"Kaffetin Khaub thuas": cov lus qhia rau kev siv, muaj pes tsawg leeg, analogues

Yuav ua li cas yog tus kho "Kaffetin Khaub thuas"? Muaj pes tsawg leeg thiab cov yam ntxwv ntawm cov tshuaj yuav tsum tau muab los sib tham li hauv qab no. Peb kuj qhia koj txog yuav ua li cas tau txais hais tias medicament thiab nyob li cas cov kab mob nws yog tshuaj.

Tus duab, ntim, muaj pes tsawg leeg

Lub medicament "Kaffetin Khaub thuas" yog marketed nyob rau hauv cov ntsiav tshuaj daim ntawv thiab ib tug biconvex oblong zoo (ib tug kab nyob rau ib sab) coated xiav zaj duab xis-coated. Lawv muab tso rau hauv ib lub perforated sawv hlwv, muaj raws ntawm txhuas ntawv ci thiab ib tug peb-txheej tshab zaj duab xis, uas yog nyob rau hauv ib tug thawv thawv.

Uas muaj ib tug yeeb tshuaj raws li "Kaffetin Khaub thuas"? Muaj pes tsawg leeg ntawm no yeeb tshuaj yog:

• dextromethorphan hydrobromide (15 mg);
• pseudoephedrine hydrochloride (30 mg);
• ascorbic acid (60-62 mg) raws li ib tug granulate, uas muaj 97% ntawm vitamin C, thiab 3% hydroxypropyl methylcellulose;
• paracetamol (500-555 mg) nyob rau hauv daim ntawv ntawm granules muaj 90% ntawm cov tshuaj yeeb dej caw, raws li zoo raws li koom haum pab Cheebtsam li prozhelatinizirovanogo starch, stearic acid thiab povidone.

Nws yuav tsum tau muab sau tseg tias "Kaffetin Khaub thuas" raws li ntxiv cov khoom xyaw muaj xws li magnesium stearate, silica colloid, microcellulose, croscarmellose sodium thiab talc.

Zaj duab xis txheej ntawm lub medicament yog ua los ntawm cov kob xiav zas, macrogol, titanium dioxide, polyvinyl cawv thiab talc.

Lub pharmacology ntawm cov tshuaj

Yuav ua li cas cov khoom yog cov yam ntxwv ntawm cov ntsiav tshuaj 'Kaffetin Khaub thuas "? Instruction hais tias lub cuab tam yog tau qhia analgesic thiab antitussive zog.

Lub mechanism ntawm qhov kev txiav txim ntawm lub medicament vim muaj cov nyob rau ntawd cov saum toj no Cheebtsam. Xav txog lawv nta tam sim no:

• Paracetamol muaj feem xyuam rau lub cev thiab obezbolivayusche zharoponizhayusche. Qhov no lub caij yog muaj peev xwm mus thaiv COX nyob rau hauv lub Cns. Qhov no tshwm sim los ntawm ncaj qha los ntawm cov mob chaw zov me nyuam thiab thermoregulation.

Lub qhov txawv feature ntawm no muaj ntawm narcotics yuav muab yog tag nrho tsis muaj anti-inflammatory nyhuv. Paracetamol tsis thab plaub hauv lub digestive ib ntsuj av tau thiab tsis cuam tshuam rau cov dej-ntsev metabolism, raws li nws tsis cuam tshuam rau lub synthesis ntawm prostaglandins nyob rau hauv peripheral ntaub so ntswg.

• Yuav ua li cas lwm tus neeg yog zoo kawg li tshuaj "Kaffetin Khaub thuas"? Extraction pseudoephedrine yog tau muab ib tug tapered tej yam nyob rau hauv cov hlab ntsha uas yog nyob rau hauv lub mucosa ntawm lub caj pas thiab qhov ntswg kab noj hniav. Tsis tas li ntawd, qhov no caij zoo heev thiaj o, li no kom txhob muaj pa nyob rau hauv lub nasopharynx thiab yooj yim qhov ntswg ua tsis taus pa.
• Ascorbic acid yog muaj nyob rau hauv lub tsheb, rov qab ntawm vitamin C tsis muaj peev xwm, uas yog feem ntau pom thaum lub sij hawm mob khaub thuas.
• Dextromethorphan muaj feem xyuam rau cov hnoos chaw. Nws thiaj li heev ntawm lub qhuav hnoos uas yog txuam nrog voos ntawm cov qog ua kua nasopharynx rau mob khaub thuas.

