Cov tshuaj "Gynestril": cov lus qhia rau kev siv, analogs thiab xyuas

Yuav ua li cas mus noj cov tshuaj "Gynestril"? Cov lus qhia rau kev siv tshuaj no yuav tsum tau piav nyob rau hauv cov ntaub ntawv ntawm qhov tsab xov xwm. Nyob rau hauv nws, peb muaj cov lus teb ntawm cov neeg mob, cov tshuaj, nws pharmacological yam ntxwv, indications thiab contraindications.

Muaj pes tsawg leeg, zoo

Yuav ua li cas Cheebtsam muaj xws li tshuaj "Gynestril"? Cov kev cai annexed rau qhov no txhais tau tias, nws yog hais tias nws cov active ingredient yog mifepristone. Tsis tas li ntawd lub medicament muaj ntxiv cov khoom xyaw rau hauv daim ntawv ntawm qos starch, lactose, microcrystalline cellulose, povidone, magnesium stearate thiab sodium carboxymethyl cov hmoov txhuv nplej.

Yuav cov tshuaj no yuav ua tau nyob rau hauv cov ntsiav tshuaj, uas yog fej nyob rau hauv packs ntawm cardboard.

Pharmacological yam ntxwv tshuaj

Koj puas paub hais tias yog ib tug yeeb tshuaj "Gynestril"? Cov lus qhia rau kev siv yuav pab tau koj to taub cov cai hais txog kev txiav txim ntawm cov tshuaj no, thiab yuav qhia rau koj tias nyob rau hauv tsis muaj indications ntawm nws siv nyob rau hauv kev kho mob xyaum.

Saib medicament yog ib tug steroid neeg sawv cev antigestagens hluavtaws keeb kwm. Tus kho miv nyuas siv zug ntawm cov tshuaj vim nws muaj pes tsawg leeg.

Thaum tau txais daim ntawv ntawm mifepristone nyob rau hauv tib neeg lub cev nws cheeb qhov uas cov teebmeem ntawm progesterone, tab sis tsis muaj progestational kev ua si.

Kws txawj nco ntsoov lub thaiv ntawm cov tshuaj vim kev sib tw nrog glucocorticoid losis tswvyim dabtsi nyob rau receptor theem.

Raws li yog lub npe hu, lub ntsiab luag hauj lwm nyob rau hauv lub tsim ntawm uterine leiomyoma muab rau poj niam cov tshuaj hormones, tshwj xeeb yog progesterone. Nyob rau hauv no hais txog, mifepristone yuav raug muab tso rau ib tug neeg mob los thaiv lub progesterone receptor. Raws li ib tug tshwm sim ntawm qhov kev kho no yuav siv sij hawm qhov chaw nyob rau hauv lub pob loj hlob qeeb, raws li zoo raws li txo qhov luaj li cas ntawm fibroids , uterine thiab.

Lub pharmacokinetic thaj chaw ntawm cov tshuaj

Yuav ua li cas nta muaj pharmacokinetic tshuaj "Gynestril"? Cov lus qhia, xyuas tej kws kho mob hais tias tom qab qhov ncauj thawj coj lub siab tshaj plaws concentration ntawm cov tshuaj yog cai nyob rau hauv hais txog 80 feeb. Ntxiv mus, nws bioavailability yog 69%.

Ntshav cov nqaijrog xam tau tias yog tshuaj uake rau 98% (nrog albumin thiab alpha-1 acid glycoprotein).

Tom qab lub tsev theem no tshwm sim qeeb tshem tawm theem. Nyob rau hauv cov ntshav concentration ntawm cov tshuaj yog txo los ntawm ib nrab (nruab nrab ntawm 15 thiab 72 teev).

Ntaus ntawm cov tshuaj yog ceev ceev, nrog ib lub sij hawm ntawm 18 teev.

indications

Los ntawm uas tus tshuaj "Gynestril" yuav raug muab tso? Cov lus qhia rau kev siv, tiag tiag cov kws txawj muab cov nram qab no indications:

• kev kho mob ntawm uterine leiomyoma;
• txiav intrauterine cev xeeb tub mus rau 42 hnub;
• induction (los yog stimulation) ntawm zog (xws li thaum lub sij hawm);
• thaum muaj xwm ceev pov (postcoital) rau unreliability siv contraceptive, thiab nyob rau hauv lub sij hawm tom qab tiv thaiv kev sib deev com.

