria (nrog tshuaj aspirin los yog lwm yam narcotics yuav muab cov neeg sawv cev ntawm cov pab pawg neeg).

Contraindications rau kev siv ntawm lub medicament yog muaj tej erosive-ulcerous txhab ntawm lub digestive system, cov nyiam tsim los ntshav ntawm txhua lub hauv paus chiv keeb (t. E. Variations nyob rau hauv lub hauj lwm ntawm cov ntshav txhaws).

Tshuaj "Nimesulide" qhia txwv tsis pub cov neeg mob uas raum, hepatic, mob insufficiency. Cov neeg mob uas "aspirin" kho hawb pob, haus dej cawv thiab yeeb tshuaj dependence thiab tsis noj cov tshuaj.

Tsis txhob muab cov tshuaj nyob rau hauv cov neeg mob, yog hais tias tus neeg mob yog muaj zog lub cev kub los yog lwm yam kab mob khaub thuas zoo li cov tsos mob muaj cai. Nyob rau hauv tas li ntawd, nws yog tsis tsim nyog rau coj "Nimesulide" cov me nyuam, cev xeeb tub thiab lactating cov poj niam.

Tau sab tshua "nimesulide"

Daim ntawv thov ntawm tus medicament yuav ua rau ib tug xov tooj ntawm cov kev phiv los ntawm ntau yam nruab nrog cev thiab tshuab ntawm tib neeg lub cev.

Cov feem ntau tshua yog sau cia los ntawm lub digestive system, thiab lawv yog manifested los ntawm xeev siab, ntuav, raws plab, flatulence, thiab cov kev loj hlob ntawm gastritis. Tsawg feem ntau tshwm sim hnyuv los ntshav, mob rau sab hauv kom txog rau thaum perforation. Qee zaus koj yuav hnov txog dyspepsia, stomatitis, mob plab.

Yuav ua "nimesulide" sab txiav txim los ntawm lub hepatobiliary system, feem ntau manifested nyob rau hauv nce siab enzyme ntau ntau, tsawg kawg yog - nyob rau hauv txoj kev loj hlob ntawm tus kab mob siab (xws li fulminant ..), Cholestatic daj ntseg.

Nyob rau hauv cov tshuaj tiv thaiv ntawm cov hlab plawv system yuav hais tias, yog hais tias muaj yog ib tug khov kho sawv nyob rau hauv cov ntshav siab, cov neeg mob tsis tshua muaj kev txhawj xeeb txog lub plawv palpitations, hemorrhage, kais, ntshav siab jumps.

Mob txeeb system yuav teb mus rau lub tsos ntawm edema (tsis yog feem ntau), tsis tshua muaj - urinary tuav, hematuria, dysuria. Heev tsis tshua tej zaum nws yuav tsim lub raum tsis ua hauj lwm, interstitial nephritis, oliguria.

Tau tshua ntawm lub Cns yog feem ntau manifested los ntawm kiv taub hau, tsis xis nyob, asthenia. Tsawg feem ntau yeej yuav hnov hais txog mob taub hau, somnolence txoj kev loj hlob (kev zoo sib thooj hypnotic pw tsaug zog), Reye syndrome (encephalopathy), hypothermia (lub cev kub txo hauv qab no lub theem yuav tsum tau kom muaj ib txwm metabolism). Qee zaus koj yuav hnov txog tej tshuaj "Nimesulide", raws li nervousness, ntxhov siab vim, npau suav phem.

Nrog kev xav txog cov lymphatic system thiab lub hematopoietic system, "Nimesulide" (Instruction, paramedics xyuas paub meej tias cov ntaub ntawv no) tej zaum yuav tsis tshua ntxias anemia, eosinophilia, tsis tau tsawg yuav muaj thrombocytopenia purpura pantsitopenicheskaya.

