Khoom "Lamivudine": cov lus qhia rau kev siv, hauj lwm, muaj pes tsawg leeg thiab xyuas

Niaj hnub no, ntau thiab ntau cov neeg hnov qhov txaus ntshai mob - HIV. Qhov no pathology tau ua heev heev nyob rau hauv lub dhau los lawm ob peb decades. Antiretroviral txoj kev kho yog ib tug yuavtsum tau kawm uantej rau txuas rau lub neej ntawm cov neeg mob no. "Lamivudine" cov lus qhia rau kev siv ntawm cov uas yuav tsum tau tham nyob rau hauv kom meej hauv qab no, yog ib tug ntawm cov tshuaj uas yog siv nyob rau hauv cov kev kho mob ntawm tus kab mob HIV ke.

General kev piav qhia thiab muaj pes tsawg leeg

Nthuav yog ib qho antiviral tshuaj thiab yog siv nyob rau hauv cov kev kho mob ntawm tus kab mob HIV. Nyob rau hauv feem ntau tus neeg mob, cov tshuaj no yog siv nyob rau hauv daim ntawv ntawm ib tug dawb cov ntsiav tshuaj. Qhov tseem ceeb tshaj feem ntawm cov neeg uas sawv cev lamivudine. Ib tug ntsiav tshuaj nws muaj 100 los yog 300 mg. Ntawm cov kab Cheebtsam yuav tsum tau qhia yog: sodium cov hmoov txhuv nplej glycolate, magnesium stearate, titanium dioxide, hypromellose, polyethylene glycol.

Cov ntsiav tshuaj nyob rau hauv lub plhaub. Drug muag nyob rau hauv packs ntawm 10, 30 los yog 60 ntsiav tshuaj.

Tsis tas li ntawd, lub medicament yog manufactured li qhov ncauj tov.

pharmacological los

Yog hais tias koj xav tau ib tug "Lamivudine", cov lus qhia rau kev siv (piav qhia koj twb xam tau tias yog) qhia tau hais tias nws txiav txim: lub ntsiab yam khoom uas sai penetrates los ntawm daim nyias nyias mus rau hauv lub cell thiab metabolized. Cov tshuaj tiv thaiv tshwm transkripazy HIV inhibitor, uas cheeb qhov uas cov kev ua lej khu ntawm cov teeb meem hlwb. Cov tshuaj zoo nkaus li rau lub siab ua si ntawm lub lim uas yog tsis raug mus rau lwm yam tshuaj.

Tsis tas li ntawd txhais tau tias manifest siab kev ua si mus tus kab mob siab B. Uas yog, nws yuav muaj mus rau hauv ib tug complex txoj kev kho ntawm lub siab pathologies. Txawm li cas los, nws yuav tsum tau noj tsuas muaj ib tus kws kho mob tso cai.

Raws li cov yam khoom uas yog muab hais lus, nws cov haum tshwm sim nyob rau hauv lub hnyuv ib ntsuj av. Ntxiv mus bioavailability theem nce mus txog 86%. Yog hais tias koj noj cov ntsiav tshuaj nrog cov zaub mov, nco ntsoov tias nyob rau hauv cov ntaub ntawv no, lub sij hawm mus cuag lub siab tshaj plaws nyob rau hauv concentration cov ntshav ntshav ntawm cov nyiaj nce.

Nws mus nrog cov zis nyob rau hauv unchanged daim ntawv. Lub ntsiab tivthaiv tej zaum cov txeem mus rau hauv niam cov kua mis. Nws yog ib advisable yuav tsum txhob muab pub niam mis thaum lub sij hawm kev kho mob. Lub ib nrab neej ntawm cov tshuaj yog 3-5 teev.

Indications thiab contraindications

Yog hais tias koj xav mus yuav cov "Lamivudine» (Lamivudinum), kev siv ntawm cov tshuaj yeeb dej caw yog tau nyob rau hauv xws li mob:

1. Thaum lub sij hawm kev kho mob ntawm tus kab mob HIV nyob rau hauv cov me nyuam thiab cov neeg laus.

2. Viral Kab mob siab B (mob daim ntawv no).

Txawm li cas los, tsis yog txhua tus yog tau tso cai rau noj tshuaj no. Yog hais tias koj muab "Lamivudine" phau ntawv qhia ceeb toom ntawm lub nram qab no contraindications:

• Kuj mus rau yeeb tshuaj.

• Tsis zom cov zaub mov ntawm lactose.

• Cov me nyuam uas muaj hnub nyoog los yog lub teeb yuag lub cev. Tsis txhob muab cov tshuaj ib tug me nyuam mus txog rau 3 xyoo, raws li zoo raws li cov neeg neeg uas nws hnyav tsis tau mus txog 14 kg.

• Muaj teeb meem nrog rau cov kev huv huv ntawm lub raum muaj nuj nqi (tsawg tshaj li 30 ml / min creatinine clearance).

• sij hawm ntawm hnub thiab me nyuam mos liab noj.

