Analogs of "Koraksan": kev piav qhia thiab kev qhia rau kev siv

Dab tsi yog qhov analogues ntawm Koraksan? Lo lus teb rau lo lus nug no koj yuav pom nyob rau hauv cov ntaub ntawv ntawm qhov tsab xov xwm no. Ntxiv mus, peb yuav muab cov lus qhia rau koj txog kev tsim nyog rau kev siv yeeb tshuaj, yuav ua li cas nws yuav tsum tau noj, thiab lwm yam.

Cov ntaub ntawv hais txog cov khoom muag lam

Koraxan ntsiav tshuaj yog ib qho kev npaj uas txo qis ntawm lub plawv dhia. Cov tshuaj no muaj nyob rau hauv nws qhov kev rho tawm ib yam khoom ua ke xws li ivabradine hydrochloride, thiab lwm yam khoom siv nyob hauv daim lactose monohydrate, magnesium stearate, hmoov txhuv nplej siab, maltodextrin thiab colloidal silicon dioxide.

Pharmacological ua

Coracsan analogs, as Well as npaj rau nws tus kheej, tswj lub plawv dhia los ntawm kev xaiv thiab tshwj xeeb inhibition ntawm cov IF raws ntawm lub sinus ntawm, uas kuj tswj tau qhov ceev diastolic depolarization. Tus cwj pwm nquag ua haujlwm ntawm tus neeg saib xyuas no ua rau txoj kev siv txoj hauv kev kho atrioventricular thiab intraventricular, nrog rau cov kev kho qeeb thiab cov hlab ntaws quav.

Ntawm lwm yam, ivabradine hydrochloride yuav cuam tshuam nrog cov retinal IF-channels, zoo xws li mob plawv YOG, uas koom rau hauv qhov pib ntawm ib ntus kev hloov hauv kev xaav kev pom. Txawm li cas los xij, lub ntsiab ntawm cov tshuaj yeeb dej caw ntawm qhov yeeb tshuaj no yog qhov peev xwm los txo qis tus nqi.

Cov kev qhia rau kev siv lub tsev muag tshuaj

Dab tsi yog cov analogues ntawm \ "Koraksan \" siv, thiab kuj cuab tam nws tus kheej? Cov tshuaj no tau sau rau hauv cov nram qab no:

• Stable angina. Txoj kev kho ntawm tus kab mob no nrog kev pab los ntawm cov kev kho mob no tau ua rau cov neeg mob uas muaj qee qhov kev mob plab zuj zus thaum muaj kev sib cav sib ceg thiab kev tsis pom zoo rau beta-blockers, zoo li nrog lawv.
• Lub plawv tsis ua hauj lwm (mob ntev). Nrog rau kev sib txawv, kev npaj thiab cov analogues ntawm Coraxan yog siv los txo cov xwm txheej ntawm cov hlab plawv. Tom qab tag nrho, qhov loj thev ntawm cov neeg mob yog txuam nrog precisely cov kab mob no.

Contraindications rau kev siv tshuaj "Koraksan"

Analogs ntawm lub npaj "Koraksan" thiab cov tshuaj nws tus kheej tsis raug nquahu kom siv rau hauv cov nram qab no:

• Hypersensitivity rau ivabradine hydrochloride los yog ib lub koom haum pab pawg ntawm tus neeg sawv cev;
• tsis ruaj tsis khov angina ;
• Cardiogenic poob siab;
• Bradycardia (uas yog, nrog lub plawv dhia ntawm yam tsawg kawg yog 60 leej tibsi ib feeb ntawm so);
• Myocardial infarction (mob);
• Hepatic insufficiency (hnyav);
• Mob ntshav siab heev (nyob rau ntawm lub siab kom tsis pub tshaj 90 mm Hg thiab diastolic - tsawg dua 50 hli Hg);
• Tsis muaj zog ntawm qhov ntswg;
• Muaj ntawm tus kab mob electrocardiostimulator;
• Sinoatrial thaiv;
• Lactation thiab cev xeeb tub;
• Atrioventricular blockade ntawm qib 3;
• Simultaneous siv cytochrome system isozymes (xws li, cov tshuaj "Ketoconazole", "Erythromycin", "Itraconazole", "Josamycin", "Clarithromycin", "Ritonavir", "Telithromycin", "Nefazodone" thiab "Nelfinavir");
• Minority (kev ruaj ntseg thiab ua tau zoo ntawm kev siv cuab yeej no rau 18 xyoo tsis tau kawm);
• Lactose intolerance.

Nqa nrog ceev faj!

Cov tshuaj "Koraksan" (nqe, cov qauv ntawm cov kev kho no yuav raug muab tso rau hauv qab no) tsuas yog siv rau tus kws kho mob cov ntawv sau xwb. Nrog ceev faj, cov ntsiav tshuaj no yuav tsum tau ntsuas nrog:

• Hepatic insufficiency (moderately pronounced);
• Lengthing ntawm QT Intervalital (congenital);
• Kev kho mob tsis muaj mob (loj heev);
• Simultaneous thawj coj ntawm cov yeeb tshuaj uas ntev QT;
• Siv cov kua txiv hmab txiv ntoo kua txiv hmab txiv ntoo thiab cov tshuaj tua kab mob ntawm cytochrome isoenzymes;
• Asymptomatic disruption ntawm cov hlwv ntawm sab laug;
• Atrioventrricular blockade ntawm qib 2;
• Stroke (nyuam qhuav kis);
• Retinal pigmentation (nws qhov degeneration);
• Kev poob siab;
• Simultaneous kev tswj cov calcium channel blockers (piv txwv li, Diltiazem lossis Verapamil).

