Lipid tej tshuaj "Rosuvastatin": cov lus qhia rau kev siv

Tshuaj "Rosuvastatin" phau ntawv qhia no qhia txog li hypolipidemic tshuaj ntawm statins. Lub lag luam ntawm no xim txhais tau tias yog kev sib tw inhibition ntawm HMG-CoA reductase. Cov kev siv ntawm ib tug kev npaj "Rosuvastatin" (cov lus qhia rau kev siv nws qhia) ob peb lub sij hawm ntau zog LDL catabolism, nce tus nqi ntawm hepatic LDL receptors thiab tus nqi ntawm VLDL txo. Raws li hais tus pharmacokinetic thaj chaw ntawm lub lipid tej tshuaj, cov lus hais kho nyhuv ntawm nws txais tos cai xya hnub tom qab pib ntawm txoj kev kho, kho kom sawvdaws xeeb nws zoo tshaj plaws tshwm sim nyob rau hauv plaub lub lis piam.

Siv cov ntsiav tshuaj "Rosuvastatin" chaw tsim tshuaj paus xav hais tias cov neeg txom nyem los ntawm cov mixed daim ntawv ntawm hypercholesterolemia (ntaus IIb) hypercholesterolaemia los yog IIa (xws li heterozygous) raws li ib tug adjunct mus noj cov zaub mov.

Yog li lub siab tshaj plaws efficiency hypolipidemic active tshuaj yog nyob rau hauv lub rooj plaub thaum lwm cov kev kho txoj kev (cev qoj ib ce, yuav txo tau ntawm lub cev hnyav) tsis ua rau lub attainment ntawm ib tug kom kho tshwm sim. Tsis tas li ntawd, siv xim neeg sawv cev "Rosuvastatin" phau ntawv qhia kom raws li ib tug pab tshuaj thaum lub sij hawm txoj kev kho homozygous hypercholesterolemia tsev neeg hom.

Muab cov ntsiav tshuaj yog nruj me ntsis txwv tsis pub nyob rau hauv cov ntaub ntawv ntawm ib tug neeg mob mob siab cov kab mob, myopathy los yog mob qhia nyob rau hauv lub raum. Thaum lub sij hawm cev xeeb tub, kuj yuav tsum tsis txhob coj lipid tej tshuaj "Rosuvastatin." Cov tshuaj yog ua rau lub lactation lub sij hawm. Tsis tas li ntawd, nws yog tsis pom zoo kom noj cov ntsiav tshuaj thaum tib lub sijhawm nrog cyclosporine los yog npau taws me ntsis rau lawv lub Cheebtsam. Cov neeg uas tsis tau ua li cov muaj hnub nyoog ntawm kaum yim, thiab nws tsis yog tsim nyog los xaiv ib tug neeg sawv cev xim "Rosuvastatin." Cov lus qhia rau kev siv yog tsis kom koj noj nws nyob rau hauv cov ntaub ntawv ntawm haus dej caw dependence tsim lub raum tsis ua hauj lwm los yog siab mob.

Nrog zoo saib xyuas yuav siv cov lipid tej tshuaj yuav tsum yog tus neeg txom nyem ntsha, endocrine thiab metabolic mob, hypothyroidism los yog hypotension. Nyob rau hauv sepsis, uncontrolled, qaug dabpeg, proteinuria, loj poob plig thiab phais tiv thaiv kuj yuav tsum tsis txhob noj cov tshuaj, "Rosuvastatin." Nyob rau hauv tas li ntawd, tus kwv tij contraindications yog raws roj ntsha npag cov kab mob thiab muaj hnub nyoog laus dua tshaj li rau caum-tsib xyoo.

Nyob rau hauv xaus, nws yuav tsum tau hais tias hais txog cov tau phiv tshuaj, qhov tshwm sim ntawm uas yuav tau triggered thaum uas tus txais tos txhais tau tias "Rosuvastatin." Piv txwv li, muaj ntau cov neeg mob tsis txaus siab ntawm plab, quav tawv, kiv taub hau thiab xeev siab. Nyob rau hauv tas li ntawd, muaj me ntsis kev pheej hmoo ntawm myopathy, proteinuria, asthenia , thiab myalgia.