"Chloramphenicol" - qhov muag dauv. Cov lus qhia rau kev siv

Nrog lub qhov muag cov kab mob ntau zaus siv cov tshuaj "chloramphenicol". Rau lub ob lub qhov muag yog ib tug ntawm qhov zoo tshaj ntawm txoj kev pab los mus kov yeej qhov kev txiav txim ntawm cov teeb meem microorganisms. Ncos muaj 0.25% cov kua ntawm chloramphenicol, uas yog lub ntsiab active khoom sib ua zaub mov ntawm cov tshuaj. Chloramphenicol yog feem ntau ua los ntawm manufacturers nyob rau hauv vials muaj 5 ml ntawm lub active tshuaj nyob rau hauv ib pawg pob yog tseem dropper hau.

Tshuaj "chloramphenicol" (qhov muag dauv) qhia piav raws li ib tug tshuaj tua kab mob uas yuav siv tau nyob rau hauv kev kho ntau yam ntawm cov kab mob. Nws muaj antimicrobial kev ua si.

Chloramphenicol muaj zog uas muab ib tug bacteriostatic nyhuv thiab siab kev ua ntawm cov tshuaj tiv thaiv ib tug xov tooj ntawm Gram-zoo thiab Gram-tsis zoo kab mob: Staphylococcus spp, Neisseria gonorrhoeae, Shigella spp .. thiab lwm tus neeg. Cov tshuaj yeeb dej caw muaj kev ua si tiv thaiv kab mob los thiab hais tias feeb yog resistant rau penicillins. Nyob rau lwm cov tes, cov kuj ntawm cov teeb meem kab mob rau chloramphenicol yog tsim heev maj mam.

Lub pharmacokinetic thaj chaw ntawm cov tshuaj "chloramphenicol" (qhov muag dauv) qhia characterizes raws li nram no. Thaum tau txais nws cov tshuaj Cheebtsam sai thiab yuav luag tag absorbed los ntawm cov hnyuv ib ntsuj av. Ntxiv mus, nws bioavailability yog 80%. Cov tshuaj muaj peev xwm mus sai heev faib nyob rau hauv lub cev. Cov theem ntawm chloramphenicol ruaj rau ntshav cov nqaijrog yog 50-60% thiab nws cov metabolization nyob rau hauv lub siab. ib nrab-lub neej ntawm lub ntsiab active tshuaj tshuaj yog hais txog 1.5-3.5 teev, thiab dua li nqa feem nyob rau hauv cov zis.

Cov tshuaj "chloramphenicol" (qhov muag dauv) daim ntawv xav tias nyob rau hauv cov kev tshwm sim ntawm kis thiab inflammatory kab mob tshwm sim los ntawm kab mob rhiab rau chloramphenicol. Qhov no, saum toj no tag nrho, typhoid kub taub hau, dysentery, hnoos, trachoma. Pib tshuaj nyob rau hauv cov kev kho mob ntawm mob ntsws, meningitis thiab lwm yam kab mob txhab.

Nyob rau hauv cov kev kho mob ntawm daim tawv nqaij suppurative txhab, boils, trophic ulcers thiab kub nyhiab, raws li ib tug txoj cai, cov tshuaj no yog siv raws li ib tug sab nraud tus neeg saib xyuas. Rau cov tshuaj pleev tshuaj qhia rau cov kev kho mob ntawm ocular inflammatory kab mob.

Nyob rau hauv appointing lub tshuaj no yog pom zoo kom hais tias ib tug neeg ntau npaum regimen. Rau cov neeg laus, ib koob tshuaj tshuaj ntawm 500 mg rau peb-plaub lub sij hawm lub txais tos rau ib hnub. Rau cov me nyuam nws yog pom zoo kom siv ib tug txawv, nyob ntawm seb tus me nyuam hnyav thiab muaj hnub nyoog.

Rau cov me nyuam mus txog rau 3 xyoo, pom zoo koob tshuaj yog 15 mg rau ib 1 kg ntawm lub cev hnyav, rau cov me nyuam hnub nyoog peb mus rau yim lub xyoo - 150-200 mg, thiab rau cov laus dua cov me nyuam, cov tshuaj yog 200-400 mg. Nyob rau hauv txhua tus neeg mob, cov tshuaj yuav tsum tau coj peb los yog plaub lub sij hawm tsis pub dhau 7-10 hnub.

Thaum ua ntawv thov topically thov tshuaj rau gauze los los yog ncaj qha rau ntawm cov cheeb tsam. Nyuam nyob rau hauv cov ntaub ntawv no yog ua los ntawm cov Team sib ntawm 1-3 hnub.

Chloramphenicol (qhov muag dauv) daim ntawv qhia kom siv nyob rau hauv cov kev kho mob ntawm cov kab mob ophthalmic nyob rau hauv ib tug complex kho regimen.

Qhov no tshuaj tej zaum yuav ua rau kev phiv. Coj cov ntsiab lus mus rau lub tseem tshwm sim ntawm aplastic anemia, xeev siab, ntuav, feem ntau yuav tsau mob taub hau. Nyob rau hauv tsawg zaus, muaj tsis meej pem, fem, hallucinations sib txawv, uas tshwm sim los qhov muag dauv "chloramphenicol". Xyuas ntawm cov neeg mob uas coj cov tshuaj, hais tias thaum lub sij hawm txais tos tej zaum yuav tshwm sim hauv daim tawv nqaij ua pob ua xyua thiab lwm yam sab nraud stimuli.

Tsis txhob noj cov tshuaj rau cov neeg uas tau raug tshuaj lawm cov kab mob ntawm cov ntshav thiab daim tawv nqaij, cev xeeb tub cov poj niam thiab cov me nyuam mus txog peb lub xyoos.

Tshwj xeeb mention yuav tsum ceev faj nyob rau hauv qhov kev siv ntawm cov tshuaj nyob rau hauv cov neeg mob uas tau muaj ua ntej kev kho mob zaug cytotoxic tshuaj thiab radiotherapy zaug.

Nrog rau cov simultaneous siv penicillin chloramphenicol tes nrog lawv bactericidal kev txiav txim.