kev tig tau zog

Yuav ua li cas puas muaj tus haum ntawm cov tshuaj "Kaffetin Khaub thuas"? Xyuas tshwj xeeb qhia tau tias tus haum ntawm feem ntau ntawm cov paracetamol tshwm sim nyob rau hauv cov hnyuv. Yog li nws siab tshaj plaws nyob rau hauv concentration cov ntshav ntshav yog cai tsis pub dhau 30-90 feeb tom qab qhov ncauj thawj coj.

Cov metabolism ntawm cov tshuaj yeeb dej caw nyob rau hauv lo lus nug (txog 90-95%) tshwm sim nyob rau hauv lub siab. Raws li ib tug tshwm sim, tsaug zog derivatives raug tsim (vim lub conjugation tshuaj tiv thaiv uas glucuronic acid thiab sulfates). Lawv yuav muaj ib tug thaiv cov hlab cov nyhuv ntawm cov enzyme system ntawm lub siab, raws li tau zoo raws li rau ntxias txoj kev tuag ntawm lub hlwb.

Lub ib nrab-lub neej ntawm cov tivthaiv los ntawm tib neeg yog 1-4 teev. Tso tawm kom pom paracetamol thiab nws cov metabolites los ntawm ob lub raum. Nyob rau hauv cov laus hnub nyoog tej zaum yuav ib tug txo nyob rau hauv clearance ntawm cov tshuaj, raws li zoo raws li ib qho kev nce rau hauv ib nrab-lub neej lub sij hawm.

Tom qab dextromethorphan tau txais mus rau hauv tib neeg lub cev, nws yuav luag tam sim ntawd absorbed rau hauv cov hlab ntsha. Qhov siab tshaj plaws concentration ntawm no nyob rau hauv cov ntshav yog cai tom qab 130 feeb tom qab noj cov ntsiav tshuaj. Qhov no tshuaj yog metabolized nyob rau hauv lub siab. Nws metabolites yog tas nyob hauv cov zis.

Pseudoephedrine kuj sai absorbed rau hauv lub mauj kev tom qab qhov ncauj thawj coj. Qhov siab tshaj plaws concentration ntawm cov tshuaj yeeb dej caw yog tiav tom qab txog 2 teev ib ntshav. Ib nrab-lub neej ntawm pseudoephedrine yog hais txog 6 sij hawm. Nws yog metabolized nyob rau hauv lub siab (ib feem), li no txoj kev derivative uas tom qab tas nyob hauv cov zis.

Raws li rau lub ascorbic acid, nws yog zoo yaim los ntawm tus mob huam thiab sai heev faib rau txhua tus ntaub so ntswg. Qhov no feem yog reversibly oxidized rau degidroksiaskorbinovoy acid. Nyob rau hauv cov ntaub ntawv no ib co ntawm cov vitamin C tau txais los ntawm lub cev, metabolized nyob rau hauv lub caij hu ua ascorbate-2-sulfate.

Tas cov tshuaj yeeb dej caw zoo nkaus li nyob rau hauv cov zis.

zaj lus tim khawv

Tshuaj "Kaffetin Khaub thuas" yog siv rau cov symptomatic kev kho mob ntawm kev mob ua npaws thiab mob khaub thuas, xws li qhov tshwm sim ntawm tej tsis kaj siab tsos mob, xws li mob taub hau, hnoos qhuav, mob leeg, mob nyob rau hauv lub caj pas, los ntswg qhov ntswg, kub taub hau, qhov ntswg thiab qhov ntswg sinuses .

