Ntsiav tshuaj "Lenuksin": xyuas, cov lus qhia rau kev siv, hauj lwm, analogues, nqe

Yuav ua li cas muaj kev nyuaj siab rau lawv tus kheej? Teb rau lo lus nug no yog heev yooj yim. Tom qab tag nrho, kom tau tawm ntawm lub xeev no tsis muaj kev pab los ntawm cov tub txawg muaj peev xwm ntawm ib tug ob peb. Nyob rau hauv no kev twb kev txuas, peb pom zoo kom tham tau ib tug kws kho mob, uas tom qab tsa txoj kev kho.

lus qhia dav dav

Kev nyuaj siab yog hu ua ib tug puas siab puas ntsws tsis meej, uas yog yus muaj los ntawm cov uas tsis muaj mus ob peb vas, xav tsis meej (yeej los ntawm ib tug phem heev saib ntawm txhua yam uas tshwm sim, tsis zoo kev txiav txim, thiab hais txog.), Tsav ruamqauj, raws li zoo raws li lub poob ntawm lub peev xwm los muaj kev xyiv fab.

Nws yuav tsum tau muab sau tseg tias nyob rau hauv lub xeev no, ib tug neeg uas nws txo qis self-esteem, poob kev txaus siab nyob rau hauv lub neej thiab ua hauj lwm. Nyob rau hauv Feem ntau, ib tug neeg mob uas yog kev txom nyem los ntawm kev nyuaj siab tej zaum yuav pib ua phem rau haus dej haus cawv, yeeb thiab lwm yam psychotropic tshuaj. Feem ntau cov neeg no muaj suicidal tendencies.

Niaj hnub no, kev nyuaj siab yog kho tau. Nyob rau hauv tus txheej txheem ntawm psychotropic tshuaj tej zaum yuav muab rau ib tug neeg mob txoj kev kho. Sau lawv heev uas nws kim heev. Uas yog vim li cas lawv yuav tsum tau xaiv tsuas yog ib tug tej tus kws khomob tshwjxeeb.

antidepressant

Cov feem nrov tshuaj rau kev puas hlwb yog ib qho kev nyuaj siab "Lenuksin". Nyob rau hauv no tsab xov xwm, peb yuav qhia rau koj txog cov neeg nyob rau hauv uas nws yog taw, yog hais tias nws muaj tej yam contraindications thiab kev phiv, thiab dab tsi yog nws muaj nqis, qhov kev tso tawm daim ntawv no, cov qauv, seb puas muaj analogues ntawm medikmenta thiab thiaj li nyob.

Muaj pes tsawg leeg ntawm yeeb tshuaj, nws ntim thiab hauv daim ntawv ntawm

Ua ntej kuv qhia rau koj txog yuav ua li cas cov tshuaj "Lenuksin" ua, uas xyuas yuav tsum tau muab nthuav hauv qab no, yuav tsum tau muab nws tso tawm rau daim ntawv. Qhov cuab yeej no yog muag nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, uas yog coated nrog ib tug zaj duab xis txheej.

Cov tshuaj no muaj cov active tivthaiv xws li escitalopram oxalate. Sib nrug los ntawm nws, nyob rau hauv cov ntsiav tshuaj thiab koom haum pab hais muaj nyob rau hauv daim ntawv ntawm microcrystalline cellulose, croscarmellose sodium, talc, microcrystalline cellulose silitsinizirovannoy, siliconized microcrystalline cellulose thiab magnesium stearate.

Tshuaj "Lenuksin", uas yog theej nqi siab, muag nyob rau hauv polypropylene vials (tej zaum nyob rau hauv cov hlwv), muab tso rau hauv ib lub thawv. Txhua lub thawv muaj 28 los yog 14 ntsiav tshuaj.

Lub pharmacological yam ntxwv ntawm antidepressant

Tshuaj "Lenuksin", xyuas uas muaj ntau tshaj li zoo, yog ib qho kev nyuaj siab. Qhov no SSRIs, uas tsub kom lub concentration ntawm cov neurotransmitters nyob rau hauv lub synaptic cleft, thiab prolongs thiab tej cov nyhuv rau postsynaptic serotonin receptors.

Tus tam sim no medicament caij suab tsis khi rau alpha-adrenoceptors, m-cholinergic receptors, opioid, serotonin, benzodiazepine, dopamine thiab histamine receptors.

