Tshuaj thiab bodybuilding. kom androstenedione

Androstenedione hais txog rau cov txiv neej nrog txiv neej pw lawm. Qhov no androgen yog testosterone precursor. Nyob rau hauv cov txiv neej, uas nws ntau lawm yuav siv sij hawm qhov chaw tsuas yog nyob rau noob qes. Nyob rau hauv cov poj niam, 60% ntawm cov androstenedione yog lub txiaj ntsim ntawm peripheral hloov, 40% yog ua nyob rau hauv lub adrenal qog thiab zes qe menyuam. Thaum lub fairer nrog txiv neej pw npaum li cas ntawm tsim thiab secretion ntawm no lawm yog siab tshaj testosterone, thiab tshuam ntev qhia extraadrenal nws hloov dua siab tshiab rau testosterone.

androstenedione theem yog txiav txim nyob rau hauv ib tug complex DHEA-S thiab DHEA. Qhov no yog tsim nyog rau diagnostic hom phiaj thiab ntsuam xyuas cov kho nyhuv nyob rau hauv lub hyperandrogenic tej yam kev mob.

Kom androstenedione nyob rau hauv lub tsom xam ntawm cov ntshav yog yam ntxwv ntawm cov neeg mob nrog adrenal cortex hyperplasia congenital xwm. Tsis tas li ntawd, thaum muaj feem kuaj syndrome Cushing, hyperplasia los yog neoplasm testicular stroma nyob rau hauv lub zes qe menyuam, raws li tau zoo raws li ectopic ACTH secretion.

Tsa androstenedione pom nyob rau hauv cov neeg mob uas hirsutism thiab polycystic zes qe menyuam.

Nyob rau hauv kev kho mob xyaum, lub ntshiab ntau ntawm cov hormone yog dav siv rau saib xyuas cov hauj lwm zoo ntawm tshuaj tiv thaiv uas siv cov glucocorticoids nyob rau hauv congenital adrenal hyperplasia, raws li nws yog suav tias yog lub feem ntau muaj tseeb kev ntsuas dua li lwm cov androgens.

Tsis muaj zog androstenedione, thiab vice versa, txo nws cov ntsiab lus qhia rau hauv lub xub ntiag ntawm sickle-cell anemia. Pathology npaj tawm tsam lub backdrop ntawm zes qe menyuam thiab adrenal insufficiency.

Androstenedione. Thaum kuaj?

Indications rau txoj kev tshawb no yog:

- xyuas kev kho mob thiab kuaj mob ntawm hyperandrogenic tej yam kev mob;

- me nyuam mob nyob rau hauv lub keeb kwm yav dhau ntawm hormonal tsis ua hauj lwm;

- kev kho mob nrog glucocorticoids.

Kev mloog yog them androstenedione neeg muab kev koom tes nyob rau hauv kev bodybuilding. Nws yog ntseeg hais tias cov tshuaj preparations, thiab nws txheem txhawb leeg txoj kev loj hlob. Txawm li cas los, qhov no yog tsis ib txwm rooj plaub.

Androstenedione yog lub ntsiab lawm ntawm cov qog adrenal thiab yuav hloov dua siab tshiab los yog testosterone los yog cov tshuaj no. Nyob rau hauv thawj rooj plaub no nws yog tsa los ntawm kev enzyme hloov dua siab tshiab. Nws yuav tsum tau muab sau tseg tias cov saw ntawm transformations ntawm steroid androstenedione rau testosterone yog closer tshaj DHEA. Qhov no ua rau ib tug ntau dua nws lub peev xwm los hloov. Yog li, lub resultant hloov dua siab tshiab ntawm androstenedione rau testosterone tom qab nyob rau hauv tus ntawm lwm enzyme yuav mus rau hauv dihydrotestosterone. Qhov no, nyob rau hauv lem, muaj txhawb rau txoj kev loj hlob ntawm ntau unpleasant txim. Dihydrotestosterone nkoos thiab balding lub taub hau, thiab o ntawm lub prostate, raws li zoo raws li ntev li plaub hau kev loj hlob ntawm lub cev thiab lub ntsej muag. Nyob rau hauv tas li ntawd, anabolic zog nws tsis muaj, txawm li cas los twb tsis muaj ntxim rau cov mob pawg. Yog li, thaum androstenedione ntau zog, muaj yog tau ua tsi ntsees ntawm dihydrotestosterone.

Nyob rau hauv tas li ntawd mus rau cov teebmeem, muaj lwm yam tab kaum - gynecomastia. Nkoos txoj kev loj hlob ntawm lub mis hloov dua siab tshiab ntawm testosterone rau estradiol (aromatization).

Dua li ntawm qhov tseeb ntawm advertisers uas nce androstenedione zoo heev ntxim rau cov mob loj yog tias coj kom raug, hormonal "manipulation" yog feem ntau unpredictable thiab yooj yim txheej txheem. Tseem xav qhov tseeb hais tias qhov kev nce nyob rau hauv testosterone ntau ntau siv hormonal tshuaj, ntawm chav kawm, muaj feem xyuam rau lub system uas tswj zus tau tej cov txiv neej pw steroids.

Niaj hnub no, androstenedione thiab nws cov nyhuv rau tib neeg zoo to taub. Tsis tas li ntawd, thaum tau txais cov los yog lwm yam hormonal npaj yuav tsum coj mus rau hauv tus account cov yam ntxwv ntawm txhua kab. Piv txwv li, nyob rau hauv ib co nce nyob rau hauv lub concentration ntawm androstenedione nyhuv lig rau mob loj, thaum lwm tus neeg tau teeb meem loj.