Contraindications

Tshuaj "Kaffetin Khaub thuas" yuav siv tsis tau nyob rau hauv cov neeg mob uas cov nram qab no tej yam kev mob:

• cev xeeb tub;
• Npau taws me ntsis mus rau yeeb tshuaj;
• congenital tsis muaj glucose-6-phosphate dehydrogenase;
• tawg, coronary mob plawv, angina pectoris;
• mob loj heev mob nyob rau hauv lub raum thiab lub siab, kab mob siab;
• simultaneous txais tos ntawm antidepressants, monoamine oxidase inhibitors thiab cov tshuaj uas yog siv nyob rau hauv cov kev kho mob ntawm antiparkinsonian;
• lactation;
• muaj hnub nyoog 12 xyoo.

Cov kev ceev faj yog ib yam tshuaj pom zoo rau:

• arrhythmia;
• benign hyperbilirubinemia;
• hyperthyroidism;
• kab kab mob siab;
• hyperplasia ntawm lub prostate caj pas;
• alcoholism;
• mob ntshav qab zib mellitus;
• obstructive koj muaj teebmeem kev kab mob mob qhov;
• bronchial hawb pob;
• qaug.

Medicament "Kaffetin Khaub thuas": cov lus qhia rau kev siv

Xam tias yog tsuas txhais tau hais tias npaj rau qhov ncauj thawj coj.

Ntau npaum rau cov neeg laus thiab cov me nyuam hluas los ntawm 12 xyoo ntawm lub hnub nyoog yog 1 ntsiav tshuaj plaub zaug ib hnub twg. Nyob rau ib lub sij hawm yog tau tso cai rau siv tsis muaj ntau tshaj li 2 ntsiav tshuaj.

Lub sij hawm caij nyoog nruab nrab siv cov tshuaj yuav tsum tsis txhob yuav tsawg tshaj li 4 teev. Yog li lub hnub ntau npaum ntawm cov tshuaj yuav tsum tsis txhob ntau tshaj 8 ntsiav tshuaj.

Yog hais tias muaj tsis kub taub hau rau ntau tshaj 3 hnub tom qab pib ntawm txoj kev kho, thiab ib tug hnoos qhuav tsawv rau 5 hnub, ces koj yuav tsum tam sim ntawd nrhiav kev pab kho mob.

phenomena sab

Phiv tshua tom qab noj cov tshuaj nyob rau hauv kev saib xyuas tej zaum yuav manifested nyob rau hauv ntau txoj kev, los ntawm yuav luag tag nrho cov nruab nrog cev thiab tshuab ntawm lub cev:

• xeev siab, qhov ncauj qhuav, epigastric mob;
• somnolence, ntxhov siab, txob taus, kiv taub hau;
• kev tsis haum tshuaj raws li pruritus, daim tawv nqaij ua pob ua xyua, angioedema, urticaria;
• nce ntshav siab, tachycardia txoj kev loj hlob;
• anemia, thrombocytopenia, agranulocytosis, pancytopenia;
• nephrotoxic nyhuv, uas yog manifested raum Colic, txoj kev loj hlob ntawm papillary necrosis los yog interstitial nephritis.

Ib tug overdose ntawm cov tshuaj

Thaum dua koob tshuaj yeeb tshuaj, tus neeg mob tej zaum yuav muaj kev xeev siab, tinnitus thiab mob nyob rau hauv lub plab cheeb tsam. Tsis tas li ntawd nrog tshaj tshuaj noj tshuaj npaum cas tus neeg mob daim tawv nqaij yuav daj ntseg, nws nce thiab hws yuav nquag palpitations.

Piav yuav tsum tau tam sim ntawd yaug kais dej plab. Tsis tas li ntawd, lub koob tshuaj muab rau tus neeg mob txais carbon, cov neeg mob hnyav. Yog hais tias yuav tsum tau, lub symptomatic txoj kev kho.

sis

Paracetamol nyob rau hauv siab koob tshuaj tsub kom cov teebmeem ntawm anticoagulants.

Siv cov tshuaj uas yog inducers ntawm microsomal oxidation (e.g., "Phenytoin", ethanol, barbiturates, "Rifampicin", "phenylbutazone", tricyclic antidepressants), thiab hepatotoxic agents ho tsub kom lub tsim ntawm active hydroxylated metabolic khoom ntawm paracetamol, uas tsub kom qhov yuav mob intoxication Development , nrog rau cov kev txais tos ntawm me me koob tshuaj ntawm cov tshuaj.

Heev siv cov barbiturates thiaj li efficiency ntawm paracetamol.

