'Dexamethasone' - qhov muag dauv

"Dexamethasone" (poob ophthalmic) muaj ib tug qhia tau antiallergic, antiinflammatory thiab antiexudative kev txiav txim.

Cov tshuaj ua num ua ke nrog kev protein receptors phiaj ntaub so ntswg thiab regulates kev qhia ntawm noob nyob rau hauv kortikoidzavisimyh. Yog li, cov tshuaj ntxim rau cov protein synthesis. "Dexamethasone" (qhov muag dauv) txo qhov tsim kom muaj, tso tawm thiab kev ua si ntawm inflammatory kev sib kho (xws li, kinin, ib tug histamine, lysosomal enzymes, prostaglandins).

Lub medicament txhawb tsuj ntawm cell tsiv teb tsaws rau inflammatory foci, nce vascular permeability txo nws, thiab vasodilation. "Dexamethasone" (qhov muag dauv) muaj ib tug stabilizing ntxim rau lysosomal enzymes nyob rau hauv lub week ntawm leukocytes suppressive ntxim rau antibody synthesis. Lub medicament muab antigenic paub, induces lub tsim ntawm lipocortin, muaj ib tug inhibitory ntxim rau qhov kev tso tawm ntawm inflammatory kev sib kho los ntawm eosinophils. Thaum zoo li no yog ua li cas mus rau stabilize mast cell week. Cov los ua rau kom cov hluav ntawm lub inflammatory teb nyob rau hauv cov nqaij nyob rau hauv cov lus teb rau tiv thaiv kab mob, tshuaj los yog cov neeg kho tshuab kev puas tsuaj.

Lub duration ntawm lub anti-inflammatory nyhuv ntawm medicament "Dexamethasone" (qhov muag dauv) tom qab thawj coj ntawm ib tug nco ntawm cov tshuaj yog los ntawm plaub mus rau yim lub sij hawm.

Cov tshuaj penetrates zoo rau hauv lub conjunctiva thiab corneal epithelium. Tom qab cov kev taw qhia ntawm dej nyob rau hauv lub aqueous ophthalmic kho concentration yog mus txog. Nyob rau hauv tus neeg mob ntawm kev raug mob los yog o ntawm txheej cim nce nyob rau hauv tus nqi ntawm allergic (allergic).

Cov tshuaj no yog absorbed rau hauv lub system yog ib tug tsawg kawg nkaus. Hais txog 60-70% ntawm medicament nkag mus rau lub kev system, khi rau ntshav proteins.

Drug metabolism nyob rau hauv lub siab nyob rau hauv tus tsitohromsoderzhaschih enzymes. Xaus metabolites ua nyob rau hauv cov quav.

"Dexamethasone" ncos yog qhia rau purulent thiab tsis haum conjunctivitis, keratitis, keratoconjunctivitis, yog tsis nrog epithelial txhab, blepharitis, scleritis, episcleritis, uveitis, chorioretinitis, blefakonyunktivite. Lub medicament yog tseem muab nrog optic neuritis, sympathetic ophthalmia, raws li zoo raws li kev kho mob thiab kev tiv thaiv ntawm o nyob rau hauv lub postoperative lub sij hawm, thiab tom qab qhov kev raug mob.

Rau cov neeg laus mob mob dosing lub sij hawm yog 1-2 dauv los ntawm plaub mus rau tsib lub sij hawm ib hnub twg rau ob hnub, ua raws li los ntawm cov tshuaj siv 1-2 dauv mus rau plaub zaug ib hnub twg rau plaub mus rau rau hnub.

Qhov siab tshaj plaws ntev ntawm kev siv ntawm cov tshuaj - rau lub lim tiam.

Nyob rau hauv kev tsis haum cov kab mob ntawm lub qhov muag tshuaj ua 1-2 ncos txog li tsib lub sij hawm nyob rau hauv ob hnub. Tom ntej no, tsim lub tsheb txhob sibtsoo abolition ntawm cov tshuaj rau ib tug los yog ob lub lis piam.

Rau kev tiv thaiv thiab kev kho mob ntawm kev raug mob ntawm lub ceev ceev tom qab phais (filtering antiglaucoma phais) los yog kev poob plig lub qhov muag dauv "Dexamethasone" yog siv nyob rau hauv hnub ntawm kev phais los yog nyob rau tom qab hnub phais.

Tom qab lub cataract phais, kev pab rau retinal detachment thiab tom qab cov tshuaj raug mob yog thaum pib los mus siv rau hauv lub yim hnub.

Nyob rau hauv cov me nyuam (los ntawm rau mus rau kaum ob xyoos) nyob rau hauv cov kev kho mob ntawm inflammatory thiab tsis haum tej yam kev mob lub tshuaj no yog txhaj los nco txog peb lub sij hawm ib hnub twg. Duration ntawm lub chav kawm - los ntawm xya mus rau kaum hnub. Yog hais tias tsim nyog, kev siv ntawm cov medicament yuav tau mus ntxiv tom qab lub fluorescein sojntsuam rau lub thib kaum hnub.

Raws li kev xyaum qhia tau hais tias, cov tshuaj yog zam lub txim rau, nyob rau hauv Feem ntau, zoo. Txawm li cas los, nyob rau hauv tej rooj plaub, tej zaum yuav tshwm sim sab los. Yog li ntawd, cov tshuaj, tshwj xeeb tshaj yog rau cataract yuav tsum tau siv nyob rau hauv kev kho mob saib xyuas thiab nruj me ntsis nram qab no rau cov lus qhia.