Feem ntau yeej tsis, tab sis koj yuav hnov txog cov metabolic teeb (hyperkalemia), lub cev tsis system (meem kev txhawj xeeb, anaphylaxis), cov kabmob uas tsis pom kev (qhov muag plooj tsis pom kev, clouding ntawm lub teb), ua pa, mediastinum (dyspnea, bronchospasm, mob hawb pob tawm tsam). Muaj tshua ntawm daim tawv nqaij thiab subcutaneous cov ntaub so ntswg (tawm hws, khaus, dermatitis, urticaria, erythema, heev tsis tshua muaj - toxic epidermal necrolysis, Stevens-Johnson syndrome).

dosing thiab daim ntawv thov Circuit Court hom

Tus neeg laus cov neeg mob ntsiav tshuaj "nimesulide" kom koj noj ib lub nyob hauv ib lub sij hawm (100 mg) ib hnub ob zaug. Nws yog preferable ua li ntawd tom qab ib tug noj mov thiab haus dej haus kom txaus dej rau ib tug kho. Yog hais tias nws yog ib tug hmoov rau ncua kev kawm ntawv, ces tus txheem ntawm ib sachet yog diluted nyob rau hauv 100 ml ntawm cov dej. Cov me nyuam hluas dua 12 xyoo ntawm lub hnub nyoog yog tsis muaj yuav tsum tau hloov cov tshuaj, thiab cov me nyuam cov tshuaj no rau tau txais txwv tsis pub. Nyob rau hauv cov ntaub ntawv ntawm cov kev kho mob ntawm cov neeg laus cov neeg mob ib koob tshuaj hloov yog tsis ua.

Rau cov neeg kev txom nyem los ntawm hepatic insufficiency, creatine clearance rau hauv lub chav 30-80 ml / min., Cov tshuaj no tsis yog lawm. Yog hais tias qhov taw qhia uas nws txo qis (30 ml / min los yog tsawg dua.) - txwv tsis pub tau txais medicament.

Cov no yog cov ntsiab tswv yim pom zoo rau lub txais tos ntawm cov tshuaj "Nimesulide". Cov tshuaj yog xaiv tsawg kawg zoo, thiab rau lub shortest tau lub sij hawm, uas yuav txo qhov uas yuav muaj kev phiv los. Maximum chav kawm ntawm kev kho uas siv cov "Nimesulide" yuav tsum tsis txhob ntau tshaj 15 hnub.

Ntev ntau npaum: Cov tsos mob, kev kho mob

Noj cov ntsiav tshuaj "Nimesulide", nws yog tsim nyog los ua raws li cov koob tshuaj pom zoo nyob rau hauv cov lus qhia los yog xaiv los ntawm lub mus kawm tus kws kho mob. Self-thawj coj ntawm medicament thiab (los yog) nws uncontrolled siv yuav ua nyob rau hauv overdose. Cov ntau cai nram qab no cov tsos mob: xeev siab, ntuav, los ntshav, mob huam, nkees nkees, nkees, tawg (ntshav siab), inhibition ntawm cov pa muaj nuj nqi, mob raum tsis ua hauj lwm.

Kev kho mob nyob rau hauv cov ntaub ntawv ntawm overdose symptomatic, yog txhawb tus cwj pwm. Antidote nimesulide yog tam sim no uas ploj lawm. Yog hais tias txij li thaum overdosing los yog noj ib siab koob tshuaj medicament yog tsis tau dhau ntau tshaj 4 teev, tus neeg mob yog ib tug lub tsev kho mob pais plab lavage pom zoo txais tos ntxeem tau dej (e.g., tshuab txais carbon nyob rau hauv tus nqi ntawm cov 60-100 mg rau ib tug neeg laus) thiab ib co hom osmotic laxative tshuaj.