Xyaum qhia tau hais tias lub antidepressant nyhuv rau cov neeg mob pib tsim tsuas yog tom qab 2-4 lub lis piam tom qab pib ntawm txoj kev kho. Qhov siab tshaj plaws them nyiaj rov qab yog lub txiaj ntsim ntawm ntshai teeb meem no feem ntau yog tau los ntawm ib tug ob peb lub hlis.

tshuaj txhais tau tias

Raws li cov tshuaj no yog absorbed, "Lenuksin"? nyob rau kev siv ntawm antidepressant phau ntawv hais tias nws haum yog yus noj kom tsawg. Lub bioavailability ntawm cov tshuaj yog kwv yees li 80%. Qhov siab tshaj plaws ntshav concentration yog mus txog tom qab 4 teev ex. medicament Ntshav protein losis tswvyim dabtsi yog kwv yees li 56%.

Antidepressant metabolism tshwm sim nyob rau hauv lub siab (tsim active didemetilirovannyh thiab demethylated metabolites). Lub ib nrab-lub neej tom qab ntau thawj coj yog kwv yees li 30 teev.

Indications rau kev siv ntawm antidepressants

Nyob rau hauv tej rooj plaub, ib tug yeeb tshuaj "Lenuksin"? Cov lus qhia rau kev siv, cov lus teb qhia hais tias nws yuav tsum tau tsuas yog siv raws li nram qab hloov:

• kev nyuaj siab, nws yog ib yam mob loj heev los yog muaj mob loj tsawv daim ntawv;
• Social ntxhov siab vim teeb meem (social phobia hais tias yog);
• panic teeb meem nrog agoraphobia, los yog tsis muaj nws;
• generalized kev ntxhov siab vim teeb meem.

Contraindications rau kev siv ntawm antidepressants

Kev kho mob nrog antidepressants nyob rau hauv txhua rooj plaub yuav tsum tau nqa tawm nyob rau hauv cov nram no tej yam kev mob thiab yam:

• nrog ib tug simultaneous kom tsawg ntawm Mao inhibitors;
• nyob rau hauv thaum yau thiab thaum tiav hluas mus txog 18 xyoo;
• npau taws me ntsis rau cov medicament los yog nws cov yam;
• lub tshaj los yog sucrase isomaltase, qabzib-galactose malabsorption thiab fructose intolerance.

ceev faj siv

Ntsiav tshuaj "Lenuksin" yuav tsum tau muab rau cov neeg mob raum tsis ua hauj lwm yog tsis tshua muaj cautiously, mob ntshav qab zib, hypomania, los ntshav ib txwm, mania, mob npuas paug thiab pharmacologically uncontrolled qaug dab peg.

Tsis tas li ntawd zoo heev yuav tsum tau siv cov tshuaj no rau kev nyuaj siab nrog suicidal tendencies, thaum uas tau txais cov tshuaj kom txo tau qhov pib thiab metabolized los ntawm isoenzymes ntawm CYP2C19, cov neeg laus thiab, ua ke nrog ethanol.

Tshuaj "Lenuksin": cov lus qhia rau kev siv

Qhov no tshuaj yog tso tawm nyob rau hauv ib tug muag tshuaj los ntawm cov tshuaj xwb. Tom qab tag nrho, nws muaj peev xwm tsuas taw kws txawj uas muaj qhov tsim nyog tsim nyog.

Cov tshuaj ntawm cov tshuaj thiab nws cov multiplicity ntawm kev siv nyob rau hauv lub qhov kawg thiab hom sib txawv. Raws li cov kev qhia ntawv, hais tias txhais tau tias yuav tsum tau siv ib hnub ib zaug ua ntej, tom qab los yog nyob rau hauv nruab nrab noj mov.

• Kev nyuaj siab, muaj hnyav los yog nruab nrab lawm.

Nyob rau hauv cov ntaub ntawv no, cov tshuaj "Lenuksin", uas yog theej nqi siab them nyob rau hauv 10 mg ib zaug ib hnub twg. Nyob ntawm seb cov tshuaj tiv thaiv ntawm (tus neeg) ntawm tus neeg mob, cov tshuaj yuav tau nce mus rau 20 mg ib hnub twg. Tom qab lub disappearance ntawm cov tsos mob ntawm kev nyuaj siab yuav tsum kho mob rau 6 lub hlis, kom txhim kho tau qhov tshwm sim.

• Ceeb tsis meej nrog agoraphobia, los yog tsis muaj nws.

Thaum lub sij hawm thawj lub lim tiam ntawm kev kho mob rau tus neeg mob yuav tsum tau txhaj koob tshuaj sib npaug zos rau 5 mg ib hnub twg. Nyob rau hauv lub neej yav tom ntej nws yuav tsum tau nce raws nraim ob zaug. Nyob ntawm seb cov tshuaj tiv thaiv npaum li cas ntawm cov tshuaj tus neeg mob yuav ua rau lub siab tshaj plaws, i.e. mus rau 20 mg ib hnub twg. Qhov no kev kho mob kav ob peb lub hlis.