Nws yuav tsum tau ceev faj nrog rau kev siv cov tshuaj nyob rau hauv cov neeg mob:

• Ib tug neeg uas paub hais tias nrog ib tug loj lub raum tsis ua hauj lwm.

• neuropathy (peripheral) nyob rau hauv ib tug mob daim ntawv los yog keeb kwm.

• pancreatitis.

Nta ntau npaum, tshwj xeeb cov lus qhia, thiab yeeb tshuaj sib tshuam

Muab "Lamivudine" (cov lus qhia rau kev siv ntawm cov tshuaj no yog txuas mus rau txhua pob) no tsuas yog ib tus kws kho mob uas muaj kev nyob rau hauv cov kev kho mob ntawm tus kab mob HIV. Khoom noj khoom haus kom tsawg tsis cuam tshuam rau kev txiav txim ntawm cov tshuaj. Qhia cov ntsiav tshuaj rau qhov yog tsis tsim nyog. Nws yog zoo dua yuav nqos nws tag nrho, tab sis nyob rau hauv cov ntaub ntawv no, lub siab tshaj plaws nyhuv yuav ua tau tiav.

Yog hais tias nws yog tsim nyog los noj cov tshuaj "Lamivudine" phau ntawv qhia muab tej kev siv: cov me nyuam tom qab peb xyoos thiab laus uas ntau tshaj 30 kg, qhov yuav tsum tau haus 1 ntsiav tshuaj (150 g), 2 lub sij hawm ib hnub twg, los yog 1 capsule (300 mg), 1 ib hnub twg. Cov me nyuam muaj 2 mus rau 12 xyoo muab 3 mg / kg lub cev hnyav ib hnub ib zaug. Nws yog qhov zoo tshaj plaws los mloog mus rau lub teeb tus kws kho mob. Lub tshwj xeeb yuav xaiv tus feem ntau pom ntau npaum raws li koj tsom, lub xeev ntawm kev noj qab nyob thiab tus kab mob heev.

Raws li rau kev koom tes, peb yuav hais rau nram qab no. Piv txwv li, thaum pa roj carbon monoxide-xeem nrog "zidovudine" ntev ntawm lub xeem kauj ruam yog nce. Tab sis "AZT" tsis muaj feem xyuam rau tus nqi ntawm feem "Lamivudine". Tsis txhob noj cov tshuaj yeeb dej caw nyob rau hauv ua ke nrog nrog "zalcitabine" "ddI" thiab sulfonamides ntawm qhov raug mob ntawm cov pancreatitis.

phiv

Txawm li cas los zoo yog "Lamivudine", cov lus qhia rau kev siv (tus nqi ntawm cov tshuaj yog 4,000 rubles ib pob, thiab ntau dua.) Hais lus txog tej tau sab los:

1. Kis kab ua pa kab mob.

2. Ib tug high degree ntawm qaug zog.

3. Mob nyob rau hauv lub taub hau.

4. Xeev siab, ntuav, raws plab.

5. Ua lub concentration ntawm hepatic enzymes.

6. tsis qab los noj mov.

Ntawm nws tus kheej nqa tawm cov tshuaj hloov yog tsis yooj yim sua. Muaj yog ib tug tej yam regimen, uas yuav tsum tsis txhob ua txhaum.

Analogs, xyuas, nta cia khoom

Yog hais tias rau ib co yog vim li cas cov tshuaj tsis haum koj, koj siv tau cov analogues piav saum toj no. muaj nyob rau hauv lawv, "Amiviren", "Virola," "Zeffiks", "Epivir." Lawv muaj xws li cov teebmeem.

Txee-lub neej ntawm cov tshuaj yog 3 lub xyoo. Khaws cov cuab yeej koj yuav tau nyob rau hauv ib qho chaw muaj kev tiv thaiv los ntawm lub ingress ntawm lub teeb rays. Tom ntej no yuav tsum tsis txhob ua cua sov kiag li lawm. Tsis tas li ntawd, nws yog ntshaw kom tshem tawm cov tshuaj los ntawm lub chav tsev nyob qhov twg muaj ib theem siab ntawm av noo.

Raws li rau lub xyuas, lawv yog cov sib txawv. Nyob rau hauv ib tes, cov neeg mob qhia zoo hauj lwm zoo ntawm cov tshuaj nyob rau hauv sib ntaus tawm tsam tus kab mob HIV. Nyob rau lwm cov tes, lawv tham txog lub siab uas yuav muaj kev phiv. Feem ntau cov feem ntau cov tshuaj provokes ntuav, mob qaug zog. Raws li sawv cev los ntawm txhais tau tias ua ke nrog rau lwm cov antiviral agents, cov kev siv ntawm pliaj tshua yuav ua. Yog li ntawd kho yeeb tshuaj, raws li zoo raws li tau kho nws ntau npaum no yuav tsum tau tus kws kho mob.

Tam sim no koj muaj tag nrho cov lus qhia txog cov tshuaj "Lamivudine". Cov lus qhia rau kev siv, nqe, xyuas yog tam sim no lub npe hu rau koj. Nyob twj ywm noj qab nyob zoo!