Thaum lub sij hawm tag nrho lub sij hawm ntawm kev kho mob yuav tsum tau ua tib zoo saib xyuas los ntawm kws kho mob ua hauj lwm siab thiab raum. Ntaub ntawv hais txog cov tau tshem tawm ntawm nimesulide los ntawm lub cev los ntawm hemodialysis yog tsis muaj. Vim hais tias ntawm cov high degree ntawm yeeb tshuaj losis tswvyim dabtsi rau cov nqaijrog yuam diuresis yog tsis zoo.

Tshwj xeeb cov lus qhia

"Nimesulide" kom tau ib cov tshuaj los ntawm cov chaw muag tshuaj uas tsis yuav tsum tau, txawm li cas los, yuav tsum noj nrog ceev faj. Tsis txhob mus tib seem daim ntawv thov ntawm cov medicament thiab lwm yam uas tsis yog-tshuaj anti-inflammatory kab mob, analgesics attendant. Nrog rau txoj kev loj hlob ntawm cov tsos mob ntawm tus neeg mob, lub siab puas yam ntxwv (xeev siab, ntuav, anorexia, tso zis dub) los yog ua rau kom cov theem ntawm hepatic transaminases daim ntawv thov "nimesulide" yuav tsum tau tso tseg. Yog hais tias muaj yog ib tug taub hau los sis khaub thuas zoo li cov tsos mob, kev kho yuav tsum tau txiav sai li sai tau.

Attentive mus rau nws cov neeg mob yuav tsum tau hais tias nyob rau hauv thaum uas tig mus nrog cov "Nimesulide" noj cov tshuaj uas ua rau kom txoj kev pheej hmoo ntawm txoj hnyuv ulcers thiab los ntshav. Ceev faj tshuaj tshuaj rau cov neeg uas raug kev txom nyem los ntawm ulcerative mob plab los yog Crohn tus kab mob, mob rau sab hauv muaj ib tug keeb kwm ntawm cov neeg laus cov neeg mob.

Cov neeg uas yuav tsum tau "Nimesulide" nrog rau cov tshuaj aspirin nyob rau hauv mob koob tshuaj yuav tsum tau muab ua ke nrog txoj kev kho nrog gastroprotectives.

Txoj kev siv "Nimesulide" (los yog lwm yam NSAID) nyob rau hauv loj qhov ntau thiab ntau tshaj ib tug ntev lub sij hawm ntawm lub sij hawm ua rau yus mus rau ib tug me me nce nyob rau hauv txoj kev pheej hmoo ntawm thromboembolic xwm txheej (stroke, heart attack myocardial infarction, thiab hais txog. N.).

Cov neeg mob uas muaj ntau yam kab teeb meem "Nimesulide" system tej zaum yuav tau tsa xwb yog hais tias tus tsim cov kev pab tshaj txoj kev pheej hmoo ntawm kev phiv.

Lub medicament muaj ib cov nyhuv rau cov neeg kawm ntawv ntawm platelet kev ua si. Cov ntaub ntawv no yog ib qho tseem ceeb rau cov neeg mob kev txom nyem los ntawm hemorrhagic diathesis. Loj txhab ntawm daim tawv nqaij feem ntau tsim thaum lub sij hawm ntev-lub sij hawm siv "nimesulide". Thaum daim tawv nqaij ua pob ua xyua tshwm sim, yuav appreciable kev puas tsuaj rau txheej week los yog lwm yam tsau ces intolerance, tshuaj kho yuav tsum tau txiav.

Txoj kev siv "Nimesulide" cev xeeb tub cov poj niam yuav ua rau muaj mob kaw arterial duct ua ntej nws yuav tsum tau, txo lub ntim ntawm amniotic kua. Tau kev raug mob ntawm intrauterine los ntshav, weakening ntawm zog, lub tsos ntawm edema. Vim li no, tos niam thaum lub sij hawm thawj thiab thib ob trimesters ntawm cev xeeb tub txais tos "Nimesulide" yog tsis pom zoo.