• Social phobia los yog muaj kev ntxhov siab tsis meej.

Nyob rau hauv xws mob tshuaj "Lenuksin" (txhais medicament) yog muab nyob rau hauv ib tug npaum li ntawm 10 mg ib zaug ib hnub twg. Weakening tej yam tshwm sim ntawm txawv tshwm sim nyob rau hauv kwv yees li 2-4 lub lis piam. Tom qab, cov tshuaj yuav raug muab txo rau 5 mg ib hnub twg los yog nce mus rau 20 mg ib hnub twg.

Vim hais tias kev sib raug zoo phobia yog ib tug kab mob nrog ib tug mob kawg, lub duration ntawm lub tshuaj kawg yuav tsum muaj tsawg kawg yog 12 lub lis piam. Yuav kom tiv thaiv tsis tshua mob heev ntawm tus kab mob, cov kws muaj txuj yuav tau muab re-kho mob, uas yuav tsum tau nqa tawm tsis pub dhau 6 lub hlis.

Los ntawm txoj kev, ua ntej lub sij hawm teem tseg ntawm cov tshuaj tus kws kho mob yuav tsum tau txawv kev phobia nrog li ib txwm ntshai los yog shyness.

• Generalized kev ntxhov siab vim teeb meem.

Raws li prescribers "Lenuksin" thaum xa mus rau qhov mob? Guest kws txawj hais tias nyob rau hauv thaum pib ntawm cov kev kho mob yog ib tug txhais tau tias yuav tsum tau siv nyob rau hauv ib tug npaum li ntawm 10 mg ib zaug ib hnub twg. Yog hais tias tsim nyog, ntau npaum yuav muab ntau zog rau ib tug tshaj plaws, i.e. mus txog 20 mg ib hnub twg. Tau ntev-lub sij hawm kev siv ntawm cov tshuaj (6 lub hlis los yog ntev dua).

Cov neeg nyob rau hauv cov laus hnub nyoog (tshaj 65 xyoo) yuav tsum tau siv nyob ib nrab ntawm cov ib txwm koob tshuaj yog qhov tsawg, uas yog, 5 mg thiab 10 mg, feem (nyob rau hauv lub hnub).

Cov kev taw qhia nyob rau kev siv ntawm cov tshuaj

Nyob rau hauv lub raum tsis ua hauj lwm hauj sim heev koob tshuaj hloov yog yuav tsum tau. Rau cov neeg mob nrog ib tug zoo xws li cov kab mob, tab sis nyob rau hauv kev mob loj daim ntawv, cov tshuaj yog tshuaj rau lawv nrog huab ceev faj.

Thaum lub teeb los yog muaj mob loj tsawv siab tsis ua hauj lwm pom zoo ntau npaum thaum lub sij hawm thawj ob lub lim piam ntawm txoj kev kho yuav tsum muaj 5 mg ib hnub twg. Nyob rau hauv lub teb ntawm cov neeg mob volume ntawm yeeb tshuaj muaj peev xwm muab tau ntau zog ob zaug.

Rau cov neeg mob uas txo ua si ntawm CYP2C19 isozyme thawj zaug koob tshuaj medicament kuj 5 mg ib hnub twg. Yog hais tias tsim nyog, nws yuav muab ntau zog mus rau 10 mg.

Thaum txiav ntawm txoj kev kho yog txo tus nqi ntawm cov tshuaj maj tshaj 1-2 lub lis piam. Qhov no yog tsim nyog nyob rau hauv kev txiav txim kom tsis txhob muaj qhov tshwm sim ntawm ntsoos ntsoos syndrome.

tus neeg mob ntawm overdose

Kuj muaj coob tus neeg hais cov nqe lus nug ntawm seb thiab yuav ua li cas koj yuav tua nyuaj siab rau lawv tus kheej? Yog hais tias tus mob rau ib ntev lub sij hawm, nws yuav tsis ua li cas tsis recourse mus rau cov kws txawj. Tom qab tag nrho, cov neeg mob yuav tsum tau siv ntawm antidepressants, uas yuav tsum tau xaiv ib tug kws kho mob.

