Mefenamic acid

"Mefenamic acid" - ib tug yeeb tshuaj lug siv nyob rau hauv arthrology, kev kho mob ntawm kis kab mob inflammatory xwm, relieving cov tsos mob ntawm lub hlwb.

Qhov no tshuaj belongs rau cov pab pawg neeg ntawm pharmacological tshuaj fenamates - tshuaj muaj anti-inflammatory nyhuv. "Mefenamic acid" tau tsim muaj nws tus kheej raws li ib qho zoo heev antipyretic thiab analgesic.

Cov tshuaj muaj ib tug complex mechanism ntawm qhov kev txiav txim yuav ncaj qha kev koom tes nyob rau hauv lub inflammatory kev tig cev. "Mefenamic acid" (active tshuaj) thiaj li synthesis ntawm tej tshuaj (kev sib kho), uas muaj xws li cov prostaglandins, kinin, serotonin. Nyob rau hauv tas li ntawd, nws ho thiaj li cov kev ua ntawm lub lysosomal proteolytic enzymes, koom ncaj qha nyob rau hauv thawj ob theem ntawm o: exudation, loj hlob. Lwm yam los ntawm cov tshuaj no muaj xws li: cov stabilization ntawm cell week thiab protein ultrastructures, txo vascular permeability thiab o ntawm cov ntaub so ntswg, ua cov kev ua ntawm serotonin, nce kuj hlwb, stimulation ntawm lwm dab. Analgesic tshuaj nyhuv yog qhov ncaj ntxim rau cov central mechanism ntawm qhov mob rhiab heev, raws li zoo raws li lub zos txiav txim nyob rau hauv inflammatory kom pom tseeb. Antipyretic khoom no txuam nrog rau hauv tib neeg thaiv cov hlab prostaglandin synthesis, teebmeem rau lub thermoregulatory chaw nyob rau hauv lub hlwb. Lwm feature yog mus tsim kho lub zus tau tej cov interferon, uas ncaj qha tej cov proliferative thaj chaw ntawm lub active tshuaj.

Mefenamic acid muaj ib tug txaus siab haum coefficient. Qhov siab tshaj plaws concentration yog tiav tom qab ob mus rau plaub lub sij hawm tom qab txais tos. Cov theem ntawm cov tshuaj nyob rau hauv cov ntshav yog ib txwm proportional rau nws koob tau txais. Thauj nyob rau hauv cov hlab ntsha ntawm cov tshuaj tshwm sim los ntawm ruaj rau albumin. Lub ib nrab-lub neej ntawm lub active tshuaj yog peb teev. Kwv yees li rau caum feem pua yog tas nyob hauv cov zis nyob rau hauv zoo unaltered daim ntawv, nees nkaum-tsib - nrog rau cov quav.

"Mefenamic acid" muaj ib tug dav txaus spectrum ntawm kev ua si, uas yog piav los ntawm ib tug plurality ntawm cov teebmeem uas renders active neeg sawv cev. Kab mob loj nrog cov tsos mob uas yuav tiv zoo heev active tshuaj yog nonspecific mob caj dab, mob rheumatic fever, neuralgia, myalgia, arthralgia, Bechterew tus kab mob, khaub thuas, periodontitis. Lub medicament yog tseem npaj rau khob lub taub hau, mob hniav, ua npaws qaug dab peg, tej yam tshwm sim ntawm menstrual mob.

Rau "mefenamic acid" Muaj ntau ntau contraindications, lub ntsiab ntawm cov uas yog cov npau taws me ntsis xub ntiag ntawm duodenal rwj kab mob thiab lub plab, hnyuv inflammatory kab mob ntawm cov ntshav, mob raum. Thaum lub sij hawm cev xeeb tub, lactation yuav tsum yog muaj raws qhov kev siv ntawm cov tshuaj no.

Sis nrog lwm yam tshuaj nyob rau hauv pab pawg - ib tug ntau feature, uas yog yus mefenamic acid. Phau Ntawv Qhia rau cov kev npaj qhia txog nyob rau hauv kom meej tag nrho cov tau tshua thiab teeb meem. Thaum interacting nrog "Analgin" thiab salicylates enhanced anti-inflammatory nyhuv. Cov tshuaj kuj yuav tsub kom cov prothrombin lub sij hawm thaum noj anticoagulants.

Qhov loj phiv, uas muaj mefenamic acid, yog los ntawm cov hnyuv teeb meem manifested los ntawm lub cev muaj zog thiab dyspeptic teeb. Nrog heev siv cov tshuaj no tej zaum yuav tsim hemolytic anemia hom.