Oncomarker CA 125

CA 125 yog suav hais tias yog ib lub cev muaj zog loj glycoprotein, uas yog ib qho antigen. Nws tshwm sim los ntawm derviata hauv coelomic epithelium ntawm fetal cov ntaub so ntswg thiab muaj nyob rau hauv cov cai hauv endometrial cov ntaub so ntswg, mucinous thiab serous uterine kua. Nyob rau hauv cov hlab ntsha, nws tsis nkag mus, tsuas yog thaum muaj kev puas tsuaj ntawm tej qho kev tiv thaiv.

Concentration nyob rau hauv cov ntshav muaj peev xwm muab ob npaug rau lub cev ntu, tshwj xeeb tshaj yog tiv thaiv cov keeb kwm ntawm endometriosis. CA 125 yuav raug nce ntxiv rau thawj peb lub hlis cev xeeb tub. Ib me ntsis nce rau hauv ib tug poj niam uas muaj kev noj qab haus huv yog vim nws cov synthesis hauv plawv, plab kab noj hniav, bronchial epithelium, pericardium, fallopian plawv; Nyob rau hauv cov txiv neej - los ntawm synthesis nyob rau hauv lub epithelium ntawm testes.

Oncomarker meej CA 125 tuaj yeem kuaj qog metastases rau lub hlis ua ntej qhov pib ntawm qhov mob tshwm sim (qhov tseeb). Qhov tseeb no ua rau nws muaj peev xwm soj ntsuam qhov kho cov nyhuv hauv kev kho tus kab mob.

CA 125 cancer marker yog ib qho tseem ceeb ntawm kev kuaj mob qog nqaij hlav hauv zes qe menyuam. Qhov kev ntsuam xyuas no yog xyuas raws li qhov paub tias muaj cov tshuaj ntau ntxiv hauv cov ntshav. Cov tshuaj no qhia txog kev loj hlob ntawm cov qog. Qee tus antigens muaj qee cov tshuaj hormones, cov kua roj (enzymes), cov khoom lwj thiab lwm tus.

Tsom xaj rau Ntawm Tus Neeg Tawm Tsam CA 125

Qhov ntsuas ntawm qhov ntsuas yog 35 units / ml. Kev nce nyob rau theem ntawm kev ua haujlwm (kev qaug zog) yog suav tias yog lub hauv paus rau kev soj ntsuam ntawm tus neeg mob kom thiaj li paub txog kev rov qab kis ntawm qhov kev mob ntsws. Qhov kev nce zuj zus tuaj qhia tau hais tias muaj cov txheej txheem qog thiab muaj kev phiv tshuaj rau kev kho mob.

Kev tsom xam rau ntawm oncoprotein CA 125 muaj qhov tsis tseem ceeb. Raws li cov ntaub ntawv tawm, ob chav nce nyob rau cov ntshav dej, tshwj xeeb tshaj yog rau cov neeg mob hnub nyoog tsib caug tsib, muaj ib qho kev txhim khu kev qha ntawm txoj kev loj hlob ntawm cov qe menyuam.

Thaum noj cov hnoos qis thiab noj mov tas, yuav tsum muaj tsawg kawg yim (dua li, ntawm chav kawm, tsis pub tsawg tshaj kaum ob). Koj tsis tuaj yeem haus dej tshuaj yej, kua txiv lossis kas fes. Nws yog pub siv dej.

Ntxiv antigen nyob rau hauv serum qhia cancer:

- nyob rau hauv lub txiav, lub caj pas mammary;

- zes qe menyuam, endometrium, lub tsev me nyuam, txoj hlab qe menyuam ;

- mob siab, mob plab, quav;

- lub ntsws;

- lwm malignant neoplasms.

Ib qho tseem ceeb ntxiv hauv cov cim qhia tau rau cov qog nyob rau hauv txoj hnyuv quav, lub mis thiab lub qe paj paws. Yog li, nws tseem tsis tau los tshawb pom kev mob cancer ntawm CA 125 ib leeg. Yog li ntawd, yuav tsum tshawb nrhiav ntxiv.

Ib qho kev nce me ntsis hauv CA 125 tuaj yeem pom cov mob gynecological neoplasms ntawm kev phais, zoo li cov txheej txheem inflammatory uas muaj cov tshuaj ntxiv. Rau cov kab mob thiab tej yam kev mob, nrog ib tug me ntsis nce nyob rau theem ntawm antigen, muaj xws li:

Cov hlwv ntawm zes qe menyuam;

- endometriosis;

- o nyob rau hauv cov yav tsaus ntuj;

- pleurisy, peritonitis;

- STI;

- kev coj khaub ncaws;

- cirrhosis, mob kab mob siab ntev;

- mob pancreatitis ntev;

- Ib co kab mob autoimmune.

Nrog rau txoj kev loj hlob ntawm benign qog thiab inflammatory dab, mob marker CA 125 tsis siab tshaj 100 U / ml. Cov kev soj ntsuam tseem ceeb rau kev ntsuam xyuas kev siv tshuaj kho ntawm txoj kev kho mob uas siv, thiab kev kuaj kom paub meej txog kev rov ua kom qis ntawm endometriosis.

CA 125 yog xam cov qog nqaij hlav ntawm xaws hnyuv quav nyob hauv lub zes qe menyuam. Nws qhov Performance index ntawm 150-200 U / ml qhia tias kev koom tes ntawm serous membranes hauv cov pathology. Nws yog ib qho tseem ceeb los soj ntsuam nws cov concentration hauv kev txheeb xyuas cov txiaj ntsim ntawm kev kho mob phais thiab kws khomob. Nyob rau hauv rooj plaub ntawm ib qho chaw pw hauv lub nrig, nws cov ntshav suav poob mus rau kaum units ib lub milliliter. Ib qho kev nce rau 35 units / ml qhia tau hais tias muaj tus txheej txheem rov muaj dua.