Yog hais tias ib tug neeg siv lub hais tias txhais tau hais tias kom tau qhov ntim, ces tsis ntev nws yuav muaj cov nram qab cov tsos mob ntawm overdose: pa nyuaj siab, tshee, convulsions, kiv taub hau, tachycardia, ntxhov siab, rhabdomyolysis, tsaug zog, metabolic acidosis, kiv taub hau, arrhythmia, ECG hloov, ntuav thiab hypokalemia .

Nws yuav tsum tau muab sau tseg hais tias coma thiab tuag nyob rau hauv cov ntaub ntawv ntawm ib tug overdose yog tsis tshua muaj heev. Qhov no yuav tshwm sim tau xwb thaum kev txhim kho kev txais tos ntawm ib tug npaj nrog lwm yam tshuaj.

Raws li ib tug kho mob siv nyob rau hauv tus neeg mob ntawm overdose txhawb thiab symptomatic txoj kev kho ntawm pais plab lavage thiab txaus oxygenation. Nyob rau hauv tas li ntawd, tus saib lub lag luam ntawm cov hlab ntsha thiab lub plawv, thiab lub pa system.

Tshuaj "Lenuksin": phiv

Sab los ntawm kev tau txais hais tias cov nyiaj feem ntau tshwm sim thaum pib ntawm txoj kev kho. Tom qab ib co sij hawm no, lawv yuav ua tsawg mob siab heev.

• Digestive system: tsis qab los noj mov, xeev siab, saj ntxaug, ntuav, qhov ncauj qhuav, raws plab, muaj zog qab los noj mov, thiab cem quav.
• Lub paj hlwb: txob taus, mob taub hau, ntxhov siab vim, kiv taub hau, ntxhov siab, tsis muaj zog, pom tau qhov sib cuam tshuam, insomnia, ntshai tsam, tsaug zog, depersonalization, convulsions, delusions, co, serotonin syndrome, zog mob, hallucinations, thiab tsis meej pem.
• Me nyuam system: impotence, txawv txav ejaculation, raws li zoo raws li kev ua txhaum ntawm lub cev ntas.
• Ntawm daim tawv nqaij: angioedema, tawm hws ntau zog, purpura, ecchymosis, pruritus thiab daim tawv nqaij sawv pob,
• General: hyperthermia thiab tsis muaj zog.
• Mob txeeb system: urinary tuav tseg.
• Lub plawv thiab cov hlab ntsha: orthostatic hypotension.
• Metabolism hauv: tsis txaus secretion ntawm ADH.
• Licas: arthralgia thiab myalgia.
• Kuaj kev tshawb fawb: Cov kev hloov hauv daim siab muaj nuj nqi, electrocardiogram thiab hyponatremia.
• Kev ua xua: sij hawm ntawm anaphylactic tshua.

Thaum cov tsos thiab aggravation ntawm ib yam ntawm cov saum toj no sab los koj yuav tsum tam sim ntawd qhia rau koj tus kws kho mob.

Kev pub niam mis thiab cev xeeb tub

Kuv yuav siv cov tshuaj "Lenuksin" thaum lub sij hawm cev xeeb tub? Guest cov kws txawj hais tias, nws yog tsis pom zoo vim tsis muaj ntaub ntawv nyob rau hauv kev ruaj ntseg thiab cov hauj lwm zoo ntawm cov tshuaj no, siv nws thaum lub sij hawm hnub tus me nyuam. Ntxiv mus, kom tsawg ntawm cov tshuaj yuav tsum tau txiav thaum lub sij hawm lactation.

Tib mus kho mob nrog rau lwm cov tshuaj

Psychotropic tshuaj, daim ntawv teev cov uas yog heev kim heev, nws yuav tsum tsuas muab lub sij hawm teem ntawm cov kws txawj thiab nruj me ntsis nyob rau hauv nws cov kev tswj.

Medicament "Lenuksin" txwv tsis pub muab ua ke nrog Mao inhibitors, raws li qhov no tej zaum yuav ua rau kom txoj kev loj hlob ntawm serotonin syndrome. Nws yuav tsum tau muab sau tseg tias cov kev txais tos ntawm no txhais tau tias cov hluas (nyob rau hauv lub hnub nyoog ntawm 24 ex-xyoo) muaj kev puas hlwb kev ntshawv siab thiab kev nyuaj siab tsub kom qhov tshwm sim ntawm suicidal ideation thiab suicidal tus cwj pwm.

Nrog rau cov simultaneous siv tshuaj nrog lithium thiab tryptophan mob nce ntawm cov thawj cov nyhuv ntawm cov tshuaj

Co-thawj coj ntawm cov tshuaj nrog Hypericum perforatum ua rau ib tug nce tus naj npawb ntawm cov kev phiv.