Contraindications

"Gynestril" tshuaj rau rho menyuam yuav tsum tsis txhob siv thaum:

• clinically unconfirmed cev xeeb tub;
• permissible ectopic cev xeeb tub;
• cev xeeb tub uas sawv tom qab tshem ntawm hormonal contraceptive txhais tau tias, los yog los ntawm kev siv ib tug intrauterine contraceptive;
• cev xeeb tub tom qab 42 hnub.

Thaum leiomyoma tshuaj no yog txwv tsis pub mus muab nyob rau hauv cov nram no mob:

• muab ntawm submucous myoma ntshav;
• nyob rau hauv ntawm zes qe menyuam hlav;
• endometrial hyperplasia;
• yog leiomyoma nqi yog loj.

"Gynestril" Ntsiav tshuaj rau induction ntawm zog yog tsis siv nyob rau hauv:

• mob loj heev preeclampsia;
• txawv txav me nyuam hauv plab kev nthuav qhia;
• pre-eclampsia;
• eclampsia;
• preterm los yog post-lub sij hawm cev xeeb tub;
• imbalances luaj li cas ntawm cov me nyuam hauv plab lub taub hau thiab niam lub plab mog;
• undiagnosed spotting los ntawm qhov chaw mos huam thaum lub sij hawm hnub.

Puas muaj cov kev contraindications tshuaj "Gynestril"? Cov lus qhia uas muab rau lo lus nug no yog txhua tus tib. Cov kev txwv no muaj xws li cov nram qab no tej yam kev mob:

• porphyria;
• long-term kho nrog glucocorticoids;
• muaj ntshav liab txaus;
• raum lossis daim siab tsis ua hauj lwm (nyob rau hauv tej daim ntawv no);
• ua txhaum ntawm hemostasis (yav dhau los anticoagulant kev kho mob);
• extragenital xwm;
• pathology ntawm tus poj niam lub tsev me nyuam system, uas yog ib qho inflammatory cim;
• npau taws me ntsis (xws li keeb kwm);
• nikotinozavisimost, tshwj xeeb tshaj yog tom qab lub hnub nyoog ntawm 35.

Nrog huab ceev faj thaum noj yam tshuaj no:

• obstructive koj muaj teebmeem kev kab mob (mob ua cim);
• lub plawv tsis ua hauj lwm;
• tawg;
• arrhythmia;
• bronchial hawb pob;
• lub plawv atherosclerosis teeb.

Tshuaj "Gynestril": daim ntawv qhia

Rau txiav ntawm cev xeeb tub (neeg mob xyuas ntawm no medicament yuav tsum tau tham ib tug me ntsis ntxiv), cov tshuaj no yuav tsum tau muab tsuas yog ib lub vos tshwj xeeb. Thiab kev noj cov ntsiav tshuaj nyob rau hauv cov ntaub ntawv no tau tsuas yog nyob rau hauv lub xub ntiag ntawm ib tug gynecologist.

Txij li thaum cov tshuaj siv "Gynestril"? Cov lus qhia rau cev xeeb tub txiav hais tias nws yog tsim nyog los siv ib zaug xwb koob tshuaj ntawm 600 mg.

Cov tshuaj no yog noj 1-1.5 xuab moos tom qab noj mov thiab ntxuav cia nrog 100 ml ntawm cov dej.

Yuav kom nce lub miv nyuas siv zug ntawm cov tshuaj yuav ntxiv lub hom phiaj 400 mg misoprostol (i.e., ib tug hluavtaws prostaglandin E1).

Tom qab tau txais cov ntsiav tshuaj tus neeg mob yuav tsum tau saib xyuas obstetrician tsawg kawg yog ob teev. Tom qab 1.5 hnub los yog 2 nqa ultrasound. Txawm tom qab 1-2 lub lis piam mus coj kev soj ntsuam kev soj ntsuam thiab rov ultrasound thiab saib ntshav ntawm hCG kom paub meej tias ib tug nchuav menyuam.

Nyob rau hauv cov ntaub ntawv uas, yog hais tias tus tshuaj tsis pab (ie, cev xeeb tub tseem), tus kws kho mob pom zoo kom ib lub tshuab nqus aspiration rau kawm ntxiv (histology) cov ntsiab ntawm cov txheej txheem.