Lub ua ke ntawm paracetamol thiab salicylates kom kev pheej hmoo ntawm mob cancer ntawm lub zais zis los yog ob lub raum.

Heev siv cov NSAID thiab paracetamol txhawb tshwm sim analgesic nephropathy, raum papillary necrosis thiab ho los ze zog end-stage raum tsis ua hauj lwm.

Siv "diflunisal" ua rau cov hepatotoxic nyhuv ntawm cov tshuaj.

Tib siv pseudoephedrine thiab lwm yam sympathomimetic cov neeg ua hauj tej zaum yuav ua rau kom qhov tshwm sim ntawm tshuaj lom los, thiab muaj ib tug additive nyhuv. Lub ua ke ntawm no tivthaiv nrog ib tug monoamine oxidase inhibitors feem ntau ua rau cov kev loj hlob ntawm hypertensive ntsoog. Nyob rau hauv no hais txog, cov kev siv ntawm cov tshuaj nyob rau hauv kev saib xyuas muaj cai tsis muaj ntxov tshaj 14 hnub tom qab tau txais monoamine oxidase inhibitors tau haujlwm.

Tib siv ntawm "Propranolol" tej lub pressor nyhuv uas yog pseudoephedrine. Tsis tas li ntawd, thaum uas siv cov tom kawg yuav raug muab txo hypotensive nyhuv ntawm cov cuab yeej xws li "methyldopa", "reserpine", "mecamylamine" thiab t. N.

Cov ntaub ntawv

Tam sim no koj paub tias qhov no yog ib tug yeeb tshuaj raws li "Kaffetin Khaub thuas."

Methamphetamine - yog methamphetamine. Nws yog ib hom thiab ua siab nyob tos nyob rau hauv kev twb kev txuas nrog dab tsi yog hais txog cov tshuaj. Ib txhia neeg tseem tabtom coj no feem ntawm cov tshuaj "Kaffetin Khaub thuas." Yov ntawm cov tshuaj nyob rau hauv ntau txoj kev. Nws txais tos ua kev zoo siab thiab yog li adversely muaj feem xyuam rau tag nrho cov tshuab thiab kabmob.

Thaum lub sij hawm kev kho mob, ib tug yeeb tshuaj yuav tsum muab suav hais tias tsim nyog los saib xyuas tej lub xeev ntawm tus neeg mob lub siab, raws li zoo li ntsuas ntawm peripheral cov ntshav.

Thoob plaws hauv cov kev kho mob rau tus neeg mob yog txwv tsis pub haus dej haus cawv, li no yuav ua rau hepatotoxicity kev txiav txim ntawm cov tshuaj. Cov tib mus rau caffeine cov cuab yeej thiab cov khoom.

Saib cov tshuaj muaj ib tug ncaj qha feem rau tus neeg mob tus muaj peev xwm tsav tsheb thiab koom nyob rau hauv tej lwm yam uas yuav tsum tau siab concentration ntawm cov xim.

Tshuaj "Kaffetin Khaub thuas": tawm los ntawm cov chaw muag tshuaj

Vim lub fact tias cov tshuaj no yog feem ntau siv raws li ib tug yeeb tshuaj, nws yog tso tawm tsuas yog thaum kev nthuav qhia ntawm ib tug kws kho mob tshuaj. Los ntawm txoj kev, mus nrhiav tau xws li ib tug yeeb tshuaj nyob rau hauv pharmacies yog heev yooj yim. Feem ntau nws yog tauj tom qab lub pre-order.

zoo xws li cov tshuaj

Muaj ntau ntau txhais tau tias los ntawm uas cov tshuaj nyob rau hauv lo lus nug tau muab hloov. Cov feem nrov xws li cov nram qab no: "Amitsitron Forte", "Antigrippin", "Bol-Khiav hwm", "Vokasept", "Gripgo", "Gripkold-N", "Gripotsitron Forte", "Gripflyu", "Dolar", " Khaub thuas H "," Koldreks "," Koldfri "," Lemsip Txiv qaub "," Novalgin "" Panadol Ntxiv "," Rinzai "," Tamipul "," Farmatsitron "thiab lwm tus neeg.