Tib mus siv ntawm ib tug antidepressant nrog indirect anticoagulants, thiab lwm yam neeg uas muaj feem xyuam rau cov ntshav txhaws, tej zaum yuav ua rau kom muaj kev cuam tshuam ntawm tus txheej txheem. Nyob rau hauv xws li mob, nyob rau thaum xaus ntawm kev kho mob yuav tsum xyuas ntawm tus neeg mob thiab cov ntshav mob.

Cov neeg mob uas tau hais tias cov tshuaj nrog serotonergic agents, serotonin syndrome zaum yuav tshwm sim.

Sis nrog ethanol

Lub medicament "Lenuksin" tsis tuaj nrog ethanol pharmacokinetic los yog pharmacodynamic sis raug zoo. Tab sis qhov no tsis tau txhais hais tias antidepressant yuav noj ua ke nrog haus dej haus cawv. Thaum lub sij hawm kev kho mob, tus neeg mob yog ib qho zoo mus tso tseg rau qhov kev siv ntawm tej dej cawv.

Nws yuav tsum tau muab sau tseg tias thaum lub sij hawm lub sij hawm ntawm kev kho mob rau tus neeg yuav tsum caiv txhob tsav tsheb tsheb thiab hauj lwm yus ua hauj lwm hom uas yuav tau nce psychomotor ceev ntawm cov tshuaj tiv thaiv thiab concentration.

Nqe thiab analogues ntawm cov tshuaj

Yuav ua li cas npaum li cas yog cov tshuaj antidepressants "Lenuksin"? Tus nqi ntawm cov tshuaj no tej zaum yuav txawv thiab nyob ntawm seb tus npoo. Qhov nruab nrab nqi ntawm cov tshuaj yog 990 Lavxias teb sab rubles ib 28 daim. Pom zoo, nws yog heev ib qho kim tshuaj, uas muaj nyiaj tsis rau sawv daws. Nws yuav tsum raug sau tseg hais tias nws yog tsis tshua muaj muag nyob rau hauv pharmacies. Raws li ib tug txoj cai, tom qab qhov kev nthuav qhia ntawm ib tug tshuaj, cov kws tshuaj muaj kom noj tshuaj, uas feem ntau yog los nyob rau hauv ib ob peb hnub.

Yog li ntawd yuav ua li cas yog tias ib tug neeg mob twb kho ib qho kev nyuaj siab, tab sis nws tsis muaj tej nyob rau hauv Tshuag los yog nyob rau kev txiav txim? Nyob rau hauv cov ntaub ntawv no, kws txawj pom zoo kom yuav nws counterpart. "Lenuksin" muaj lawv nyob rau hauv es loj qhov ntau. Xav txog daim ntawv teev cov xws tshuaj tam sim no:

• "Escitalopram oxalate".
• "Miratsitol".
• "Escitalopram-Teva".
• "Santsipam".
• "Escitalopram Sandoz."
• "Selectors".
• "Escitalopram".
• "Tsipraleks".
• "Elitseya".
• "Eysipi".

Cov nyiaj no yuav ua tau raws li kim li tus thawj, thiab pheej yig dua. Txawm li cas los, tag nrho lawv khiav lag luam nyob rau hauv tib lub ntsiab cai raws li cov tshuaj "Lenuksin". Ntxiv mus, lawv kuj muaj nyob rau ntawm hwj tshuaj. Yog li ntawd, yuav tau tom lub tsev muag tshuaj nyob rau hauv nws cov tib tug yam koj tsis.

Xyuas ntawm medicament

Tam sim no uas koj paub ntau npaum li cas antidepressant "Lenuksin" (nqe). Xyuas txog nws yog mixed. Ib tug neeg hais tias nws copes zoo nrog cov paub tab, thaum lwm tus neeg hais lus ntawm nws ineffectiveness.

Zoo xyuas ntawm no medicament muaj cov ntaub ntawv uas nws sai sai relieves kev ntxhov siab vim teeb meem, pab txoj kev mus ob peb vas thiab zoo. Cov neeg mob kuj hais tias noj antidepressants ntawm pom zoo koob tshuaj tau tso cai rau lawv tau tshem ntawm kev phobia, ntshai tsam thiab kev nyuaj siab. Thiab qhov no ua rau mob tsawv tom qab discontinuation ntawm cov tshuaj.

Raws li rau qhov tsis zoo xyuas, qhov ntau lawv yog txuam nrog rau sab los nlichiem. Nyob rau hauv ib co neeg mob, xeev siab, ib txhia mob taub hau, thiab ib co ho tsis saib tej nyhuv ntawm kev kho mob.