Qhov kev npaj "Koraksan": cov lus qhia rau kev siv

Analogs ntawm qhov kev kho no qhia ua suab tib yam li daim ntawv thov thiab cov tshuaj raws li cov tshuaj hu ua. Tab sis ua ntej siv lawv, koj yuav tsum tau nyeem cov lus qhia txuas nrog thiab nrog koj tus kws kho mob tham.

• Nrog muaj tus mob angina, cov tshuaj no nyob hauv thawj koob tshuaj yog sau rau hauv tus nqi ntawm 10 mg ib hnub twg. Yog tias tom qab 3-4 vas thiv tsis kho, qhov tshuaj txhua hnub yuav tsum tau nce mus txog 15 mg rau ib hnub.
• Nyob rau hauv ntev lub plawv tsis ua hauj lwm xws neeg sawv cev nyob rau hauv thawj zaug koob tshuaj yog muab nyob rau hauv ib tug npaum li ntawm 10 mg ib hnub twg. Yog tias tom qab 2 lub lis piam kho cov nyhuv kho tsis tau, cov tshuaj noj txhua hnub yuav tsum tau nce mus txog 15 mg rau ib hnub.
• Rau cov neeg mob uas muaj hnub nyoog 75 xyoo, qhov kev pom zoo thawj zaug yog 2.5 mg ob zaug ib hnub. Nyob rau hauv lub neej yav tom ntej, koj muaj peev xwm nce lub koob tshuaj ntawm cov tshuaj.
• Rau kev ua txhaum ntawm kev ua rau lub raum, cov neeg mob tau sau ib qho tshuaj "Koraksan" rau ntawm 10 mg rau ib hnub twg. Yog tias tom qab 3-4 vas thiv tsis kho, qhov tshuaj txhua hnub yuav tsum tau nce mus txog 15 mg rau ib hnub.
• Thaum twg kev ua txhaum ntawm daim siab, cov neeg mob tau sau ib qho tshuaj "Koraksan" rau ntawm 10 mg rau ib hnub twg. Yog tias tom qab 3-4 vas thiv tsis kho, qhov tshuaj txhua hnub yuav tsum tau nce mus txog 15 mg rau ib hnub.

Cov kev mob tshwm sim tom qab siv tshuaj

Dua li ntawm qhov ua tau zoo, tsis yog txhua tus neeg uas muaj teebmeem ntawm lub plawv ua rau noj tshuaj no. Ua ntej tshaj, qhov no yog vim muaj qhov tseeb tias nws muaj ntau cov kev mob tshwm sim:

• Qhov muag plooj tsis pom kev thiab nquag hloov hauv qhov kev pom teeb pom kev zoo (los yog hu ua photopsy).
• Bradycardia, qhov ntswg arrhythmia, ventricular arrythmia, angina (tsis ruaj tsis khov), palpitations, heart attack myocardial infarction, hypotension, supraventricular extrasystoles, atrial fibrillation, ventricular tachycardia, thiab myocardial ischemia.
• Zawv plab, xeev siab thiab cem quav.
• Mob taub hau (tshwj xeeb tshaj yog nyob rau lub hli 1 ntawm kev kho mob), kiv taub hau, ua tsis taus pa, nqaij ntshiv, vertigo thiab tsaus muag.
• Hyperuricemia thiab eosinophilia.
• Cov nqaij pob liab liab, angioedema, khaus khaus, urticaria thiab erythema.
• Asthenia, mob siab thiab qaug zog.

Cov tshuaj "Koraksan": xyuas, analogues ntawm yeeb tshuaj

Cov neeg uas pheej siv qhov cuab yeej no, hais txog nws tsuas zoo. Txawm li cas los, xws li ib tug yeeb tshuaj yog kim heev. Yog li, rau 56 ntsiav tshuaj ntawm cov tshuaj "Coraxan" koj yuav tsum tau them txog 1200 Lavxias rub. Hauv no regard, feem ntau cov neeg mob uas muaj kab mob plawv feem ntau pib yuav pheej yig dua analogs ntawm cov tshuaj.

Cov tshuaj hauv qab no tuaj yeem raug cais raws li cov qauv sib xws ntawm tus neeg sawv cev rau lub cev:

• Ivabradine hydrochloride;
• Iwabradine.

Raws li cov curative siv (kev npaj npaj rau kev kho ntawm angina pectoris):

• Amlodipine;
• Asparks;
• Atenolol;
• "Aspirin Cardio";
• Betalok;
• "Validol";
• Hypoxen;
• "Isoket";
• Diltiazem;
• "Isolong";
• Carvedilol;
• Concor;
• "Corvitol";
• Lokren;
• "Cordipin";
• Corinthard retard;
• Metoprolol;
• Mildronate;
• "Monosan";
• "Nitroglycerin";
• "Papaverin";
• "Nitrogen";
• "Nifedipine";
• "Normodipin";
• "Plavix";
• "Prestans";
• Stamlo;
• "Sustonite";
• "Trimetazidine";
• "Tenox";
• "Egilok";
• "Efoks Ntev" thiab lwm tus.