Yuav kom tsim kho lub generic kev ua ub no, cov tshuaj ib zaug muab nyob rau hauv ib tug ntau npaum ntawm 200 mg. Lawv ua li no nyob rau hauv lub xub ntiag ntawm ib tug gynecologist. Tom qab ib hnub, lub koob tshuaj ntawm cov tshuaj yog rov qab nyob rau tib lub koob tshuaj.

Tom qab 2-3 hnub, kwv yees expansion ntawm cov me nyuam yug kwj dej. Yog li txiav txim tau ntxiv siv "oxytocin" los yog prostaglandins.

Raws li rau uterine leiomyoma siv yeeb tshuaj "Gynestril"? Phau Ntawv Qhia hais tias thaum xws mob kev npaj no feem ntau yog muab nyob rau hauv ib tug ib koob tshuaj ntawm 50 mg. Cov tshuaj no yuav hais rau peb lub hlis.

Nrog kev xav txog post-coital pov, cov kws kho mob pom zoo kom siv ntawm qhov suav hais tias medicament nyob rau hauv ib tug npaum li ntawm 10 mg rau peb hnub tom qab tiv thaiv kev sib deev com (tsis hais txog ntawm cev theem). Noj tshuaj nyob rau hauv cov ntaub ntawv no nws yog ntshaw rau ob teev ua ntej los yog tom qab noj mov.

tus neeg mob ntawm overdose

Siv ntawm cov tshuaj nyob rau hauv ib koob tshuaj tsis muaj ntau tshaj li ob grams ntawm ua tej yam uas tsis zoo los. Thaum uas siv cov ntau tshaj qhov teev tus nqi ntawm cov tshuaj ib tug neeg mob tej zaum yuav tsim adrenal insufficiency, uas yuav tsum tau symptomatic txoj kev kho.

phiv

Tau txais medicament "Gynestril" feem ntau ua rau tej tshwm sim raws li mob taub hau, xeev siab, kiv taub hau, ntuav, ua pob liab vog, raws plab, amenorrhea, lohiometra spotting, uterine subinvoljutcija, hyperthermia, emmeniopathy, tsis muaj zog, kev nyuaj siab mob ntawm lub tsev me nyuam thiab appendages, tsis xis nyob thiab mob nyob rau hauv lub plab mog. Yog hais tias koj muaj kev cov tsos mob no, nco ntsoov sab laj ib tug kws kho mob.

tshuaj cov kev sib tshuam

Nws tsis pom zoo kom noj cov tshuaj "Gynestril" nyob rau hauv thaum uas tig mus nrog narcotics yuav muab. Nws yuav tsum tau muab sau tseg tias nyob rau hauv ua ke nrog nrog glucocorticoids yog tsim nyog los ua rau kom cov tshuaj, tab sis tsuas yog tom qab kev noj kev haus koj tus kws kho mob.

tej tswv yim pom zoo

Nws tsis pom zoo kom noj cov tshuaj raws li ib tug tsis tu ncua contraceptive.

Thaum koj siv tus "Gynestril" rho menyuam yuav tsum nco ntsoov qhia rau tus neeg mob txog lwm cov kev xaiv ntawm txoj kev ua no, tshwj xeeb tshaj yog hais tias tom qab ob lub lim piam ntawm lub cev xeeb tub tseem los yog muaj ib tug tsis tiav rho menyuam (tau kev pheej hmoo ntawm kev txawv txav nyob rau hauv lub fetus).

Nqe thiab analogues nyiaj

Analogs "Gynestril thawj coj" ntawm cov tshuaj yog cov nram qab no cov tshuaj: "Ginepriston", "Penkrofton", "Agesta" "Mifepristone", "Zhenale", "Mifolian", "Mifegin", "Mifepreks", "Miropriston".

Nqe xam tau tias yog tshuaj yog heev thiab muaj nqi 5000-6000 rubles.

Xyuas ntawm medicament

Unambiguous thiab kev zoo los yog tsis zoo cov lus hais txog lub "Gynestril" tsis muaj kev npaj. Txawm li cas los, feem ntau cov neeg mob teb favorably txog qhov cuab tam. Lawv cam tias nws yog heev zoo thiab kuj muaj kev nyab xeeb rau lub txais tos.

Nws yuav tsum tau muab sau tseg tias ib txhia neeg, on qhov tsis tooj, feem ntau cai nyob rau hauv lub loj hlob ntawm sab los.

Tag nrho cov kev xyuas hais tias qhov tsawg ntawm cov tshuaj no yuav tsum tau ua tsuas yog tom qab kev sib tham nrog tus kws kho mob.