Nws yuav tsum muaj ib lo lus teb rau cov nqe lus nug ntawm seb peb yuav coj lub "Nimesulide" ib txhij thiab haus dej haus cawv, nws yog cuab kev: xws li ib tug ua ke yog tsis tso cai!

analogs

Nyob rau hauv analogs "nimesulide" yog hais txog cov tshuaj los ntawm NSAID pawg uas muaj raws li ib tug lub ntsiab active khoom sib ua zaub mov nimesulide (nqi rau lawv yuav oscillate ntawm kwv yees li tib yam ntau yam tab sis me ntsis hauv qab no nws). Qhov tseem paub thiab feem ntau muab kev kho mob cov neeg ua haujlwm analogs muaj xws li tshuaj "Naiz" (gel, ntsiav tshuaj, ncua kev kawm ntawv), "Nimesil" (hmoov) "Niemiec" (ntsiav tshuaj) 'nimulid "(gel, ntsiav tshuaj, ncua kev kawm ntawv cov ntsiav tshuaj rau ib co kab) .

Tag nrho analogs muaj txaus efficiency thiab muab mus rau nrog rau ntau yam kev mob, inflammatory hnav cim.

nqi ntau

Nqi rau nws tus kheej "Nimesulide" thiab nws cov analogs yog kwv yees li tib yam, txawm tias peb pom tias cov tshuaj nqi ntau mus siv cuag mus rau ib tug ntau ntawm cov tub lag luam. Ntsiav tshuaj "Nimesulide" (20 pcs. Nyob rau hauv ib lub pob) yuav raug nqi 85-90 rubles ib pob. Cov tib tooj ntawm cov ntsiav tshuaj "Naiza" yuav raug nqi 110-140 rubles, "Niemiec" (kuj 20 pcs.) - nyob rau hauv lub 115-134 rubles. Ntim "nimulid" ntawm 30 lub tshuaj nqi 180-220 rubles. Lub volume cov ntsiab lus ntawm lub ntsiab active khoom sib ua zaub mov (Nimesulide) nyob rau hauv tag nrho cov analogs tib yam - 100 mg.

Es tsis txhob ntsiav tshuaj "Nimesulide" (tus nqi qis tshaj) yuav tau, piv txwv li, ib tug slurry "Naiz" nqi 200-300 rubles 60 ml los yog "nimulid" - 75-105 rubles rau tib tus nqi ntawm cov tshuaj. Kuj muaj nyob rau ntau yam ntawm cov kev pab lozenges "nimulid": 20 shares ntawm ib tug nqi 130-155 rubles ib pob.

Tej zaum cov feem ntau kim daim ntawv ntawm kev tso tawm ntawm cov tshuaj nrog nimesulide raws li ib tug lub ntsiab tivthaiv - ib tug hmoov 'Nimesil ". 30 hnab (pob) yuav raug nqi tus neeg muas zaub nyob rau hauv tus nqi ntawm cov los ntawm 560 mus 645 rubles.

Rau cov tshuaj pleev daim ntawv thov yog zoo tshuaj kua nrog nimesulide. Yog li, "Naiz" yuav raug nqi 120-145 rubles rau ib tug raj ntawm 20 g los yog 215-275 rubles (50 g). Gel "nimulid" ib tug me ntsis cheaper: 115-150 rubles ib raj ntim ntawm '30

Nyob rau hauv xaus Kuv xav hais tias cov nram qab no. Qhov kev txiav txim yuav siv "nimesulide", tej analogue los yog lwm yam narcotics yuav muab yuav tsum tau npaum li cas los lub mus kawm tus kws kho mob. Tsuas yog cov kev kho mob kev yuav kom ntsuam xyuas lub hnyav ntawm kev kho mob ntawm lawv cov neeg mob, yuav tau xav txog tag nrho cov uas muaj feem xyuam kab mob, xaiv cov tshuaj ntau npaum xaiv thiab tsim kev npaj khomob nyob rau hauv thiaj li yuav txo tau cov ntxim yuav zoo siv ntawm kev phiv thiab kom tau txais cov feem ntau zoo tau.